| Registro completo |
| Provedor de dados: |
60
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| País: |
Brazil
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| Título: |
Stability study of azithromycin in ophthalmic preparations
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| Autores: |
Moreno,Andréia de Haro
Silva,Maria Fernanda Conz da
Salgado,Hérida Regina Nunes
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| Data: |
2009-06-01
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| Ano: |
2009
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| Palavras-chave: |
Azithromycin/stability study
Bioassay
Photodegradation
Ophthalmic preparations
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| Resumo: |
A stability study of azithromycin in ophthalmic preparations was developed by submission to different types of light, temperature and pH, using the biodiffusion assay (cylinder 3 x 3) for the quantifications. Bacillus subtilis, ATCC 9372, was used as test organism. The used concentration range was of 50 to 200 µg/mL. The study demonstrated that the drug suffered degradation when submitted to the ultraviolet light, germicide light, solar luminosity, acid solution, basic solution and hydrogen peroxide solution. The results were analyzed by the analysis of variance (ANOVA).
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000200005
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| Editor: |
Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
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| Relação: |
10.1590/S1984-82502009000200005
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| Formato: |
text/html
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| Fonte: |
Brazilian Journal of Pharmaceutical Sciences v.45 n.2 2009
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| Direitos: |
info:eu-repo/semantics/openAccess
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