| Registro completo |
| Provedor de dados: |
BJM
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| País: |
Brazil
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| Título: |
Anti dermatophytic therapy: prospects for the discovery of new drugs from natural products
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| Autores: |
Soares,Luciana Arantes
Sardi,Janaína de Cássia Orlandi
Gullo,Fernanda Patrícia
Pitangui,Nayla de Souza
Scorzoni,Liliana
Leite,Fernanda Sangalli
Giannini,Maria José Soares Mendes
Almeida,Ana Marisa Fusco
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| Data: |
2013-12-01
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| Ano: |
2013
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| Palavras-chave: |
Dermatophytes
Filamentous fungi
Natural products
Synthetic product
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| Resumo: |
Millions of people and animals suffer from superficial infections caused by a group of highly specialized filamentous fungi, the dermatophytes, which only infect keratinized structures. With the appearance of AIDS, the incidence of dermatophytosis has increased. Current drug therapy used for these infections is often toxic, long-term, and expensive and has limited effectiveness; therefore, the discovery of new anti dermatophytic compounds is a necessity. Natural products have been the most productive source for new drug development. This paper provides a brief review of the current literature regarding the presence of dermatophytes in immunocompromised patients, drug resistance to conventional treatments and new anti dermatophytic treatments.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000400003
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| Editor: |
Sociedade Brasileira de Microbiologia
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| Relação: |
10.1590/S1517-83822014005000011
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| Formato: |
text/html
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| Fonte: |
Brazilian Journal of Microbiology v.44 n.4 2013
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| Direitos: |
info:eu-repo/semantics/openAccess
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