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Provedor de dados:  BJM
País:  Brazil
Título:  The function of lexical motifs in the organization of the Actinomycetes 5S rRNAs
Autores:  Rodrigues-Subacius,Sandra M
Padilla,Gabriel
Data:  2007-09-01
Ano:  2007
Palavras-chave:  Actinomycetes
5S rRNA
GC pressure
Linguistic analysis
Lexical motifs
Resumo:  This work shows results obtained by employing the linguistic method to identify biologically meaningful sites in Actinomycetes 5S rRNAs. The approach adopted identifies triplet-words, along the base sequence of 5S rRNA, located mainly at the alpha and beta domains of the 5S secondary structure. There are triplet-words representing universal protein binding sites that include important prokaryote signatures, and sites strategically located in critical regions related to the formation of the 5S ribonucleoproteins (RNP) complex. In those sites, where the GC pressure promoted substitutions, the analysis demonstrates that alterations did not affect their biological significance. Sites formed by GGY (or more rarely GGR), continued to play an important role as ribosomal proteins rpL18 and rpL5 protein receptors. The data suggest that instead of increasing the molecular variability, expected for the diversity in species and habitats occupied for the group, GC pressure functioned as a reducer mechanism for the inter-specific diversity.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822007000300036
Editor:  Sociedade Brasileira de Microbiologia
Relação:  10.1590/S1517-83822007000300036
Formato:  text/html
Fonte:  Brazilian Journal of Microbiology v.38 n.3 2007
Direitos:  info:eu-repo/semantics/openAccess
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