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	Provedor de dados International Journal of Morphology (1) Autor Araújo Filho,José Candido de (1) Assis,Thiago de Oliveira (1) Maia,Maria Bernadete de Sousa (1) Palavra-chave Fetal Programming (1) Inflammation (1) Systematic review (1) Wistar Rats (1) Tipo do documento Journal article (1) Ano 2010 (1) País Chile (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 59 Primeira ... 1 2 3 ... Última Leptospirose bovina: cuidados preventivos evitam prejuízo e garantem saúde do rebanho. Infoteca-e CAVALCANTE, F. A.. A leptospirose bovina é uma doença infecciosa, causada por bactérias do gênero leptospira, podendo ser encontrada em todo o território nacional. Na atividade pecuária, além da adoção de novas tecnologias, é importante implementar um calendário sanitário e o controle de doenças na esfera reprodutiva para garantir sanidade aos rebanhos bovinos. Existe tratamento para a leptospirose bovina, mas o criador deve adotar os cuidados necessários e buscar ajuda com profissional capacitado, que, a partir das variantes sorológicas identificadas nos rebanhos, indicará as medidas de controle e o tratamento adequado. Tipo: Artigo de divulgação na mídia (INFOTECA-E) Palavras-chave: Métoto de controle; Ganado bovino; Enfermedades animales; Métodos de control; Bovinocultura; Doença Animal; Leptospirose; Transferência de Tecnologia; Cattle; Animal diseases; Control methods; Leptospirosis; Technology transfer. Ano: 2021 URL: http://www.infoteca.cnptia.embrapa.br/infoteca/handle/doc/1132497 Serología positiva a Leptospira interrogans, serovar cynopteri en caninos de la Ciudad de Buenos Aires, Argentina InVet Tealdo,M.S; Romero,G.N; Autrey,C.D; Samartino,L. La Leptospirosis es una enfermedad infectocontagiosa, producida por una bacteria del género Leptospira, que ataca indistintamente al hombre y a animales domésticos y silvestres. El agente puede vivir y reproducirse en aguas de ríos, arroyos, lagos, aguas estancadas, etc. Es una patología polimorfa. Los caninos pueden actuar como fuente de infección para el hombre debido al estrecho contacto que se desarrolla entre ambos. Tradicionalmente al género Leptospira se lo considera integrado por dos especies: L. interrogans (formas patógenas) y L. biflexa (abarca formas saprófitas). Estas especies a su vez, se dividen en serogrupos y serovares. Entre junio y septiembre de 2003 se recolectaron 110 muestras de suero de caninos que concurrieron al Instituto de... Tipo: Info:eu-repo/semantics/article Palavras-chave: Leptospirosis; Prevalencia; Cynopteri; Canino. Ano: 2007 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1668-34982007000100007 Evaluación clínica, bioquímica y hematológica de caninos seropositivos a distintos serovares de Leptospira interrogans InVet Gualtieri,CAS; Carlín,C; Peralta,l; Peirone,C; Gattarello,V; Marc,L; Molteni,H; Arestegui,MB; François,S. La leptospirosis es una zoonosis de distribución mundial que afecta a diferentes especies animales. La principal fuente de infección es la contaminación del medio ambiente con orina de los animales infectados. En caninos y en el hombre el diagnóstico es dificultoso debido a la variada signología clínica que presenta. El objetivo de este estudio fue evaluar las alteraciones clínicas, bioquímicas y hematológicas más frecuentes en caninos seropositivos a diferentes serovares de Leptospira interrogans. Se estudiaron 44 caninos con signos clínicos compatibles y serología positiva y 25 caninos clínicamente sanos y seronegativos. Se realizó una evaluación clínica completa y se obtuvieron muestras de sangre con y sin anticoagulante, para realizar diagnóstico... Tipo: Info:eu-repo/semantics/article Palavras-chave: Leptospira interrogans; Leptospirosis; Canino; Diagnóstico; Bioquímica. Ano: 2012 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1668-34982012000200001 Leptospira spp. infection in sheep herds in southeast Brazil J. Venom. Anim. Toxins incl. Trop. Dis. Barbante,Priscila; Shimabukuro,Fabio H; Langoni,Helio; Richini-Pereira,Virgínia B; Lucheis,Simone B. Background With the aim of studying Leptospira spp. infection in sheep herds, blood samples and respective kidney and liver fragments were collected from 100 animals from twenty different properties during slaughter at a meat company in the Sorocaba region, São Paulo state, southeast Brazil. The microscopic agglutination test (MAT) was performed with 29 strains of Leptospira spp. To identify the agent in the liver and kidney, 100 samples of each tissue were submitted to culture in Fletcher medium and analyzed by the polymerase chain reaction (PCR) for Leptospira spp.Results MAT detected 23 samples serologically positive for one or more Leptospira spp. serovars and significantly more for Autumnalis. Eight (4%) samples were positive in culture (four kidneys... Tipo: Info:eu-repo/semantics/article Palavras-chave: Leptospirosis; Ovine; Serology; Culture; PCR. Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992014000200325 Cytokine and antibody production during murine leptospirosis J. Venom. Anim. Toxins incl. Trop. Dis. Marinho,M.; Silva,C.; Lima,V. M. F.; Peiró,J. R.; Perri,S. H. V.. The aim of the present study was to investigate the kinetics of humoral and cellular responses during leptospirosis. We observed that the presence of tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) was associated with antibody production and bacterial recovery, and the compromising of both TNF-alpha and IL-6 in the immunopathogenesis of leptospirosis during an experimental infection of BALB/c mice inoculated with Leptospira interrogans serovar Canicola was verified. Results showed higher levels of TNF-alpha and IL-6 in the initial phase of infection, in which the greatest bacterial clearance was observed. However, when the bacterial recovery was compared with the kinetics of the production of antibodies, the results revealed a kinetics... Tipo: Info:eu-repo/semantics/article Palavras-chave: Cytokines; Cellular immune response; BALB/c mice; Leptospirosis. Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992006000400006 Interactions between environment, wild animals and human leptospirosis J. Venom. Anim. Toxins incl. Trop. Dis. Ullmann,LS; Langoni,H. Leptospirosis, a worldwide distributed zoononis caused by bacteria of the genus Leptospira (antigenically classified into serovars), may be direct or indirectly transmitted through infected urine or environment. Several domestic and wild animals are leptospirosis reservoirs. The disease presents occupational character since it is widely reported in professionals that work in humid environments - such as sewage workers and fishermen - and in places where rodents or susceptible animals are found, like slaughterhouses and veterinary clinics. In developing countries, outbreaks are related to lack of sanitation, overcrowding in inadequate housing and climatic conditions. In developed countries, sporadic cases occur in aquatic recreational activities including... Tipo: Info:eu-repo/semantics/article Palavras-chave: Leptospira spp.; Leptospirosis; Public health; Occupational disease; Recreational disease. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000200002 Role of cytokines, NO, and H2O2 on the immunopathology of Leptospirosis in genetically selected mice J. Venom. Anim. Toxins incl. Trop. Dis. Marinho,M.; Langoni,H.; Oliveira,S. L.; Lima,V. M. F.; Peiró,J. R.; Perri,S. H. V.; Carreira,R.. Immune response to leptospirosis is mainly humorally mediated, and involves opsonization of leptospires for phagocytosis by macrophages and neutrophils. However, some aspects are still unknown. For a more detailed analysis of the cellular immune response to leptospirosis infection, trials were carried out in order to determine the hydrogen peroxide and nitric oxide (H2O2 and NO) production stimulated or not by Interferon-gamma. The participation of some specific cytokines, such as Tumor Necrosis Factor-alpha (TNF-alpha); Interferon-gamma (IFN-gamma); Interleukin-6 (IL-6); and Interleukin-4 (IL-4), in the immunopathology of this infection was also investigated. For this purpose, we analyzed the supernatant from peritoneal macrophage cell culture and the... Tipo: Info:eu-repo/semantics/article Palavras-chave: Leptospirosis; Cytokines; Cellular immunity. Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992005000200009 Tissue apoptosis in mice infected with Leptospira interrogans serovar Icterohaemorrhagiae J. Venom. Anim. Toxins incl. Trop. Dis. Marinho,Márcia; Táparo,Cilene Vidovix; Oliveira Júnior,Itamar S.; Perri,Silvia Helena Venturoli; Cardoso,Tereza Cristina. Tipo: Info:eu-repo/semantics/article Palavras-chave: Leptospirosis; Caspases; Programmed cell death; Mice; Inflammatory response. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992015000100326 Anti-leptospirosis agglutinins in Brazilian capybaras (hydrochoerus hydrochaeris) J. Venom. Anim. Toxins incl. Trop. Dis. Langoni,Helio; Kuribara,Ivone Yumi; Correa,Ana Paula Ferreira Lopes; Ullmann,Leila Sabrina; Sánchez,Gabriela Pacheco; Lucheis,Simone Baldini. Abstract Background The interest in commercial use of wild animals is increasing, especially regarding raising of capybaras. Although this wild species is potentially lucrative for the production of meat, oil and leather, it is suggested as a probable reservoir of leptospires. Methods Due to the economic importance of this species and the lack of studies concerning leptospirosis, the presence of anti-leptospirosis agglutinins was assayed in 55 serum samples of capybaras (Hydrochoerus hydrochaeris) from commercial and experimental breeding flocks located in São Paulo state, Paraná state, and Rio Grande do Sul state, Brazil. Samples were obtained through cephalic or femoral venipunction (5 to 10 mL). Microscopic agglutination test was used according to... Tipo: Info:eu-repo/semantics/article Palavras-chave: Leptospirosis; Capybaras; Hydrochoerus hydrochaeris; Serologic evaluation; Zoonosis. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992016000100304 TNF-α and IL-6 immunohistochemistry in rat renal tissue experimentaly infected with Leptospira interrogans serovar Canicola J. Venom. Anim. Toxins incl. Trop. Dis. Marinho,M; Monteiro,CMR; Peiró,JR; Machado,GF; Oliveira-Júnior,IS. Leptospirosis is a public health problem worldwide and its etiology remains unclear. Its pathogenesis involves a complex interaction between host and infecting microorganism. The inflammatory reaction that controls the infection process also underscores many pathophysiological events occurring in leptospirosis. We investigated the presence of tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) in renal tissues by immunohistochemical and histopathological examination in animals experimentally inoculated with Leptospira serovar Canicola. All the tests were carried out 2, 7, 14, 21 or 28 days after inoculation. Although TNF-α and IL-6 had been detected in tissues throughout the observation period, these cytokines appeared more intensely during the... Tipo: Info:eu-repo/semantics/article Palavras-chave: Leptospirosis; Immunohistochemistry; IL-6; TNF-α; Mice. Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992008000300012 Leptospirosis: animal and public health aspects MV&Z Langoni, Helio. Leptospirosis is a zoonotic di ease with acute to cronic evolution, affecting domestic and wild animals, also cold-blooded species. The spirochetes from Leptospira genera are the aetiologic agent, found in environment, living a saprofhyte life too. It's an important public health concern, linked to socio-economical problems, flood, and occupacional exposure in slaughterhouse employees, water and agricultural activities. This paper gives informations abouts the leptospirosis agents, with the new classification, epidemiological aspects from susceptible species, with the disease prevalence. Are show pathological, diagnostic and clinical aspects, and the prafilatic measurements. Tipo: Info:eu-repo/semantics/article Palavras-chave: Leptospirosis; Animal health; Public health leptospirose; Saúde animal; Saúde pública. Ano: 1999 URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/3379 Diagnóstico de leptospirosis en casos de abortamento em bovinos MV&Z Silva, R.; Delpiazzo, R.; Schelotto, F.; Varela, G.; Meny, P.; Quintero, J.; Menéndez, C.; Romero, A.; Ríos, C.; Rodriguez, E.. La leptospirosis bovina es una enfermedad reproductiva muy importante en los bovinos ya que causa problemas de infertilidad en los rodeos de cría y considerables pérdidas económicas. Además es una zoonosis ocupacional de incidencia alta en personal de campo y veterinarios, por exposición directa o indirecta a la orina de vacas, abortamientos, fetos al momento del parto, cesáreas o durante el diagnóstico de gestación. El objetivo de este artículo es la descripción de casos de abortamientos producidos por leptospirosis. Los animales afectados fueron vacas y vaquillonas, produciéndose abortamientos en el 44% de los vientres preñados. Las vacas abortadas que se examinaron clínicamente presentaron retención de placenta y leve decaimiento. Los abortos se... Tipo: Info:eu-repo/semantics/article Palavras-chave: Leptospirosis; Abortos; Bovinos. Ano: 2016 URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/32162 Estudio retrospectivo de agentes infecciosos que afectan la reproducción bovina en el departamento del Caquetá, Colombia Rev Salud Anim. Motta Giraldo,J.L; Waltero García,Indira; Abeledo,Ma. Antonia; Fernández,O. Se analizaron los resultados de las investigaciones serológicas para brucelosis, leptospirosis, herpesvirus bovino -1 (HVB-1), diarrea viral bovina (DVB) y Neospora caninum, de los casos enviados al laboratorio por los propietarios de los hatos bovinos en el departamento del Caquetá, Colombia, en los años 1999 - 2009. La información fue obtenida de la base de datos del ICA (Instituto Colombiano Agropecuario), seccional Caquetá. Se consideraron las variables: agentes infecciosos, años, municipios, zonas y sexos. El porcentaje promedio de brucelosis fue de 6,4% y los mayores valores se obtuvieron para herpesvirus bovino-1 (HVB-1). En el caso de Neospora, las investigaciones comenzaron en 2007 y en los 3 años solo se trabajaron 36 muestras, de las cuales 12... Tipo: Journal article Palavras-chave: Brucellosis; Leptospirosis; Herpesvirus bovino-1; Diarrea viral bovina; Neospora caninum. Ano: 2012 URL: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0253-570X2012000300004 ESTUDIO RETROSPECTIVO DE LEPTOSPIROSIS EN LA POBLACIÓN HUMANA Y ANIMAL EN MUNICIPIOS HABANEROS ENTRE 1987 - 2006 Rev Salud Anim. Fabré,Y; Suárez,Yolanda; Rodríguez,O; Martínez,Hilda; Feraud,Dania; Cruz,Miriam; López,María de los Ángeles. Con el objetivo de caracterizar la situación de la leptospirosis en la población humana y animal se realizó un análisis retrospectivo a partir de los archivos Municipales y Provinciales del Instituto de Medicina Veterinaria Municipal , su red de diagnóstico y los Servicios de Salud Pública de idéntico nivel. Se determinaron los reportes de casos de leptospirosis en la población humana y animal desde el año1993 - 2006 en ocho municipios habaneros. Se calculó el valor porcentual, la frecuencia relativa y la prevalencia de la enfermedad, atendiendo a los números de reportes de casos por población (humana y animal), años, especies, zonas (rural y urbana) y el serovar de Leptospira involucrado. La mayor prevalencia de la enfermedad la presentó la población... Tipo: Journal article Palavras-chave: Leptospirosis; Prevalencia; Zoonosis. Ano: 2010 URL: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0253-570X2010000300007 LA LEPTOSPIROSIS CANINA Y SU PROBLEMÁTICA EN MÉXICO Rev Salud Anim. Luna,A.M.A; Moles,C.L.P; Gavaldón,R.D; Nava,V.C; Salazar,G.F. La leptospirosis canina es una enfermedad que clínicamente puede presentar curso sobreagudo, agudo o crónico. Es de difícil diagnóstico por la gran variedad de manifestaciones clínicas, ya que no involucra necesariamente ictericia, se manifiesta principalmente en forma subclínica, por lo que son más frecuentes los hallazgos serológicos, que la manifestación de la enfermedad. En casos crónicos, puede ocasionar la muerte por insuficiencia renal y hepática. Los animales recuperados quedan en estado de portador en el que diseminan a la bacteria a través de la orina, representando un factor de riesgo y un importante eslabón en la cadena epidemiológica de la leptospirosis humana. La situación de la leptospirosis canina en México es poco conocida y es conveniente... Tipo: Journal article Palavras-chave: Leptospira; Leptospirosis; Perros; Canideos; Canicola; Icterohaemorrhagiae. Ano: 2008 URL: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0253-570X2008000100001 Implicaciones de las prácticas agropecuarias urbanas y rurales sobre la transmisión de la leptospirosis Agrociencia Hernández-Rodríguez,Patricia; Gómez,A. Patricia; Villamil,L. Carlos. Resumen Las modificaciones en las prácticas agropecuarias y las condiciones climáticas y geográficas del trópico, asociadas con una amplia diversidad biológica, favorecen la propagación de enfermedades, la aparición de nuevos patógenos, o la reaparición de algunos ya controlados. Por lo tanto, y debido a que la leptospirosis es una zoonosis emergente asociada con inundaciones en zonas urbanas y rurales, que afecta mínimo 160 especies animales, y que el agua es un vehículo importante de transmisión, es necesario un trabajo interdisciplinar que minimice su presentación, y el impacto sobre la salud humana, animal y sobre el ecosistema (“Una Salud”). Por consiguiente, el objetivo de este ensayo fue analizar las implicaciones de las prácticas agropecuarias... Tipo: Info:eu-repo/semantics/article Palavras-chave: Agricultura urbana y rural; Limitantes de salud; Leptospirosis; Una salud. Ano: 2017 URL: http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S1405-31952017000700725 Prevalence and spatial analysis of antileptospiral agglutinins in dairy cattle - Microregion of Sete Lagoas, Minas Gerais, 2009/2010 Arq. Bras. Med. Vet. Zootec. Nicolino,R.R.; Lopes,L.B.; Rodrigues,R.O.; Teixeira,J.F.B.; Haddad,J.P.A.. The aim of this study was to evaluate the seroprevalence of leptospirosis in the dairy herds from Minas Gerais, Brazil, during the years 2009 and 2010. A total of 2,915 serum samples were collected from the lactating cows of 151 properties in eleven municipalities located in the Sete Lagoas region. The Microscopic Agglutination Test was used to detect antileptospiral agglutinins. An individual animal prevalence of 20.7% (95% CI = 17.1% - 24.3%) and a herd prevalence of 80.8% (95% CI = 73.8% = 87.7%) were determined. The most prevalent serovars were hardjoprajitno at 19.4%; hardjoprajitnostrain Norma at 17.4%; and hardjo-bovis at 17.4%. These results show the significance of the hardjo serovar in bovine leptospirosis cases in Minas Gerais. Tipo: Info:eu-repo/semantics/article Palavras-chave: Leptospirosis; Prevalence; Sete Lagoas; Dairy cattle; Brazil. Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352014000300648 Leptospirosis research: fast, easy and reliable enumeration of mobile leptospires Biol. Res. SCHREIER,STEFAN; TRIAMPO,WANNAPONG; DOUNGCHAWEE,GALAYANEE; TRIAMPO,DARAPOND; CHADSUTHI,SUDARAT. Leptospirosis caused by Leptospira interrogans is the most widespread zoonosis and a major public health problem worldwide. Based on light-scattering and absorption, quantification of leptospires using UV-VIS spectroscopy was used as an indirect counting technique by measuring the optical density and comparing this to automated direct counting using a counting chamber in combination with imaging and analyzing software. Two serovars, Bangkok and Copenhagenii, from log-phase growth were used for the establishment of standard curves. They were found to be linear and slightly different in gradient for each serovar. The ease, rapidity, and reliability of these two adapted and optimized counting techniques may provide a useful alternative enumeration technique... Tipo: Journal article Palavras-chave: Leptospirosis; Leptospira; Enumeration; Spectroscopy; Indirect counting. Ano: 2009 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602009000100001 Contribuição ao Conhecimento da Incidência de Leptospiras em Murídeos, Caninos e Suínos no Paraná BABT Enrietti,Marcos Augusto. This research carried out in the city of Curitiba took us to the following conclusions: 1) In the main zone of Curitiba city the leptospirosis index among the rats captured reached 78 percent. This index represent the greatest incidence verified till the present moment in Brazil. 2) The ‘Rattus norwegicus’ was the chief species among those rats (96 percent). 3) According to the results presented, the culturing methods are preferable to the inoculating one. 4) The combination of these two simple methods is more advantageous in the leptospira research. Tipo: Info:eu-repo/semantics/article Palavras-chave: Leptospirosis; Weil disease; Rattus norwegicus. Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132001000500015 Production of leptospiral LipL32 antigen in Pichia pastoris and its use in an enzyme-linked immunosorbent assay BABT Monte,Leonardo Garcia; Leal,Fernanda Munhoz Dos Anjos; Hartwig,Daiane Drawanz; Vasconcellos,Sílvio Arruda; Brihuega,Bibiana; Dellagostin,Odir Antonio; Hartleben,Cláudia Pinho. The production of recombinant LipL32 protein using Escherichia coli has been used extensively for the development of vaccines and diagnostic tests for leptospirosis. However, E. coli has demonstrated limitations, including low yield and lack of post-translational modifications. In this study, rLipL32 was produced in eukaryotic expression system (Pichia pastoris) and evaluated the antigen by enzyme-linked immunosorbent assay (ELISA). The yield obtained from the culture supernatant reached 270 mg/L and ELISA showed an accuracy of 95.34%. In summary, the production of rLipL32 using P. pastoris did not impair the antigenic characteristics of this antigen and ensured its use for detecting the leptospiral antibodies in swine sera. Tipo: Info:eu-repo/semantics/article Palavras-chave: Pichia pastoris; LipL32; ELISA; Leptospirosis. Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132014000300007 Registros recuperados: 59 Primeira ... 1 2 3 ... Última

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