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Registros recuperados: 79 | |
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TIZIOTO, P. C.; DECKER, J. E.; TAYLOR, J. F.; SCHNABEL, R. D.; MUDADU, M. de A.; MOURAO, G. B.; COUTINHO, L. L.; THOLON, P.; SONSTEGARD, T. S.; ROSA, A. do N.; ALENCAR, M. M. de; TULLIO, R. R.; MEDEIROS, S. R. de; NASSU, R. T.; FEIJO, G. L. D.; SILVA, L. O. C. da; TORRES JUNIOR, R. A. de A.; SIQUEIRA, F.; HIGA, R. H.; REGITANO, L. C. de A.. |
Meat quality traits are economically important because they affect consumers' acceptance, which, in turn, influences the demand for beef. However, selection to improve meat quality is limited by the small numbers of animals on which meat tenderness can be evaluated due to the cost of performing shear force analysis and the resultant damage to the carcass. Genome wide-association studies for Warner-Bratzler shear force measured at different times of meat aging, backfat thickness, ribeye muscle area, scanning parameters [lightness, redness (a*), and yellowness] to ascertain color characteristics of meat and fat, water-holding capacity, cooking loss (CL), and muscle pH were conducted using genotype data from the Illumina BovineHD BeadChip array to identify... |
Tipo: Separatas |
Palavras-chave: GWAS; QTL; Beef cattle; Zebu. |
Ano: 2013 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/982207 |
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MOKRY, F. B.; BUZANSKAS, M. E.; MUDADU, M. de A.; GROSSI, D. do A.; HIGA, R. H.; VENTURA, R. V.; LIMA, A. O. de; SARGOLZAEI, M.; MEIRELLES, S. L. C.; SCHENKEL, F. S.; SILVA, M. V. G. B.; NICIURA, S. C. M.; ALENCAR, M. M. de; MINARI, D. P.; REGITANO, L. C. de A.. |
Abstract. Background: The development of linkage disequilibrium (LD) maps and the characterization of haplotype block structure at the population level are useful parameters for guiding genome wide association (GWA) studies, and for understanding the nature of non-linear association between phenotypes and genes. The elucidation of haplotype block structure can reduce the information of several single nucleotide polymorphisms (SNP) into the information of a haplotype block, reducing the number of SNPs in a coherent way for consideration in GWA and genomic selection studies. Results: The maximum average LD, measured by r2 varied between 0.33 to 0.40 at a distance of < 2.5 kb, and the minimum average values of r2 varied between 0.05 to 0.07 at distances... |
Tipo: Separatas |
Palavras-chave: Composite; Desequilíbrio de ligação; Genome wide association studies; Halplotype block; Linjage disequilibirium; Polimorfismo de nucleotídeo único.; Gado de corte.; Beef cattle; Linkage disequilibrium; Single nucleotide polymorphism.. |
Ano: 2014 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1006604 |
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MUDADU, M. de A.; PORTO-NETO, L. R.; MOKRY, F. B.; TIZIOTO, P. C.; OLIVEIRA, P. S. N.; TULLIO, R. R.; NASSU, R. T.; NICIURA, S. C. M.; THOLON, P.; ALENCAR, M. M. de; HIGA, R. H.; ROSA, A. do N.; FEIJO, G. L. D.; FERRAZ, A. L. J.; SILVA, L. O. C. da; MEDEIROS, S. R. de; LANNA, D. P.; NASCIMENTO, M. L.; CHAVES, A. S.; SOUZA, A. R. D. L.; PACKER, I. U.; TORRES JUNIOR, R. A. de A.; SIQUEIRA, F.; MOURÃO, G. B.; COUTINHO, L. L.; REVERTER, A.; REGITANO, L. C. de A.. |
Nelore is the major beef cattle breed in Brazil with more than 130 million heads. Genome-wide association studies (GWAS) are often used to associate markers and genomic regions to growth and meat quality traits that can be used to assist selection programs. An alternative methodology to traditional GWAS that involves the construction of gene network interactions, derived from results of several GWAS is the AWM (Association Weight Matrices)/PCIT (Partial Correlation and Information Theory). With the aim of evaluating the genetic architecture of Brazilian Nelore cattle, we used high-density SNP genotyping data (~770,000 SNP) from 780 Nelore animals comprising 34 half-sibling families derived from highly disseminated and unrelated sires from across Brazil.... |
Tipo: Artigo de periódico |
Palavras-chave: Genome-wide association studies; Association Weight Matrices; Partial Correlation and Information Theory; Gene; Genética; Gado Nelore; Gado de corte; Genótipo; Genotyping; Genotype; Nellore; Beef cattle; Genetic resources. |
Ano: 2016 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1059898 |
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SOUZA, M.; NICIURA, S. C. M.; TIZIOTO, P.; IBELLI, A. M. G.; GASPARIN, G.; MALAGO JUNIOR, W.; MUDADU, M. de A.; BARIONI JUNIOR, W.; COUTINHO, L.; REGITANO, L. C. de A.. |
Tipo: Separatas |
Palavras-chave: KCNJ11; Gene; Cattle. |
Ano: 2013 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/980666 |
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SOMAVILLA, A. L.; REGITANO, L. C. de A.; ROSA, G. J. M.; MOKRY, F. B.; MUDADU, M. de A.; TIZIOTO, P. C.; OLIVEIRA, P. S. N. de; SOUZA, M. M. de; COUTINHO, L. L.; MUNARI, D. P.. |
Nelore is the most economically important cattle breed in Brazil, and the use of genetically improved animals has contributed to increase beef production efficiency. The Brazilian beef feedlot industry has grown considerably in the last decade, so the selection of animals with higher growth rates on feedlot has become quite important. Genomic selection could be used to reduce generation intervals and improve the rate of genetic gains. The aim of this study was to evaluate the prediction of genomic estimated breeding values for average daily gain in 718 feedlot-finished Nelore steers. Analyses of three Bayesian model specifications (Bayesian GBLUP, BayesA, and BayesCπ) were performed with four genotype panels (Illumina BovineHD BeadChip, TagSNPs,... |
Tipo: Artigo de periódico |
Palavras-chave: Genomic selection; Bos taurus indicus; Growth. |
Ano: 2017 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1070097 |
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MOKRY, F. B.; BUZANSKAS, M. E.; MUDADU, M. de A.; GROSSI, D. do A.; HIGA, R. H.; VENTURA, R. V.; LIMA, A. O. de; SARGOLZAEI, M.; MEIRELLES, S. L. C.; SCHENKEL, F. S.; SILVA, M. V. G. B. da; NICIURA, S. C. M.; ALENCAR, M. M. de; MINARI, D. P.; REGITANO, L. C. de A.. |
Abstract. Background: The development of linkage disequilibrium (LD) maps and the characterization of haplotype block structure at the population level are useful parameters for guiding genome wide association (GWA) studies, and for understanding the nature of non-linear association between phenotypes and genes. The elucidation of haplotype block structure can reduce the information of several single nucleotide polymorphisms (SNP) into the information of a haplotype block, reducing the number of SNPs in a coherent way for consideration in GWA and genomic selection studies. Results: The maximum average LD, measured by r2 varied between 0.33 to 0.40 at a distance of < 2.5 kb, and the minimum average values of r2 varied between 0.05 to 0.07 at distances... |
Tipo: Artigo de periódico |
Palavras-chave: Polimorfismo de nucleotídeo único; Genome wide association studies; Desequilíbrio de ligação; Gado de corte; Beef cattle; Single nucleotide polymorphism; Linkage disequilibrium. |
Ano: 2014 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1003463 |
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SOMAVILLA, A. L.; HIGA, R. H.; MUDADU, M. de A.; ALENCAR, M. M. de; REGITANO, L. C. de A.. |
A identificação de regiões do genoma que controlam características de interesse econômico e que estejam sob seleção é possível por conta da disponibilidade da genotipagem em plataformas de altas densidades de polimorfismos de único nucleotídeo (SNPs). A busca por assinaturas de seleção avalia, principalmente, altas e não usuais frequências alélicas dos loci adjacentes às mutações favoráveis. Com o objetivo de detectar evidências de assinaturas de seleção recente no genoma de bovinos da raça Nelore, foram genotipados 796 indivíduos com o chip Illumina BovineHD BeadChip, que possui mais de 777 mil SNPs e, posteriormente, inferida a fase de ligação dos SNPs e a reconstrução dos blocos de desequilíbrio de ligação (haplótipos). A detecção de assinaturas de... |
Tipo: Anais e Proceedings de eventos |
Palavras-chave: Desequilíbrio de ligação; Genotipagem.; Bos Indicus.; Zebu; Genotype; Single nucleotide polymorphism; Linkage disequilibrium. |
Ano: 2012 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/946719 |
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DINIZ, M. R. V.; PAIVA, A. L. B.; GUERRA-DUARTE, C.; NISHIYAMA JÚNIOR, M. Y.; MUDADU, M. de A.; OLIVEIRA, U. de; BORGES, M. H.; YATES, J. R.; JUNQUEIRA-DE-AZEVEDO, I. de. |
Abstract. Phoneutria nigriventer is one of the largest existing true spiders and one of the few considered medically relevant. Its venom contains several neurotoxic peptides that act on different ion channels and chemical receptors of vertebrates and invertebrates. Some of these venom toxins have been shown as promising models for pharmaceutical or biotechnological use. However, the large diversity and the predominance of low molecular weight toxins in this venom have hampered the identification and deep investigation of the less abundant toxins and the proteins with high molecular weight. Here, we combined conventional and next-generation cDNA sequencing with Multidimensional Protein Identification Technology (MudPIT), to obtain an in-depth panorama of... |
Tipo: Artigo de periódico |
Palavras-chave: Proteômica; Transcriptoma; Phoneutria nigriventer; Proteomics; Transcriptomics. |
Ano: 2018 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1102272 |
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BRESSANI, F. A.; TIZIOTO, P. C.; GIGLIOTI, R.; MEIRELLHES, S. L. C.; COUTINHO, L. L.; BENVENUTI, C. L.; MALAGO JUNIOR, W.; MUDADU, M. de A.; VIEIRA, L. S.; ZAROS, L. G.; CARRILHO, E.; REGITANO, L. C. de A.. |
Tipo: Separatas |
Palavras-chave: Cytokine; Gastrointestinal infection.; Capra Hircus.; Single nucleotide polymorphism.. |
Ano: 2014 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1002812 |
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TIZIOTO, P.; DECKER, J.; TAYLOR, J.; SCHNABEL, R.; MUDADU, M. de A.; COUTINHO, L. L.; MOURÃO, G. B.; SONSTEGARD, T.; ROSA, A. do N.; ALENCAR, M. M. de; TULLIO, R. R.; MEDEIROS, S. R.; NASSU, R. T.; FEIJO, G. L. D.; SIQUEIRA, F.; REGITANO, L. C. de A.. |
Tipo: Separatas |
Palavras-chave: Genome map; Tagging; Characterization.; Cattle.. |
Ano: 2013 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/989023 |
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KASARAPU, P.; PORTO NETO, L. R.; FORTES, M. R. S.; LEHNERT, S. A.; MUDADU, M. de A.; COUTINHO, L. L.; REGITANO, L. C. de A.; GEORGE, A.; REVERTER, A.. |
Numerical approaches to high-density single nucleotide polymorphism (SNP) data are often employed independently to address individual questions. We linked independent approaches in a bioinformatics pipeline for further insight. The pipeline driven by heterozygosity and Hardy-Weinberg equilibrium (HWE) analyses was applied to characterize Bos taurus and Bos indicus ancestry. We infer a gene co-heterozygosity network that regulates bovine fertility, from data on 18,363 cattle with genotypes for 729,068 SNP. Hierarchical clustering separated populations according to Bos taurus and Bos indicus ancestry. The weights of the first principal component were subjected to Normal mixture modelling allowing the estimation of a gene?s contribution to the Bos taurus-Bos... |
Tipo: Artigo de periódico |
Palavras-chave: Hardy-Weinberg equilibrium; Bos Indicus; Bos Taurus. |
Ano: 2017 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1074938 |
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TIZIOTO, P. C.; TAYLOR, J. F.; DECKER, J. E.; GROMBONI, C. F.; MUDADU, M. de A.; SCHNABEL, R. D.; COUTINHO, L. L.; MOURÃO, G. B.; NASSU, R. T.; DONATONI, F. A. B.; THOLON, P.; SONSTEGARD, T. S.; ALENCAR, M. M. de; TULLIO, R. R.; REECY, J. M.; NOGUEIRA, A. R. de A.; REGITANO, L. C. de A.. |
Tipo: Separatas |
Palavras-chave: Fe; GWAS.; Bos Indicus.. |
Ano: 2014 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/997999 |
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CESAR, A. S. M.; REGITANO, L. C. de A.; LANNA, D. P. D.; POLETI, M. D.; KOLTES, J. E.; REECY, J. M.; FRITZ-WATERS, E.; KRAMER, L.; GARRICK, D.; MUDADU, M. de A.; TULLIO, R. R.; COUTINHO, L. L.. |
Tipo: Anais e Proceedings de eventos |
Palavras-chave: Nelore.; Gado nelore; Gado de Corte.; Nellore. |
Ano: 2016 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1057056 |
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MOKRY, F. B.; HIGA, R. H.; MUDADU, M. de A.; LIMA, A. O. de; MEIRELLES, S. L. C.; SILVA, M. V. G. B.; CARDOSO, F. F.; OLIVEIRA, M. M. de; URBINATI, I.; NICIURA, S. C. M.; TULLIO, R. R.; ALENCAR, M. M. de; REGITANO, L. C. de A.. |
Meat quality involves many traits, such as marbling, tenderness, juiciness, and backfat thickness, all of which require attention from livestock producers. Backfat thickness improvement by means of traditional selection techniques in Canchim beef cattle has been challenging due to its low heritability, and it is measured late in an animal?s life. Therefore, the implementation of new methodologies for identification of single nucleotide polymorphisms (SNPs) linked to backfat thickness are an important strategy for genetic improvement of carcass and meat quality. |
Tipo: Artigo de periódico |
Palavras-chave: Machine learning; Tropical composition cattle; Bovino; Lipid metabolism; Subcutaneous fat. |
Ano: 2013 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/959968 |
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Registros recuperados: 79 | |
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