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Petrilli,Antonio Sérgio; Cypriano,Monica; Dantas,Lenice Silva; Lee,Lúcia Martino; Luisi,Maria Flávio Augusto Vercillo; Silva,Katia Veronica Torres B.; Pereira,Carlos Alberto Pires. |
BACKGROUND: The empirical use of antibiotic treatments is widely accepted as a means to treat cancer patients in chemotherapy who have fever and neutropenia. Intravenous monotherapy, with broad spectrum antibiotics, of patients with a high risk of complications is a possible alternative. METHODS: We conducted a prospective open-label, randomized study of patients with lymphoma or leukemia who had fever and neutropenia during chemotherapy. Patients received either monotherapy with ticarcillin/clavulanic acid (T) or ceftriaxone plus amikacin (C+A). RESULTS: Seventy patients who presented 136 episodes were evaluated, 68 in each arm of the study. The mean neutrophil counts at admission were 217cells/mm³ (T) and 201cells/mm³ (C+A). The mean duration of... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Fever; Neutropenia; Leukemia; Lymphoma; Ticarcillin; Ceftriaxone. |
Ano: 2003 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000200003 |
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