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Provedor de dados:  Genet. Mol. Biol.
País:  Brazil
Título:  Equine protease inhibitor system as a marker for the diagnosis of chronic obstructive pulmonary disease (COPD)
Autores:  Vinocur,Myriam E.
Brass,Karin E.
Caetano,Alexandre R.
Silva,Letícia F.
Silva,Aline C.
Silva,Carlos A.M.
Data:  2005-09-01
Ano:  2005
Palavras-chave:  Horse
Chronic obstructive pulmonary disease
Protease inhibitor system
Resumo:  The protease inhibitor system (PI) was investigated to ascertain if it can be used as a marker of chronic obstructive pulmonary disease (COPD) in thoroughbred horses. Serum samples were taken from healthy thoroughbreds (n = 13) and those diagnosed as having COPD (n = 24) or inflammatory airway disease (IAD, n = 38) as well as from 3,600 undiagnosed thoroughbred horses. PI allelic and genotypic frequencies were estimated using protein electrophoresis on starch and polyacrylamide gels. The four groups of horses showed high genotypic similarity and none of the observed alleles or genotypes of the equine PI system were found to be associated with COPD.
Tipo:  Info:eu-repo/semantics/other
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572005000300007
Editor:  Sociedade Brasileira de Genética
Relação:  10.1590/S1415-47572005000300007
Formato:  text/html
Fonte:  Genetics and Molecular Biology v.28 n.3 2005
Direitos:  info:eu-repo/semantics/openAccess
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