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Provedor de dados:  BJPS
País:  Brazil
Título:  Stability of Tilo® tablets formulation obtained from dry extract of Justice pectoralis Jacq.
Autores:  Rodríguez-Chanfrau,Jorge E.
Núñez-Figueredo,Yanier
Fuste-Moreno,Viviana
Data:  2015-03-01
Ano:  2015
Palavras-chave:  Justicia pectoralis/pharmacognosy
Medicinal plants
Phytomedicines
Coumarins/determination
High Performance Liquid Chromatography/phytomedicines analysis
Phytomedicines/stability studies
Tilo®/tablets/stability studies
Resumo:  Justicia pectoralis Jacq., Acanthaceae, is a herb known popularly in Cuba as Tilo and used traditionally as sedative. The development in a solid pharmaceutical (Tablets 100 mg) using dry extract of Justicia pectolaris aqueous extract is of interest for the development of phytomedicines, which uses this active raw material. The aim of the present study was to carry out chemical and biological stability studies to the formulation. A method of coumarin determination by High Performance Liquid Chromatography (HPLC) was used and validated. The stability studies during different periods of time (24 months) showed a stability of the product stored at 32 ± 2 °C, and protected of the light.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000100193
Editor:  Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
Relação:  10.1590/S1984-82502015000100019
Formato:  text/html
Fonte:  Brazilian Journal of Pharmaceutical Sciences v.51 n.1 2015
Direitos:  info:eu-repo/semantics/openAccess
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