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Provedor de dados:  BJPS
País:  Brazil
Título:  Development and evaluation of an emulsion containing lycopene for combating acceleration of skin aging
Autores:  Cefali,Letícia Caramori
Souza-Moreira,Tatiana Maria
Corrêa,Marcos Antônio
Salgado,Hérida Regina Nunes
Isaac,Vera Lucia Borges
Data:  2015-09-01
Ano:  2015
Palavras-chave:  Carotenoid/antioxidant activity
Lycopene/emulsion form/cytotoxicity
Lycopene/emulsion form/permeation
Lycopene/emulsion form/rheology
Lycopene/emulsion form/thermal analyses
Phytocosmetics
Skin aging/treatment
Resumo:  Lycopene, a carotenoid and potent antioxidant is found in large quantities in tomatoes. Lycopene combats diseases, such as cardiovascular disease and different types of cancer, including prostate cancer. However, its topical use in emulsion form for the combat of skin aging is under-explored. The aim of the present study was to develop an emulsion containing lycopene extracted from salad tomatoes and evaluate its cytotoxicity, stability, rheological behavior, antioxidant activity and phytocosmetic permeation. The developed cosmetic comprised an oil phase made up of shea derivatives and was evaluated in terms of its physiochemical stability, spreadability, thermal analysis, rheological behavior, microbiological quality, cytotoxicity, antioxidant activity, cutaneous permeation and retention. The results demonstrate that this phytocosmetic is stable, exhibits satisfactory rheological behavior for a topical formula and is a promising product for combating skin aging.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000300579
Editor:  Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
Relação:  10.1590/S1984-82502015000300010
Formato:  text/html
Fonte:  Brazilian Journal of Pharmaceutical Sciences v.51 n.3 2015
Direitos:  info:eu-repo/semantics/openAccess
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