Registro completo |
Provedor de dados: |
BJMBR
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País: |
Brazil
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Título: |
Prognostic effect of high-flux hemodialysis in patients with chronic kidney disease
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Autores: |
Li,X.
Xu,H.
Xiao,X.C.
Deng,S.L.
Wang,W.
Tang,R.
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Data: |
2016-01-01
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Ano: |
2016
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Palavras-chave: |
High-flux hemodialysis
Low-flux hemodialysis
Chronic kidney disease
Chronic renal failure
All-cause death rate
Cardiovascular death rate
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Resumo: |
We investigated the prognostic effects of high-flux hemodialysis (HFHD) and low-flux hemodialysis (LFHD) in patients with chronic kidney disease (CKD). Both an electronic and a manual search were performed based on our rigorous inclusion and exclusion criteria to retrieve high-quality, relevant clinical studies from various scientific literature databases. Comprehensive meta-analysis 2.0 (CMA 2.0) was used for the quantitative analysis. We initially retrieved 227 studies from the database search. Following a multi-step screening process, eight high-quality studies were selected for our meta-analysis. These eight studies included 4967 patients with CKD (2416 patients in the HFHD group, 2551 patients in the LFHD group). The results of our meta-analysis showed that the all-cause death rate in the HFHD group was significantly lower than that in the LFHD group (OR=0.704, 95%CI=0.533-0.929, P=0.013). Additionally, the cardiovascular death rate in the HFHD group was significantly lower than that in the LFHD group (OR=0.731, 95%CI=0.616-0.866, P<0.001). The results of this meta-analysis clearly showed that HFHD decreases all-cause death and cardiovascular death rates in patients with CKD and that HFHD can therefore be implemented as one of the first therapy choices for CKD.
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Tipo: |
Info:eu-repo/semantics/article
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Idioma: |
Inglês
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Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000100706
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Editor: |
Associação Brasileira de Divulgação Científica
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Relação: |
10.1590/1414-431x20154708
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Formato: |
text/html
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Fonte: |
Brazilian Journal of Medical and Biological Research v.49 n.1 2016
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Direitos: |
info:eu-repo/semantics/openAccess
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