| Registro completo |
| Provedor de dados: |
BJM
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| País: |
Brazil
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| Título: |
Nosocomial candidiasis in Rio de Janeiro State: Distribution and fluconazole susceptibility profile
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| Autores: |
Neufeld,Paulo Murillo
Melhem,Marcia de Souza Carvalho
Szeszs,Maria Walderez
Ribeiro,Marcos Dornelas
Amorim,Efigênia de Lourdes Teixeira
Silva,Manuela da
Lazéra,Marcia dos Santos
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| Data: |
2015-06-01
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| Ano: |
2015
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| Palavras-chave: |
Candida
Fluconazole
Antifungal susceptibility
Disk diffusion method
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| Resumo: |
One hundred and forty-one Candida species isolated from clinical specimens of hospitalized patients in Rio de Janeiro, Brazil, during 2002 to 2007, were analized in order to evaluate the distribution and susceptibility of these species to fluconazole. Candida albicans was the most frequent species (45.4%), followed by C. parapsilosis sensu lato (28.4%), C. tropicalis (14.2%), C. guilliermondii (6.4%), C. famata (2.8%), C. glabrata (1.4%), C. krusei (0.7%) and C. lambica (0.7%). The sources of fungal isolates were blood (47.5%), respiratory tract (17.7%), urinary tract (16.3%), skin and mucous membrane (7.1%), catheter (5.6%), feces (2.1%) and mitral valve tissue (0.7%). The susceptibility test was performed using the methodology of disk-diffusion in agar as recommended in the M44-A2 Document of the Clinical and Laboratory Standards Institute (CLSI). The majority of the clinical isolates (97.2%) was susceptible (S) to fluconazole, although three isolates (2.1%) were susceptible-dose dependent (S-DD) and one of them (0.7%) was resistant (R). The S-DD isolates were C. albicans, C. parapsilosis sensu lato and C. tropicalis. One isolate of C. krusei was resistant to fluconazole. This work documents the high susceptibility to fluconazole by Candida species isolated in Rio de Janeiro, Brazil.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000200477
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| Editor: |
Sociedade Brasileira de Microbiologia
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| Relação: |
10.1590/S1517-838246220120023
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| Formato: |
text/html
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| Fonte: |
Brazilian Journal of Microbiology v.46 n.2 2015
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| Direitos: |
info:eu-repo/semantics/openAccess
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