| Registro completo |
| Provedor de dados: |
BJM
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| País: |
Brazil
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| Título: |
Antimicrobial resistance in Enterobacteriaceae in Brazil: focus on β-lactams and polymyxins
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| Autores: |
Sampaio,Jorge Luiz Mello
Gales,Ana Cristina
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| Data: |
2016-12-01
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| Ano: |
2016
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| Palavras-chave: |
ESBL
KPC
NDM
Extended spectrum β-lactamases
New Delhi metallo-β-lactamase
Klebsiella pneumoniae carbapenemase
Polymyxin B
Colistin
Antimicrobial resistance
Carbapenemases
Brazil
Enterobacteriaceae
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| Resumo: |
ABSTRACT During the last 30 years there has been a dissemination of plasmid-mediated β-lactamases in Enterobacteriaceae in Brazil. Extended spectrum β-lactamases (ESBL) are widely disseminated in the hospital setting and are detected in a lower frequency in the community setting. Cefotaximases are the most frequently detected ESBL type and Klebsiella pneumoniae is the predominant species among ESBL producers. Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae became widely disseminated in Brazil during the last decade and KPC production is currently the most frequent resistance mechanism (96.2%) in carbapenem resistant K. pneumoniae. To date KPC-2 is the only variant reported in Brazil. Polymyxin B resistance in KPC-2-producing K. pneumoniae has come to an alarming rate of 27.1% in 2015 in São Paulo, the largest city in Brazil. New Delhi metallo-β-lactamase was detected in Brazil in 2013, has been reported in different Brazilian states but are not widely disseminated. Antimicrobial resistance in Enterobacteriaceae in Brazil is a very serious problem that needs urgent actions which includes both more strict adherence to infection control measures and more judicious use of antimicrobials.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822016000500031
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| Editor: |
Sociedade Brasileira de Microbiologia
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| Relação: |
10.1016/j.bjm.2016.10.002
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| Formato: |
text/html
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| Fonte: |
Brazilian Journal of Microbiology v.47 suppl.1 2016
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| Direitos: |
info:eu-repo/semantics/openAccess
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