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Registros recuperados: 26 | |
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Tahtinen, Petri; Guella, Graziano; Saielli, Giacomo; Debitus, Cecile; Hnawia, Edouard; Mancini, Ines. |
Arsenicin A (C3H6As4O3) was isolated from the New Caledonian poecilosclerid sponge Echinochalina bargibanti, and described as the first natural organic polyarsenic compound. Further bioguided fractionation of the extracts of this sponge led us to isolate the first sulfur-containing organic polyarsenicals ever found in Nature. These metabolites, called arsenicin B and arsenicin C, are built on a noradamantane-type framework that is characterized by an unusual As-As bonding. Extensive NMR measurements, in combination with mass spectra, enabled the assignment of the structure for arsenicin B (C3H6As4S2) as 2. The scarcity of arsenicin C and its intrinsic chemical instability only allowed the collection of partial spectral data, which prevented the full... |
Tipo: Text |
Palavras-chave: Antibacterial; Arsenical; Calculated NMR spectrum; Density functional theory; Natural products; NMR spectroscopy; Structure elucidation; Sulfur metabolite. |
Ano: 2018 |
URL: https://archimer.ifremer.fr/doc/00469/58051/72242.pdf |
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Falaise, Charlotte; Francois, Cyrille; Travers, Marie-agnes; Morga, Benjamin; Haure, Joel; Tremblay, Rejean; Turcotte, Francois; Pasetto, Pamela; Gastineau, Romain; Hardivillier, Yann; Leignel, Vincent; Mouget, Jean-luc. |
The search for novel compounds of marine origin has increased in the last decades for their application in various areas such as pharmaceutical, human or animal nutrition, cosmetics or bioenergy. In this context of blue technology development, microalgae are of particular interest due to their immense biodiversity and their relatively simple growth needs. In this review, we discuss about the promising use of microalgae and microalgal compounds as sources of natural antibiotics against human pathogens but also about their potential to limit microbial infections in aquaculture. An alternative to conventional antibiotics is needed as the microbial resistance to these drugs is increasing in humans and animals. Furthermore, using natural antibiotics for... |
Tipo: Text |
Palavras-chave: Biological activity; Antimicrobial; Antibacterial; Antifungal; Antiviral; Biological activity; Haslea; Microalgae; Sustainable aquaculture. |
Ano: 2016 |
URL: http://archimer.ifremer.fr/doc/00349/46052/45719.pdf |
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Alhajj,MS; Qasem,MAA; Nabi,AR Jar El; Al-Mufarrej,SI. |
ABSTRACT This study investigated the in-vitro antibacterial and fungicidal activities of three crude extracts of Illicium verum (absolute methanol, 50% methanol and aqueous extracts) against two Gram-positive bacteria (Staphylococcus aureus and Listeria monocytogenes), two Gram-negative bacteria (Escherichia coli and Salmonella Arizona), and two fungi (Aspergillus fumigatus and Aspergillus niger). The antibacterial action was measured using an agar disk diffusion test, and the minimum inhibitory concentrations (MICs) and minimum bactericidal concentrations (MBCs) were determined. The fungicidal activity of the star anise extracts was assessed by the agar disk diffusion test, and poisoned food techniques, and the MICs and minimum fungicidal concentrations... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Illicium verum; Antibacterial; Antifungal. |
Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2019000100330 |
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Picinin,Lidia Cristina Almeida; Toaldo,Isabela Maia; Hoff,Rodrigo Barcellos; Souza,Fernando Nogueira; Leite,Mônica Oliveira; Fonseca,Leorges Moraes; Diniz,Soraia Araújo; Silva,Marcos Xavier; Haddad,João Paulo Amaral; Cerqueira,Mônica Maria Oliveira Pinho; Bordignon-Luiz,Marilde Terezinha. |
ABSTRACT Veterinary drug residues in bulk tank milk are important to all sectors of the dairy chain because they are one of the major factors which determine the safety of the final product. This study attempted to identify milk quality parameters that are associated with the occurrence of veterinary drug residues using multivariate principal component analysis (PCA). A total of 132 raw milk samples were collected from 45 dairy farms in the state of Minas Gerais - Brazil and analyzed for 42 analytes, including pyrethroids, macrocyclic lactones and antibacterials, using liquid chromatography coupled with mass spectrometry in tandem mode and gas chromatography with electron capture detection. Out of the 132 milk samples, 40 samples tested positive for at... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Pesticide; Anthelmintic; Antibacterial; Macrocyclic lactone; Food safety. |
Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-90162017000300195 |
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Cruz,Carolinie Batista Nobre da; Pieri,Fabio Alessandro; Carvalho-Zilse,Gislene Almeida; Orlandi,Patrícia Puccinelli; Nunes-Silva,Carlos Gustavo; Leomil,Luciana. |
Honeys are described possessing different properties including antimicrobial. Many studies have presented this activity of honeys produced by Apis mellifera bees, however studies including activities of stingless bees honeys are scarce. The aim of this study was to compare the antimicrobial activity of honeys collected in the Amazonas State from Melipona compressipes, Melipona seminigra and Apis mellifera against Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Chromobacterium violaceum, and Candida albicans. Minimum inhibitory concentrations were determined using the agar dilution method with Müller-Hinton agar (for bacteria) or Saboraud agar (for yeast). Staphylococcus aureus and E. faecalis were inhibited by all honeys at concentrations... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Melipona; Antibacterial; Antifungal; Natural products; Functional food. |
Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672014000200015 |
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Silva,Saulo L. da; Oliveira,Viviane Guedes de; Yano,Tomomasa; Nunomura,Rita de Cássia Saraiva. |
Endopleura uchi (Huber) Cuatrec. is an Amazon species traditionally used as treatment for inflammations and female disorders. Bergenin was isolated from ethyl acetate fraction of bark of E. uchi by using column chromatography over sephadex LH-20 and then silica gel 60 flash. Its structure was identified on the basis of its NMR spectra. The antimicrobial activity of bergenin and fractions of methanol extract of E. uchi were evaluated against ATCC microorganisms (Escherichia coli, Salmonella enteritidis, Pseudomonas aeruginosa, Enterococcus faecalis, Staphylococcus aureus, Candida albicans, C. guilliermondii, Aspergillus flavus, A. nidulans). Clinically isolated strains of all of these microorganisms, along with C. tropicalis, A. niger, Shigella sonnei,... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antibacterial; Antifungal; Candida; Humiriaceae; Uxi-amarelo. |
Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672009000100019 |
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PINTO,NÍCOLAS C.C.; SILVA,JUCÉLIA B.; MENEGATI,LAURA M.; GUEDES,MARIA CLARA M.R.; MARQUES,LUCAS B.; SILVA,THIAGO P. DA; MELO,ROSSANA C.N. DE; SOUZA-FAGUNDES,ELAINE M. DE; SALVADOR,MARCOS J.; SCIO,ELITA; FABRI,RODRIGO L.. |
ABSTRACT This study aimed to further investigate the cytotoxicity against tumor cell lines and several bacterial strains of Annona squamosa and its mode of action. Methanol extracts of A. squamosa leaves (ASL) and seeds (ASS) were used. ASL showed significant antibacterial activity against S. aureus, K. pneumoniae and E. faecalis with MIC values of 78, 78 and 39 µg/mL respectively. Moreover, ASL exhibited significant biofilm disruption, rapid time dependent kinetics of bacterial killing, increased membrane permeability and significantly reduced the cell numbers and viability. Regarding the cytotoxicity against tumor cell lines, ASS was more active against Jurkat and MCF-7 cells, with CI50 1.1 and 2.1 µg/mL, respectively. ASL showed promising activity... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Alkaloids; Annona squamosa; Antibacterial; Citotoxicity; Herbal medicine. |
Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000502053 |
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J. SIMÃO,MARIELA; J.S. BARBOZA,THIAGO; G. VIANNA,MARCELA; GARCIA,RENATA; MANSUR,ELISABETH; P.R. IGNACIO,ANA CLAUDIA; PACHECO,GEORGIA. |
Abstract Passiflora species are well known for their common use in popular medicine for the treatment of several diseases, such as insomnia, anxiety, and hysteria, in addition to their anti-inflammatory, antioxidant, analgesic and antibacterial potential. However, few data about the chemical composition and the medicinal potential of in vitro derived materials are available. Therefore, the goal of this work was to compare, for the first time, the phytoconstituents of in vitro derived materials of four Passiflora species, and evaluate the antibacterial potential of their extracts against 20 Gram-positive and negative strains. Chromatographic analysis indicated the presence of saponins in roots extracts from all studied species, whereas leaf extracts... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antibacterial; Chromatography; Flavonoids; Passiflora; Saponins. |
Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000602805 |
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ASSIS,FELIPE V. DE; SIQUEIRA,FLÁVIA L.; GONÇALVES,ISABELA E.; LACERDA,RAFAEL P.; NASCIMENTO,RAFAELA A.; ARAÚJO,STHÉFANE G.; ANDRADE,JÉSSICA T.; HERRERA,KARINA M.S.; LIMA,LUCIANA A.R.S.; FERREIRA,JAQUELINE M.S.. |
ABSTRACT The antibacterial activity of plant extracts of the Lamiaceae family was evaluated against clinical isolates of multi-resistant Gram-negative bacteria by broth microdilution technique. Promising results were obtained considering that all extracts were active for at least two bacterial species with MIC ranging from 0.5 to 2.0 mg/mL. |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antibacterial; Clinical isolates; Lamiaceae extracts; Multidrug-resistant. |
Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000401665 |
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RÍOS-CHÁVEZ,PATRICIA; PEREZ-GONZALEZ,JORDY; SALGADO-GARCIGLIA,RAFAEL; RAMÍREZ-CHÁVEZ,ENRIQUE; MOLINA-TORRES,JORGE; MARTINEZ-TRUJILLO,MIGUEL; CARREON-ABUD,YAZMIN. |
Abstract: This study evaluates the antibacterial, cytotoxic activities, and phytochemical composition, of Callistemon citrinus, Hibiscus rosa-sinensis and Plumbago auriculata leaves and flowers, three ornamental plants in Mexico. However, in other countries offers a range of other uses. Ethanol extracts of C. citrinus leaf and flower presented stronger antibacterial activity than the extracts obtained from the other two plants. C. citrinus leaf showed low cytotoxicity (LC50 <600 µg/mL) on the brine shrimp test, whereas the ethanol extracts of H. rosa-sinensis and P. auriculata leaves showed no cytotoxic activity. Flower extracts obtained from the three plants did no exhibit cytotoxicity. GC-MS analysis revealed that the ethanol extract of P. auriculata... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antibacterial; Artemia salina; Callistemon citrinus; Cytotoxic; Lupeol. |
Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300611 |
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SANTOS,TÁSSIA L.A. DOS; QUEIROZ,RAPHAEL F.; SAWAYA,ALEXANDRA C.H.F.; LOPEZ,BEGOÑA GIMENEZ-CASSINA; SOARES,MILENA B.P.; BEZERRA,DANIEL P.; RODRIGUES,ANA CAROLINA B.C.; PAULA,VANDERLÚCIA F. DE; WALDSCHMIDT,ANA MARIA. |
ABSTRACT Geopropolis is a special type of propolis produced by stingless bees. Several pharmacological properties have been described for different types of geopropolis, but there have been no previous studies of the geopropolis from Melipona mondury. In this study, we investigated the antioxidant, antibacterial, and antiproliferative activities of M. mondury geopropolis, and determined its chemical profile. The antioxidant activity was determined using in vitro ABTS·+, ·DPPH, and β-carotene/linoleic acid co-oxidation methods. The antibacterial activity was determined using a microdilution method with Pseudomonas aeruginosa, Staphylococcus aureus, and methicillin-resistant S. aureus. The antiproliferative effect was determined in tumor cell lines using the... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antibacterial; Antioxidant; Antiproliferative; Geopropolis; Melipona mondury. |
Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000502247 |
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Pieri,F.A.; Silva,V.O.; Souza,C.F.; Costa,J.C.M.; Santos,L.F.; Moreira,M.A.S.. |
O objetivo deste estudo foi identificar a atividade inibitória de óleos de copaíba sobre o crescimento dos micro-organismos: Shigella flexneri, Klebsiella pneumoniae, Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa, Citrobacter freundi, Staphylococcus aureus, Actinobacillus pleuropneumoniae e Haemophilus parasuis. Foi realizado um teste de difusão em ágar com duas soluções a 10% de óleos de copaíba obtidos de duas diferentes espécies de copaíba (Copaifera officinalis e C. langsdorffii) e um controle negativo com tween 80 e água. Os isolados clínicos de H. parasuis e A. pleuropneumoniae foram incubados em microaerofilia. Os resultados mostraram três espécies Gram-negativas inibidas por ambas as soluções de óleo de copaíba: E. coli, P. aeruginosa... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Phytotherapics; Antimicrobial; Antibacterial; Copaifera. |
Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352012000100037 |
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Paudel,Babita; Datta Bhattarai,Hari; Prasad Pandey,Durga; Seoun Hur,Jae; Gyu Hong,Soon; Kim,Il-Chan; Han Yim,Joung. |
A total of twenty four lichen species belonging to six families were collected from mountainous region of Nepal. The methanol extracts of each species were tested for antimicrobial and antioxidant activitiesin vitro. It was found that extracts of twenty one lichen species were active againstB. subtilis and seven species were active againstS. aureus. Similarly, in DPPH assay, three speciesPeltigera sp.,Cladonia sp., andCanoparmelia sp. showed comparable activity with commercial standard, BHA. In ABTS+ assay, extracts ofParmoterma sp.,Ramalina sp.,Peltigera sp. andCladonia sp. showed stronger activity than ascorbic acid. The observed data after comparison with previously published reports indicated that the high altitude lichens contain stronger antioxidant... |
Tipo: Journal article |
Palavras-chave: Antibacterial; Antioxidant; Nepal lichens; Free radicals. |
Ano: 2012 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000400010 |
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Challouf,Rafika; Trabelsi,Lamia; Ben Dhieb,Rym; El Abed,Omeya; Yahia,Ali; Ghozzi,Khamissa; Ben Ammar,Jihen; Omran,Hela; Ben Ouada,Hatem. |
The aim of this work was to evaluate the cytotoxicity of Arthrospira platensis Extracellular Polymeric Substances (EPS) for colon cancer and kidney cell lines. Results showed that EPS were free from cytotoxic effects. A variety of solvents were assessed for their ability to extract the bioactive ingredients from EPS. Methanol gave the highest yield (75.75%) than other solvents. The extracts were tested for activities against a collection of Gram+/- bacteria. The methanol extract exhibited a more potent activity than the other organic extracts, whereas the aqueous extract was active against Staphylococcus epidermis (Gram+) and Salmonella typhimurium (Gram-). Finally, The extracts were also tested for the antioxidant activity, using the Trolox Equivalent... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cyanobacteria; Exoplysaccharides; Cytotoxicity; Antibacterial; Antioxidant; Activity. |
Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000400024 |
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Zmantar,Tarek; Ben Slama,Rihab; Fdhila,Kais; Kouidhi,Bochra; Bakhrouf,Amina; Chaieb,Kamel. |
Abstract Objectives: This study aims to investigate the antimicrobial and the anti-biofilm activities of Lactobacillus plantarum extract (LPE) against a panel of oral Staphylococcus aureus (n = 9) and S. aureus ATCC 25923. The in vitro ability of LPE to modulate bacterial resistance to tetracycline, benzalchonium chloride, and chlorhexidine were tested also. Methods: The minimum inhibitory concentrations (MICs) and the minimal bactericidal concentrations of Lactobacillus plantarum extract, tetracycline, benzalchonium chloride and clohrhexidine were determined in absence and in presence of a sub-MIC doses of LPE (1/2 MIC). In addition, the LPE potential to inhibit biofilm formation was assessed by microtiter plate and atomic force microscopy assays.... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antibacterial; Staphylococcus aureus; Biofilm; Antibiotics; Synergetic; Lactobacillus. |
Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000100027 |
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Araújo,Sthéfane G.; Alves,Lucas F.; Pinto,Maria Eduarda A.; Oliveira,Graziela T.; Siqueira,Ezequias P.; Ribeiro,Rosy I. M. A.; Ferreira,Jaqueline M. S.; Lima,Luciana A. R. S.. |
Bacterial infections cause thousands of deaths in the world every year. In most cases, infections are more serious because the patient is already weakened, and often, the bacteria are already resistant to the antibiotics used. Counterparting this negative scenario, the interest in medicinal plants as an alternative to the synthetic antimicrobial drugs is blossoming worldwide. In the present work, we identified the volatile compounds of ethanol extracts of Melissa officinalis, Mentha sp., Ocimum basilicum, Plectranthus barbatus, and Rosmarinus officinalis by gas chromatography/mass spectrometry (GC/MS). Also was evaluated antimicrobial activity of ethanol extracts against 6 bacteria of clinical interest, and was tested the interaction of these extracts with... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Lamiaceae; Antibacterial; Ethanol extracts; Volatile compounds; Streptomycin. |
Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000400026 |
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Registros recuperados: 26 | |
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