| Registro completo |
| Provedor de dados: |
Plantas Medicinales
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| País: |
Cuba
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| Título: |
Effect of Calendula officinalis infusion on indomethacin-induced gastric lesions in Wistar rats.
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| Autores: |
Bertges,Luiz Carlos
Gonçalves Felga,Ângela Maria
Piccinini Teixeira,João Batista
Magalhães Girardin Pimentel,Carolina Frade
Ornella Neves,Priscilla
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| Data: |
2006-06-01
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| Ano: |
2006
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| Palavras-chave: |
Calendula officinalis
Indomethacin
Gastric injury
Rats
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| Resumo: |
Calendula officinalis is a phytopharmaceutical believed to inhibit gastric emptying and to have hypoglycemic and gastroprotective effects. We aimed to study the putative effect of an infusion of Calendula officinalis on indomethacin-induced gastric lesions. 30 adult male Wistar rats, divided in 2 groups, received indomethacin 20 mg/kg through gavage. Group A (Study) further received 1 mL of 10 % doses of Calendula officinalis, and group B (Control) received saline, for 2 days. After this period, the stomachs were extracted and examined for lymphocytic and neutrophylic infiltrates, and for mucosal lesions such as ulcers and erosions. We concluded that Calendula officinalis did not significantly influence the appearance of such alterations in the indomethacin-injured gastric mucosa.
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| Tipo: |
Journal article
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| Idioma: |
Espanhol
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| Identificador: |
http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1028-47962006000200007
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| Editor: |
ECIMED
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| Formato: |
text/html
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| Fonte: |
Revista Cubana de Plantas Medicinales v.11 n.2 2006
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