| Registro completo |
| Provedor de dados: |
BJM
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| País: |
Brazil
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| Título: |
Antibacterial activity of orsellinates
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| Autores: |
Gomes,Alcir Teixeira
Smania Júnior,Artur
Seidel,Cintia
Smania,Elza de Fátima Albino
Honda,Neli Kika
Roese,Fernanda Mesquita
Muzzi,Rozanna Marques
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| Data: |
2003-07-01
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| Ano: |
2003
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| Palavras-chave: |
Orsellinates
Lecanoric acid
Orsellinic acid
Antibacterial activity
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| Resumo: |
In order to obtain new compounds with antibacterial activity, the derivatives 2,4-dihydroxy-6-methylbenzoic acid (orsellinic acid) and 2,4-dihydroxy-6-methylbenzoates (orsellinates) were obtained through alcoholyses of lecanoric acid. All these substances were tested against Gram-positive and Gram-negative bacteria by a microdilution method. Staphylococcus aureus, Xanthomonas campestris var. vesicatoria and Ralstonia solanacearum were most sensitive to n-propyl 2,4-dihydroxy-6-methylbenzoate, n-pentyl 2,4-dihydroxy-6-methylbenzoate and n-hexyl 2,4-dihydroxy-6-methylbenzoate with MIC (Minimal Inhibitory Concentration) values ranging from 62.5 to 7.8 µg×mL¹. These results showed that homologation in carbon chain may lead to compounds with more pronunced activities.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822003000300002
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| Editor: |
Sociedade Brasileira de Microbiologia
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| Relação: |
10.1590/S1517-83822003000300002
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| Formato: |
text/html
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| Fonte: |
Brazilian Journal of Microbiology v.34 n.3 2003
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| Direitos: |
info:eu-repo/semantics/openAccess
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