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Provedor de dados:  Genet. Mol. Biol.
País:  Brazil
Título:  Mitodepressive and clastogenic effects of aqueous extracts of the lichens Myelochroa lindmanii and Canoparmelia texana (Lecanorales, Parmeliaceae) on meristematic cells in plant bioassays
Autores:  Campos,José Marcello Salabert de
Davide,Lisete Chamma
Soares,Geraldo Luiz Gonçalves
Viccini,Lyderson Facio
Data:  2008-01-01
Ano:  2008
Palavras-chave:  Canoparmelia texana
Cytotoxicity
Mitotic index
Myelochroa lindmanii
Plant bioassays
Resumo:  The cytotoxicity effect of aqueous extracts of the lichens species Myelochroa lindmanii and Canoparmelia texana (Lecanorales, Parmeliaceae) were evaluated using meristematic cells of lettuce (Lactuca sativa) and maize (Zea mays). The seasonal effect was also evaluated. Extracts of M. lindmanii and C. texana inhibited root growth and/or percentage germination, possibly due to alterations in the cell cycle. The M. lindmanii extract showed anti-mitotic effects and blocked the cell cycle in metaphase so that c-mitosis and cells with chromosome duplication were produced. The C. texana extract appeared to hinder cell division, increasing the number of interphase cells. In addition, both extracts caused an increase in percentage of cell death. Clastogenic effects were also observed, such as sticky chromosomes, bridges, fragments and later segregation. Both lichen species are thus potential sources of biologically active substances with possible applications in biology, medicine and agronomy.
Tipo:  Info:eu-repo/semantics/other
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572008000100024
Editor:  Sociedade Brasileira de Genética
Relação:  10.1590/S1415-47572008000100024
Formato:  text/html
Fonte:  Genetics and Molecular Biology v.31 n.1 2008
Direitos:  info:eu-repo/semantics/openAccess
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