| Registro completo |
| Provedor de dados: |
74
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| País: |
Brazil
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| Título: |
Insulin-like growth factor II gene Apa I polymorphism is not associated with endometriosis susceptibility
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| Autores: |
Hsieh,Yao-Yuan
Chang,Chi-Chen
Tsai,Fuu-Jen
Peng,Ching-Tien
Yeh,Lian-Shun
Lin,Cheng-Chieh
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| Data: |
2004-01-01
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| Ano: |
2004
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| Palavras-chave: |
Endometriosis
Insulin-like growth factor
IGF-2
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| Resumo: |
Insulin-like growth factor II (IGF2) has been shown to play a role in abnormal cell growth and carcinogenesis. We investigated if the IGF2 gene Apa I polymorphism at exon 9 was associated with the susceptibility to endometriosis, analyzing 120 women with moderate/severe endometriosis and 103 controls. The genotype frequencies did not differ statistically between the endometriosis (aa = 25.4, ab = 57.4, bb = 17.2%) and control (aa = 20.8 ab = 52.8, bb = 26.4%) groups. The allele frequencies did not differ either: a = 54.1, b = 45.9% among women with endometriosis and a = 47.2, b = 52.8% in the control group. Therefore, no indication was found for an association of this polymorphism with endometriosis susceptibility.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000200006
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| Editor: |
Sociedade Brasileira de Genética
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| Relação: |
10.1590/S1415-47572004000200006
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| Formato: |
text/html
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| Fonte: |
Genetics and Molecular Biology v.27 n.2 2004
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| Direitos: |
info:eu-repo/semantics/openAccess
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