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Registros recuperados: 8
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Nuclear entropy, angular second moment, variance and texture correlation of thymus cortical and medullar lymphocytes: Grey level co-occurrence matrix analysis Anais da ABC (AABC)
PANTIC,IGOR; PANTIC,SENKA; PAUNOVIC,JOVANA; PEROVIC,MILAN.
Grey level co-occurrence matrix analysis (GLCM) is a well-known mathematical method for quantification of cell and tissue textural properties, such as homogeneity, complexity and level of disorder. Recently, it was demonstrated that this method is capable of evaluating fine structural changes in nuclear structure that otherwise are undetectable during standard microscopy analysis. In this article, we present the results indicating that entropy, angular second moment, variance, and texture correlation of lymphocyte nuclear structure determined by GLCM method are different in thymus cortex when compared to medulla. A total of 300 thymus lymphocyte nuclei from 10 one-month-old mice were analyzed: 150 nuclei from cortex and 150 nuclei from medullar regions of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Texture analysis; GLCM matrix; CD4; CD8; Gene.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652013000301063
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CD4+ cell counts in patients with different clinical manifestations of tuberculosis BJID
Davoudi,Setareh; Rasoolinegad,Mehrnaz; Younesian,Masoud; Hajiabdolbaghi,Mahboubeh; Soudbakhsh,Abdolreza; Jafari,Sirous; EmadiKouchak,Hamid; Mehrpouya,Morteza; Lotfi,Hossein.
Tuberculosis is the prototype of infections that require a cellular immune response for their control. It has been shown that CD4+ T-lymphocytes are most important in the protective response against Mycobacterium tuberculosis. CD8+ T-lymphocytes are also important for effective T-cell immune response. This study compares CD4+ and CD8+ baseline values in patients with different manifestations of tuberculosis. CD4+ and CD8+ in three groups of patients with tuberculosis (pulmonary, lymphadenitis, meningitis/milliary involvement) and a group of healthy volunteers were enumerated using flowcytometry. Twenty-six patients with pulmonary tuberculosis, 10 with adenitis, 16 with meningitis or milliary tuberculosis and 16 healthy volunteers entered the study. Mean...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Tuberculosis; Mycobacterium tuberculosis; CD4.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000600008
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Low variation in initial CD4 cell count in a HIV referral center, in Salvador, Brazil, from 2002 to 2015 BJID
Pereira,Marcela Fonseca; Luz,Estela; Martins Netto,Eduardo; Barbosa,Manoel Henrique Fonseca; Brites,Carlos.
ABSTRACT Early initiation of antiretroviral therapy increases the likelihood of effective immune restoration, quality of life, and greater life expectancy for HIV-infected individuals. We evaluated the evolution of mean CD4+ cells count at diagnosis of HIV/AIDS in Salvador, Brazil from 2002 to 2015. We identified HIV/AIDS patients older than 18 years with diagnosis of HIV infection from 2002 to 2015, who had their first laboratory evaluation at Complexo Hospitalar Prof. Edgard Santos, Federal University of Bahia. Initial mean CD4+ cells count and age, over time were evaluated. A total of 1801 patients randomly selected individuals were included in the analysis. Overall mean CD4+ count at diagnosis in the whole period was 279 ± 265, varying from 191 in 2015...
Tipo: Info:eu-repo/semantics/other Palavras-chave: HIV/AIDS; CD4; Antiretroviral therapy.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000300245
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Immune restoration in human immunodeficiency virus and hepatitis C virus coinfected patients after highly active antiretroviral therapy BJID
Antonello,Vicente Sperb; Appel-da-Silva,Marcelo Campos; Kliemann,Dimas Alexandre; Santos,Breno Riegel; Tovo,Cristiane Valle.
OBJECTIVE: To evaluate the influence of hepatitis C virus on immunological and virological responses after highly active antiretroviral therapy initiation in human immunodeficiency virus/hepatitis C virus coinfected patients compared to monoinfected human immunodeficiency virus-infected patients. METHODS: The study enrolled 65 human immunodeficiency virus-1-infected subjects who initiated highly active antiretroviral therapy and attended follow-up visits over 48 weeks from 2008 to 2010. They were grouped based on hepatitis C virus-RNA results. Virological and immunological responses were monitored at baseline and at the end of weeks 12, 24, 36, and 48. RESULTS: There were 35 human immunodeficiency virus monoinfected and 30 human immunodeficiency...
Tipo: Info:eu-repo/semantics/article Palavras-chave: HIV; Hepatitis C; Coinfection; HAART; CD4; Immunological response.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000500007
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Reference range for T lymphocytes populations in blood donors from two different regions in Brazil BJID
Torres,A.J.L.; Angelo,A.L.D.; Netto,E.M.; Sampaio,G.P.; Souza,D.F.C.; Inocêncio,L.A.; Lemos,J.A.R.; Brites,C..
This study defined the normal variation range for different subsets of T-lymphocyte cells count in two different Brazilian regions. We analysed the T-lymphocytes subpopulations (CD3+, CD4+, CD8+) in blood donors of two Brazilian cities, located in North (Belem, capital state of Para, indian background) and Northeast (Salvador, capital state od Bahia, African background) regions of Brazil. Results were compared according to gender, stress level (sleep time lower than 8 hours/day), smoking, and alcohol intake. Lymphocytes subpopulations were measured by flow cytometry. Five hundred twenty-six blood donors from two Brazilians cities participated in the study: 450 samples from Bahia and 76 samples from Pará. Most (60%) were men, 59% reported alcohol intake,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: CD4; CD8; Blood donors; Reference values; Brazil.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000300013
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Onset of opportunistic infections in patients co-infected by HTLV-1 and HIV-1, with high CD4+ cells count BJID
Regis,Catarin; Oliveira,Adriano; Brites,Carlos.
We reported two cases of patients with coinfection by human immunodeficiency virus (HIV) type 1 and human T-cell lymphotropic virus (HTLV) type I who developed opportunistic infections despite of relatively high CD4+ cells count. These cases showed clinical evidence to consider an earlier antiretroviral treatment for coinfected patientes regardless CD4+ cells counts.
Tipo: Info:eu-repo/semantics/report Palavras-chave: HIV-1/HTLV-1 co-infection; Opportunistic infections; CD4.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000400014
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Depression and diagnosis of neurocognitive impairment in HIV-positive patients BJMBR
Pinheiro,C.A.T.; Souza,L.D.M.; Motta,J.V.S.; Kelbert,E.F.; Souza,M.S.; Martins,C.S.R.; Coelho,F.M.C.; Pinheiro,K.A.T.; Pinheiro,R.T..
Neurocognitive impairment (NCI) is frequently observed in patients infected with human immunodeficiency virus (HIV) and results from the compromise of subcortical brain structures by the virus. The manifestations of NCI range from asymptomatic impairment to dementia. In addition to cognitive impairment resulting from HIV infection, other factors such as depression are associated with the loss of cognitive functions. The aim of this study was to estimate the prevalence of NCI in HIV-positive patients in a city in southern Brazil and to establish possible associations for the prevalence of NCI with HIV-related and other risk factors. This cross-sectional study of HIV-positive outpatients was conducted in a specialized care service in the city of Pelotas in...
Tipo: Info:eu-repo/semantics/article Palavras-chave: AIDS; Depression; Neurocognitive; HIV; HAND; CD4.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016001000704
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Control of CD4 gene expression: connecting signals to outcomes in T cell development BJMBR
Sarafova,S.D.; Siu,G..
The control of CD4 gene expression is essential for proper T lymphocyte development. Signals transmitted from the T-cell antigen receptor (TCR) during the thymic selection processes are believed to be linked to the regulation of CD4 gene expression during specific stages of T cell development. Thus, a study of the factors that control CD4 gene expression may lead to further insight into the molecular mechanisms that drive thymic selection. In this review, we discuss the work conducted to date to identify and characterize the cis-acting transcriptional control elements in the CD4 locus and the DNA-binding factors that mediate their function. From these studies, it is becoming clear that the molecular mechanisms controlling CD4 gene expression are very...
Tipo: Info:eu-repo/semantics/article Palavras-chave: CD4; Gene expression; Silencer; T cell; Development.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000700001
Registros recuperados: 8
Primeira ... 1 ... Última
 

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