| Registro completo |
| Provedor de dados: |
Electron. J. Biotechnol.
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| País: |
Chile
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| Título: |
Characterization of a Gelatin/Chitosan/Hyaluronan scaffold-polymer
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| Autores: |
Enrione,Javier
Osorio,Fernando
López,Daniel
Weinstein-Oppenheimer,Caroline
Fuentes,Miguel A
Ceriani,Ricardo
Brown,Donald I
Albornoz,Fernando
Sánchez,Elizabeth
Villalobos,Patricio
Somoza,Rodrigo A
Young,Manuel E
Acevedo,Cristian A
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| Data: |
2010-09-01
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| Ano: |
2010
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| Palavras-chave: |
Chitosan
Fibrin
Gelatin
Hyaluronic acid
Scaffold
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| Resumo: |
Gelatin, chitosan and hyaluronic acid are natural components used to prepare polymeric scaffold in tissue engineering. The physical properties of these materials confer an appropriate microenvironment for cells, which can be used as a regeneration system for skin and cartilage. In this work, we prepared and characterized a Gelatin/Chitosan/Hyaluronan lyophilized-polymer. Physical properties of lyophilized-polymer changed slightly with moisture, but when polymer was totally hydrated the elasticity changed significantly. Thermophysical characterisation indicated that temperatures higher than 30ºC could modify irreversibly the polymeric matrix probably due to protein denaturation. Besides, we used the polymer as scaffold to prepare a biosynthetic-skin, reporting biological behaviour and its mechanical properties.
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| Tipo: |
Journal article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582010000500020
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| Editor: |
Pontificia Universidad Católica de Valparaíso
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| Formato: |
text/html
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| Fonte: |
Electronic Journal of Biotechnology v.13 n.5 2010
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