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Provedor de dados:  BJMBR
País:  Brazil
Título:  Comorbidity of psychiatric disorders and symmetric distal polyneuropathy among type II diabetic outpatients
Autores:  Moreira,R.O.
Papelbaum,M.
Fontenelle,L.F.
Appolinario,J.C.
Ellinger,V.C.M.
Coutinho,W.F.
Zagury,L.
Data:  2007-02-01
Ano:  2007
Palavras-chave:  Anxiety
Depressive symptoms
Diabetic neuropathy
Symmetric distal polyneuropathy
Psychiatric interview
Psychometric scales
Resumo:  The objective of the present study was to establish the frequency of psychiatric comorbidity in a sample of diabetic patients with symmetric distal polyneuropathy (SDPN). Sixty-five patients with type 2 diabetes mellitus were selected consecutively to participate in the study at Instituto Estadual de Diabetes e Endocrinologia. All patients were submitted to a complete clinical and psychiatric evaluation, including the Portuguese version of the structured clinical interview for DSM-IV, the Beck Depression Inventory, the Neuropathy Symptom Score, and Neuropathy Disability Score. SDPN was identified in 22 subjects (33.8%). Patients with and without SDPN did not differ significantly regarding sociodemographic characteristics. However, a trend toward a worse glycemic control was found in patients with SDPN in comparison to patients without SDPN (HbA1c = 8.43 ± 1.97 vs 7.48 ± 1.95; P = 0.08). Patients with SDPN exhibited axis I psychiatric disorders significantly more often than those without SDPN (especially anxiety disorders, in general (81.8 vs 60.0%; P = 0.01), and major depression - current episode, in particular (18.2 vs 7.7%; P = 0.04)). The severity of the depressive symptoms correlated positively with the severity of SDPN symptoms (r = 0.38; P = 0.006), but not with the severity of SDPN signs (r = 0.07; P = 0.56). In conclusion, the presence of SDPN seems to be associated with a trend toward glycemic control. The diagnosis of SDPN in diabetic subjects seems also to be associated with relevant psychiatric comorbidity, including anxiety and current mood disorders.
Tipo:  Info:eu-repo/semantics/other
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000200015
Editor:  Associação Brasileira de Divulgação Científica
Relação:  10.1590/S0100-879X2006005000051
Formato:  text/html
Fonte:  Brazilian Journal of Medical and Biological Research v.40 n.2 2007
Direitos:  info:eu-repo/semantics/openAccess
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