| Registro completo |
| Provedor de dados: |
Genet. Mol. Biol.
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| País: |
Brazil
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| Título: |
Alternative parameterizations of relatedness in whole genome association analysis of pre-weaning traits of Nelore-Angus calves
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| Autores: |
Riley,David G.
Gill,Clare A.
Herring,Andy D.
Riggs,Penny K.
Sawyer,Jason E.
Sanders,James O.
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| Data: |
2014-09-01
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| Ano: |
2014
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| Palavras-chave: |
Birth weight
Gestation length
Weaning weight
Nelore
Whole genome association
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| Resumo: |
Gestation length, birth weight, and weaning weight of F2 Nelore-Angus calves (n = 737) with designed extensive full-sibling and half-sibling relatedness were evaluated for association with 34,957 SNP markers. In analyses of birth weight, random relatedness was modeled three ways: 1) none, 2) random animal, pedigree-based relationship matrix, or 3) random animal, genomic relationship matrix. Detected birth weight-SNP associations were 1,200, 735, and 31 for those parameterizations respectively; each additional model refinement removed associations that apparently were a result of the built-in stratification by relatedness. Subsequent analyses of gestation length and weaning weight modeled genomic relatedness; there were 40 and 26 trait-marker associations detected for those traits, respectively. Birth weight associations were on BTA14 except for a single marker on BTA5. Gestation length associations included 37 SNP on BTA21, 2 on BTA27 and one on BTA3. Weaning weight associations were on BTA14 except for a single marker on BTA10. Twenty-one SNP markers on BTA14 were detected in both birth and weaning weight analyses.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572014000400007
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| Editor: |
Sociedade Brasileira de Genética
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| Relação: |
10.1590/S1415-47572014000400007
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| Formato: |
text/html
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| Fonte: |
Genetics and Molecular Biology v.37 n.3 2014
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| Direitos: |
info:eu-repo/semantics/openAccess
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