| Registro completo |
| Provedor de dados: |
BJM
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| País: |
Brazil
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| Título: |
Collagenolytic enzymes produced by fungi: a systematic review
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| Autores: |
Wanderley,Maria Carolina de Albuquerque
Duarte Neto,José Manoel Wanderley
Lima Filho,José Luiz de
Lima,Carolina de Albuquerque
Teixeira,José António Couto
Porto,Ana Lúcia Figueiredo
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| Data: |
2017-03-01
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| Ano: |
2017
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| Palavras-chave: |
Collagenase
Fungus
Characterization
Purification
Production
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| Resumo: |
Abstract Specific proteases capable of degrading native triple helical or denatured collagen have been required for many years and have a large spectrum of applications. There are few complete reports that fully uncover production, characterization and purification of fungi collagenases. In this review, authors searched through four scientific on line data bases using the following keywords (collagenolytic OR collagenase) AND (fungi OR fungus OR fungal) AND (production OR synthesis OR synthesize) AND (characterization). Scientific criteria were adopted in this review to classify found articles by score (from 0 to 10). After exclusion criteria, 21 articles were selected. None obtained the maximum of 10 points defined by the methodology, which indicates a deficiency in studies dealing simultaneously with production, characterization and purification of collagenase by fungi. Among microorganisms studied the non-pathogenic fungi Penicillium aurantiogriseum and Rhizoctonia solani stood out in volumetric and specific collagenase activity. The only article found that made sequencing of a true collagenase showed 100% homology with several metalloproteinases fungi. A clear gap in literature about collagenase production by fungi was verified, which prevents further development in the area and increases the need for further studies, particularly full characterization of fungal collagenases with high specificity to collagen.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822017000100013
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| Editor: |
Sociedade Brasileira de Microbiologia
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| Relação: |
10.1016/j.bjm.2016.08.001
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| Formato: |
text/html
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| Fonte: |
Brazilian Journal of Microbiology v.48 n.1 2017
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| Direitos: |
info:eu-repo/semantics/openAccess
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