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Provedor de dados:  International Journal of Morphology
País:  Chile
Título:  Effects of Potentilla fulgens on Tuba Uterina in Ovariectomized Rats
Autores:  Acar,Zuat
Deger,U
Görkem,Ü
Togrul,Cihan
Deveci,E
Kaya,S
Ekinci,A
Data:  2016-06-01
Ano:  2016
Palavras-chave:  Potentilla fulgens
Ischemia-reperfusion
Tuba uterina
Rat
Resumo:  A total of 32 Wistar rats were divided into four equal groups: (I) sham, (II) ischemia, (III) reperfusion and (IV) Potentilla fulgens. In groups I and II, ovary torsion was not performed and no drug was administered. In group III, 1 h of ischemia and 2 h of reperfusion were performed and no drug was given. Group IV received 400 mg/kg/day Potentilla fulgens intraperitoneally 5 days before Ischemia-reperfusion. All the parameters were observed to be significantly decreased (P<0.05) in all the experimental groups compared to the control group. In the sections of the ischemia-reperfusion group, degeneration of epithelium, dilation of blood vessels were observed. Potentilla fulgens administration reduced the morphological changes by induced I/R; in particular, infiltration, hemorrhage and vascular dilatation were decreased. Potentilla fulgens application during torsion, it plays an important role in maintaining the epithelial structure with E-cadherin expression. We suggest that PECAM-1(CD31) are a regulator of the microvascular response of the tubal mucosa.
Tipo:  Journal article
Idioma:  Inglês
Identificador:  http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000200008
Editor:  Sociedad Chilena de Anatomía
Formato:  text/html
Fonte:  International Journal of Morphology v.34 n.2 2016
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