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Provedor de dados:  J. Venom. Anim. Toxins
País:  Brazil
Título:  THE SYSTEMIC INFLAMMATORY RESPONSE SYNDROME RELATED TO THE RELEASE OF CYTOKINES FOLLOWING SEVERE ENVENOMATION
Autores:  VORONOV,E.
APTE,R. N.
SOFER,S.
Data:  1999-01-01
Ano:  1999
Palavras-chave:  Systemic inflammatory response
Cytokines
Pro-inflammatory cytokines
Chemotactic mediators
Vasoactive mediators
Resumo:  Envenomation by insects, snakes, scorpions, and spiders involves the activation of the inflammatory system with the release and activation of pro-inflammatory cytokines, chemotactic mediators, cellular infiltration, and other vasoactive mediators. Activation of the inflammatory system and its cascade of events play a major role in the pathogenesis of envenomation, its clinical picture, and outcome. Additional clinical and laboratory studies are required to characterize the exact mechanisms by which the inflammatory system affects the pathophysiology, clinical course, and complications following envenomations. A better understanding of the involvement of the inflammatory cascade in different envenoming syndromes may have future therapeutic benefits.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301999000100002
Editor:  Centro de Estudos de Venenos e Animais Peçonhentos - CEVAP, Universidade Estadual Paulista - UNESP
Relação:  10.1590/S0104-79301999000100002
Formato:  text/html
Fonte:  Journal of Venomous Animals and Toxins v.5 n.1 1999
Direitos:  info:eu-repo/semantics/openAccess
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