| Registro completo |
| Provedor de dados: |
BJPS
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| País: |
Brazil
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| Título: |
Production and characterization of alginate-starch-chitosan microparticles containing stigmasterol through the external ionic gelation technique
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| Autores: |
Fujiwara,Gislene Mari
Campos,Ranieri
Costa,Camila Klocker
Dias,Josiane de Fátima Gaspari
Miguel,Obdulio Gomes
Miguel,Marilis Dallarmi
Marques,Francisco de Assis
Zanin,Sandra Maria Warumby
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| Data: |
2013-09-01
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| Ano: |
2013
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| Palavras-chave: |
Stigmasterol/microencapsulation
Microencapsulation
Sodium alginate/drugs coating
Chitosan/drugs coating
Starch/drugs coating
Natural polymers/drugs coating
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| Resumo: |
Stigmasterol - a plant sterol with several pharmacological activities - is susceptible to oxidation when exposed to air, a process enhanced by heat and humidity. In this context, microencapsulation is a way of preventing oxidation, allowing stigmasterol to be incorporated into various pharmaceutical forms while increasing its absorption. Microparticles were obtained using a blend of polymers of sodium alginate, starch and chitosan as the coating material through a one-stage process using the external gelation technique. Resultant microparticles were spherical, averaging 1.4 mm in size. Encapsulation efficiency was 90.42% and method yield 94.87%. The amount of stigmasterol in the oil recovered from microparticles was 9.97 mg/g. This technique proved feasible for the microencapsulation of stigmasterol.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000300015
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| Editor: |
Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
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| Relação: |
10.1590/S1984-82502013000300015
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| Formato: |
text/html
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| Fonte: |
Brazilian Journal of Pharmaceutical Sciences v.49 n.3 2013
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| Direitos: |
info:eu-repo/semantics/openAccess
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