| Registro completo |
| Provedor de dados: |
Braz. J. Vet. Res. Anim. Sci.
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| País: |
Brazil
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| Título: |
Effects of milk from goat fed Crotalaria spectabilis seeds on growing rats
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| Autores: |
MEDEIROS,Rosane Maria Trindade de
GÓRNIAK,Silvana Lima
GUERRA,José Luis
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| Data: |
1999-01-01
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| Ano: |
1999
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| Palavras-chave: |
Milk
Pyrrolizidine alkaloids
Crotalaria spectabilis
Poisoning
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| Resumo: |
Seeds of Crotalaria spectabilis, containing the pyrrolizidine alkaloid (PA) monocrotaline (MCT), were fed to a lactating dairy goat. Milk from this goat was fed to rats for 8 weeks to determine whether MCT or its toxic metabolites are transferred into the goats milk. Rats from the experimental group showed significantly higher (p<0.05) serum levels of ALT, AST, GGT and LDH and less weight gains (p<0.05) than control rats. The most significant lesions in rats consuming the experimental ration were mild to moderate interstitial pneumonia and a vacuolar degeneration and occasionally necrosis of periportal hepatocytes. The results of this study indicate that the PA and/or its metabolites are eliminated in milk.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-95961999000200008
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| Editor: |
Faculdade de Medicina Veterinária e Zootecnia / Universidade de São Paulo
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| Relação: |
10.1590/S1413-95961999000200008
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| Formato: |
text/html
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| Fonte: |
Brazilian Journal of Veterinary Research and Animal Science v.36 n.2 1999
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| Direitos: |
info:eu-repo/semantics/openAccess
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