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Provedor de dados:  BJPS
País:  Brazil
Título:  Intralesional corticosteroid injection as an effective treatment method for oral lesions: a meta-analysis
Autores:  Gholizadeh,Narges
Sadrzadeh-Afshar,Maryam-Sadat
Sheykhbahaei,Nafiseh
Data:  2020-01-01
Ano:  2020
Palavras-chave:  Intralesional corticosteroid injection
Triamcinolone
Betamethasone
Oral lesions
Oral disorders
Steroid injection
Resumo:  Intralesional corticosteroid injection (ICSI) is known as one of the main methods used for treating a wide range of lesions. It also results in a high concentration of drugs at lesion sites, with minimal systemic absorption. Thus, this study aimed to provide a review of the intralesional corticosteroid injection (ICSI) indications in the treatment of oral lesions. To this end; relevant key words were searched in the databases of PubMed, Google Scholar, Scopus, ScienceDirect, and UpToDate in the present study. Accordingly, the results of a total number of 62 case reports or case series articles were used in this study and the positive therapeutic effects of intralesional corticosteroid injection (ICSI) in 23 common oral lesions were reported. The most common type of intralesional steroid in the treatment of oral lesions was triamcinolone. No significant difference was also observed in terms of pain in patients following the use of steroid alone or in combination with anesthetic agents; moreover, the reported side effects of this method were exceptionally rare and transient. It was concluded that the intralesional corticosteroid injection (ICSI) could be one of the effective therapeutic methods with no significant problems in many oral lesions such as inflammatory, immunologic, and vascular ones due to its higher therapeutic effects than other topical forms of steroids and fewer side effects than systemic corticosteroid.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100701
Editor:  Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
Relação:  10.1590/s2175-97902019000418077
Formato:  text/html
Fonte:  Brazilian Journal of Pharmaceutical Sciences v.56 2020
Direitos:  info:eu-repo/semantics/openAccess
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