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Provedor de dados:  Genet. Mol. Biol.
País:  Brazil
Título:  Papillomaviruses: a systematic review
Autores:  Araldi,Rodrigo Pinheiro
Assaf,Suely Muro Reis
Carvalho,Rodrigo Franco de
Carvalho,Márcio Augusto Caldas Rocha de
Souza,Jacqueline Mazzuchelli de
Magnelli,Roberta Fiusa
Módolo,Diego Grando
Roperto,Franco Peppino
Stocco,Rita de Cassia
Beçak,Willy
Data:  2017-03-01
Ano:  2017
Palavras-chave:  Bovine papillomavirus (BPV)
Bovine papillomatosis
Carcinogenesis
Natural history
Resumo:  Abstract In the last decades, a group of viruses has received great attention due to its relationship with cancer development and its wide distribution throughout the vertebrates: the papillomaviruses. In this article, we aim to review some of the most relevant reports concerning the use of bovines as an experimental model for studies related to papillomaviruses. Moreover, the obtained data contributes to the development of strategies against the clinical consequences of bovine papillomaviruses (BPV) that have led to drastic hazards to the herds. To overcome the problem, the vaccines that we have been developing involve recombinant DNA technology, aiming at prophylactic and therapeutic procedures. It is important to point out that these strategies can be used as models for innovative procedures against HPV, as this virus is the main causal agent of cervical cancer, the second most fatal cancer in women.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572017000100002
Editor:  Sociedade Brasileira de Genética
Relação:  10.1590/1678-4685-gmb-2016-0128
Formato:  text/html
Fonte:  Genetics and Molecular Biology v.40 n.1 2017
Direitos:  info:eu-repo/semantics/openAccess
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