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Provedor de dados:  Genet. Mol. Biol.
País:  Brazil
Título:  The post-transcriptional gene silencing pathway in Eucalyptus
Autores:  Sassaki,Flávio Tetsuo
Campos-Pereira,Tiago
Maia,Ivan de Godoy
Data:  2005-01-01
Ano:  2005
Palavras-chave:  Gene silencing
PTGS
RNA silencing
EST
Eucalyptus
Resumo:  Post-transcriptional gene silencing (PTGS) is a conserved surveillance mechanism that identifies and cleaves double-stranded RNA molecules and their cellular cognate transcripts. The RNA silencing response is actually used as a powerful technique (named RNA interference) for potent and specific inhibition of gene expression in several organisms. To identify gene products in Eucalyptus sharing similarities with enzymes involved in the PTGS pathway, we queried the expressed sequence tag database of the Brazilian Eucalyptus Genome Sequence Project Consortium (FORESTs) with the amino acid sequences of known PTGS-related proteins. Among twenty-six prospected genes, our search detected fifteen assembled sequences encoding products presenting high level of similarity (E value < 10-40) to proteins involved in PTGS in plants and other organisms. We conclude that most of the genes known to be involved in the PTGS pathway are represented in the FORESTs database.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572005000400003
Editor:  Sociedade Brasileira de Genética
Relação:  10.1590/S1415-47572005000400003
Formato:  text/html
Fonte:  Genetics and Molecular Biology v.28 n.3 suppl.0 2005
Direitos:  info:eu-repo/semantics/openAccess
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