Registro completo |
Provedor de dados: |
Braz. J. Vet. Res. Anim. Sci.
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País: |
Brazil
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Título: |
Syzygium cumini and the regeneration of insulin positive cells from the pancreatic duct
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Autores: |
Schossler,Deila Rosély C.
Mazzanti,Cinthia Melazzo
Luz,Sônia Cristina Almeida da
Filappi,Andreane
Prestes,Danívia
Silveira,Aron Ferreira da
Cecim,Marcelo
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Data: |
2004-08-01
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Ano: |
2004
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Palavras-chave: |
Syzygium cumini
Alloxan
Diabetes
Immunohistochemistry
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Resumo: |
Syzygium cumini is a plant that has been used in popular medicine for the treatment of insulin dependent diabetes mellitus (DMID). This study verified the effect of Syzygium cumini upon the regeneration of insulin producing cells in the pancreatic duct wall. The animals were divided into four groups, control (C), treated control (TC), diabetic control (DC) and treated diabetic (TD). An aqueous extract from Syzygium cumini bark was given by gavage in a daily dose of 1g/kg of body weight. After a thirty day period the animals were euthanized and the pancreas taken to immunohistochemical analysis. In this study, it was observed the positive staining for insulin on cells of the pancreatic duct and connective tissue in the pancreas of TD and TC animals. These results indicate that Syzygium cumini bark extract stimulates development of insulin positive cells from the pancreatic duct epithelial cells.
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Tipo: |
Info:eu-repo/semantics/article
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Idioma: |
Inglês
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Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-95962004000400003
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Editor: |
Faculdade de Medicina Veterinária e Zootecnia / Universidade de São Paulo
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Relação: |
10.1590/S1413-95962004000400003
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Formato: |
text/html
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Fonte: |
Brazilian Journal of Veterinary Research and Animal Science v.41 n.4 2004
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Direitos: |
info:eu-repo/semantics/openAccess
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