| Registro completo |
| Provedor de dados: |
PAB
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| País: |
Brazil
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| Título: |
Vitamin C and endogenous cortisol in foreign-body inflammatory response in pacus
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| Autores: |
Belo,Marco Antonio de Andrade
Moraes,Julieta Rodini Engrácia de
Soares,Vando Edésio
Martins,Maurício Laterça
Brum,Camila Dantas
Moraes,Flávio Ruas de
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| Data: |
2012-07-01
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| Ano: |
2012
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| Palavras-chave: |
Piaractus mesopotamicus
Ascorbic acid
Glucocorticoid
Inflammation
Langhans cells
Multinucleated giant cells
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| Resumo: |
The objective of this work was to evaluate the effect of food supplementation with vitamin C on macrophage and multinucleated giant cell (MGC) activities of pacus at two stocking densities. The experiment was carried out in a 2x2x3 split-plot factorial arrangement with: 0 and 500 mg kg-1 vitamin C; 5 and 20 kg m-3 stocking densities; and evaluation times at 3, 6, and 12 days after the subcutaneous implantation of glass coverslips (DPI). The number of macrophages and MGC, as well as cortisol and glucose plasma levels were determined. The number of macrophages and MGC with two to five nuclei was significantly greater in fish supplemented with vitamin C at 5 kg m-3 stocking density at 3 DPI in comparison to nonsupplemented ones. The macrophage and MGC counts were lower in fish with high-plasma cortisol concentration. Supplementation with 500 mg vitamin C benefits macrophage activity on foreign-body inflammation, and high-cortisol concentration has suppressive effects on this response.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-204X2012000700019
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| Editor: |
Embrapa Secretaria de Pesquisa e Desenvolvimento
Pesquisa Agropecuária Brasileira
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| Relação: |
10.1590/S0100-204X2012000700019
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| Formato: |
text/html
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| Fonte: |
Pesquisa Agropecuária Brasileira v.47 n.7 2012
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| Direitos: |
info:eu-repo/semantics/openAccess
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