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Provedor de dados:  Ciência Rural
País:  Brazil
Título:  Congenital hepatic fibrosis associated with ascites in a nellore calf
Autores:  Gois,Daniela Dantas de
Sousa,Isabelle Vieira de
Barbosa,Francisca Maria Sousa
Silva Neto,José Ferreira da
Sampaio,Rubia Avlade Guedes
Simões,Sara Vilar Dantas
Dantas,Igor Mariz
Lucena,Ricardo Barbosa
Data:  2020-01-01
Ano:  2020
Palavras-chave:  Bos primigenius indicus
Genetic factors
Malformation
Perinatal mortality
Resumo:  ABSTRACT: Congenital hepatic fibrosis (CHF) is an autosomal recessive malformation characterized by a variable degree of fibrosis and bile duct proliferation, mainly described in people and rarely reported in bovine European breeds. In addition to liver fibrosis, this syndrome has been associated with ascites and subcutaneous edema in calves. This paper described the pathological findings of the first report of CHF in a Nelore bovine fetus. A stillborn calf was removed by cesarean section because of dystocia. At necropsy, characteristic changes of CHF were observed, such as a large increase in abdominal volume associated with hepatic fibrosis and marked subcutaneous edema. Histological examination of liver revealed periportal and port-portal islands of fibrosis separating the parenchyma into nodules of variable sizes and containing numerous abnormally shaped bile ducts. The CHF should be considered in the differential diagnosis in young calves that present with ascites.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782020000500552
Editor:  Universidade Federal de Santa Maria
Relação:  10.1590/0103-8478cr20190511
Formato:  text/html
Fonte:  Ciência Rural v.50 n.5 2020
Direitos:  info:eu-repo/semantics/openAccess
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