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Registros recuperados: 225 | |
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Gross,Andressa Verdum; Stolz,Eveline Dischkaln; Müller,Liz Girardi; Rates,Stela Maris Kuze; Ritter,Mara Rejane. |
ABSTRACT Among the medicinal purposes for which plants have been used is the treatment of “nerves". The objective of this study was to search for species of plants used in the state of Rio Grande do Sul (South Brazil) for the relief of symptoms related to central nervous system (CNS) disorders. Twenty-seven ethnobotanical studies were compiled, in which a total of 94 species were cited. The five most cited species were Cymbopogon citratus (81.5 %), Melissa officinalis (77.7 %), Aloysia citriodora (66.6 %), Matricaria chamomilla (62.9 %) and Passiflora edulis (51.8 %). Scientific studies have corroborated the popular use of these plants as sedatives, but most studies are preclinical and very few have been clinical (M. chamomilla and M. officinalis), and... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Central nervous system disorders; Ethnobotany; Popular medicine; Sedative; Toxicity. |
Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-33062019000200269 |
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Carrillo, Marcela Pedraza; Universidade Estadual Paulista “Júlio de Mesquita Filho”; Bovi, Thaís de Souza; Universidade Estadual Paulista “Júlio de Mesquita Filho”; Negrão, Adriana Fava; Universidade Estadual Paulista “Júlio de Mesquita Filho”; Orsi, Ricardo de Oliveira; Universidade Estadual Paulista “Júlio de Mesquita Filho”. |
Agrochemicals on crop cultivated areas is a source of contamination for bees and may cause physiological and behavioral disorders and mortality. The LD50 of the pesticides fipronil and imidacloprid was determined and their effect on the learning behavior of Apis mellifera L. honeybee evaluated. LD50 was determined by the ingestion of contaminated food with different concentrations of insecticide concentrations: Fipronil (0, 0.8, 0.4, 0.2, 0.1 and 0.05 µg bee-1) and imidacloprid (0, 0.4, 0.2, 0.1, 0.05 and 0.025 µg bee-1). The method of proboscis extension reflection (PER) and learning through citral odor evaluated their responses to food stimulation. LD50 obtained were 0.28 ± 0.11 and 0.10 ± 0.04 µg bee-1 for fipronil and imidacloprid, respectively. The... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Beekeeping; Toxicity; Lethal dose Agrochemical fipronil; Beekeeping; Toxicity; Lethal dose. |
Ano: 2013 |
URL: http://periodicos.uem.br/ojs/index.php/ActaSciAnimSci/article/view/18683 |
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Furlanetto, Patrícia de Nazaré Cardoso; Unidade de Ensino Superior Ingá; Novakowski, Gisele Caroline; Universidade Estadual de Maringá/Unidade de Ensino Superior Ingá; Correa, Edmar Antônio; Unidade de Ensino Superior Ingá. |
Herein, we present results from an ethnobotanical study (from February to August 2009) aiming the improvement and rationalization of medical practices, based on popular use of plants. We applied semi-structured interviews to 220 families from the urban area of Mandaguaçu municipality, Paraná State. During the interviews we recorded the following information about the used plants: common name; plant part used; method of preparation; collection site; therapeutic indication, and known adverse effects. Additionally, we compared the data obtained in the interviews with the literature in order to identify contradiction in use and application. Among the interviewees, 90% use medicinal plants, obtained especially from the backyards. We recorded 44 ethnobotanical... |
Tipo: Etnobotânica |
Palavras-chave: 2.03.00.00-0 medicinal plants; Folk knowledge; Toxicity; Adverse effects Botânica. |
Ano: 2012 |
URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/9306 |
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Shiogiri, Natália Sayuri; UNESP; Carraschi, Silvia Patrícia; Unesp; Cubo, Patrícia; Unesp; Schiavetti, Bárbara Lopes; Unesp; Cruz, Claudinei da; Unesp; Pitelli, Robinson Antonio; Unesp. |
Aquatic macrophytes are important components of aquatic ecosystems, but these plants have become a problem due to their occurrence in different regions. Some studies aimed to demonstrate the effectiveness of herbicides to control these macrophytes; however, few studies report the possible ecotoxicological effects. The objective of this study was to estimate the acute toxicity (LC (I)50;96h) and assess water quality variables for glyphosate in the Rodeo® formulation, Aterbane® BR surfactant and mixtures of glyphosate + 0.5% and 1.0% of surfactant, for the guaru fish (Phallocerus caudimaculatus). The guaru was exposed to increasing concentrations of glyphosate and a mixture of glyphosate + 0.5 and 1.0% of surfactant. The mixture of glyphosate... |
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Palavras-chave: Tropical fish; Toxicity; Herbicide tropical fish; Toxicity; Herbicide. |
Ano: 2010 |
URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/6795 |
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ManiRam,Prasad; Abhishek,Kumar; Diwakar,Mishra; Sunil K,Srivastav; Ajai K,Srivastav. |
An acute toxicity test was performed by using a four-day static renewal test to determine the LC50 value of aqueous extract of Euphorbia royleana latex for the freshwater fsh, Heteropneustes fossilis. The LC50 values, their upper and lower confdence limits and slope functions were calculated. The LC50 values for aqueous extract of Euphorbia royleana latex at various exposure periods were 7.758 mg/L for 24 h, 5.847 mg/L for 48 h, 4.474 mg/L for 72 h and 3.090 mg/L for 96 h. The regression coeffcient showed that there was signifcant negative correlation between exposure time and different LC values. Hence, it is concluded that the concentration to produce toxicity of latex of Euphorbia royleana is comparable and close to the concentration to produce toxicity... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Fish; Euphorbia royleana; Toxicity; LC50. |
Ano: 2010 |
URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1851-37432010000100001 |
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García-Mateos,Rosario; Soto-Hernández,Marcos; Zavala-Chávez,Fernando; Kite,Geofrey. |
Abstract The purpose of this study was to compare the alkaloid profile in different tissues analyzed by GC/MS and to contribute to the ecological knowledge of Calia secundiflora (patol). Samples of leaves, root and seeds of patol (mescal bean) were collected and field information was recorded in the States of Hidalgo and Querétaro, México, using the point-centered quarted method. Species dominance was calculated (value of importance) and the two locations were compared in species richness, similarity index, and soil data. Seventeen species of plants were found in Hidalgo and 21 in Querétaro; Flourensia resinosa and patol dominated the vegetation in Hidalgo, while patol and Dodonaea viscosa dominated in Querétaro. The profile of the quinolizidine alkaloids... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Dodonaea viscosa; Flourensia resinosa; Ecology; Fabaceae; Habitat; Toxicity. |
Ano: 2007 |
URL: http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S1405-31952007000200161 |
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Ferreira,Paulo M.P.; Carvalho,Ana F.U.; Farias,Davi F.; Cariolano,Nara G.; Melo,Vânia M.M.; Queiroz,Maria G.R.; Martins,Alice M.C.; Machado-Neto,Joaquim G.. |
In this work, biological effects of the water extract of Moringa oleifera seeds (WEMOS) were assessed on eggs and 3rd instar larvae of Aedes aegypti and on its toxicity upon laboratory animals (Daphnia magna, mice and rats). Crude WEMOS showed a LC50 value of 1260µg/mL, causing 99.2 ± 2.9% larvae mortality within 24 h at 5200µg/mL, though this larvicidal activity has been lost completely at 80ºC/10 min. WEMOS did not demonstrate capacity to prevent egg hatching. After extensive dialyses of the crude WEMOS into watersoluble dialyzable (DF) and nondyalizable (NDF) fractions, only DF maintained its efficacy to kill larvae. Acute toxicity evaluations on daphnids (EC50 of 188.7µg/mL) and mice (LD50 of 446.5 mg/kg body weight) pointed out to low toxicity.... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Aedes aegypti; Daphnia magna; Larvicidal activity; Moringa oleifera seeds; Toxicity. |
Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652009000200007 |
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CARVALHO,FRANCISCO R.S.; MOURA,ANTONIO G.; RODRIGUES,GARDENIA F.; NUNES,NARCIA M.F.; LIMA,DAISY J.B.; PESSOA,CLAUDIA; COSTA,MARCILIA P.; FERREIRA,PAULO M.P.; PERON,ANA PAULA. |
ABSTRACT The objective of this study was to evaluate the antiproliferative, cytotoxic and genotoxic potential of salty liquid synthetic flavorings of Butter, Cheddar Cheese and Onion. The antiproliferative potential (2.9-1500 µg/mL) was assessed by MTT assay after 72h using the human tumor lines SF-295 (glioblastoma), OVCAR-8 (ovarian), HCT-116 (colon) and HL-60 (promyelocytic leukemia) and primary cultures of murine Sarcoma 180 (S180) and peripheral blood mononuclear cells (PBMC). Allium cepa bulbs were exposed to growing respective doses (1 mL and 2 mL). Only Butter and Cheddar flavorings revealed cytotoxic activity on cancer cells, with IC50 values ranging from 125.4 µg/mL (Cheddar - HCT-116) to 402.6 µg/mL (Butter - OVCAR-8). Butter flavoring was the... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Food additives; Allium cepa; Antiproliferative action; Neoplasic cells; Toxicity. |
Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000401419 |
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ARAÚJO,ÉVERTON JOSÉ FERREIRA DE; OLIVEIRA,GUILHERME ANTÔNIO LOPES DE; SOUSA,LÍVIA QUEIROZ DE; BOLZANI,VANDERLAN DA SILVA; CAVALHEIRO,ALBERTO JOSÉ; TOME,ADRIANA DA ROCHA; PERON,ANA PAULA; SANTOS,ANDRÉ GONZAGA DOS; CITÓ,ANTONIA MARIA DAS GRAÇAS LOPES; PESSOA,CLÁUDIA; FREITAS,RIVELILSON MENDES DE; FERREIRA,PAULO MICHEL PINHEIRO. |
ABSTRACTCasearia sylvestris Swartz is a medicinal plant widely distributed in Brazil. It has anti-inflammatory, antiulcer and antitumor activities and is popularly used to treat snakebites, wounds, diarrhea, flu and chest colds. Its leaves are rich in oxygenated tricyclic cis-clerodane diterpenes, particulary casearins. Herein, we evaluated the antioxidant activities of a fraction with casearins (FC) isolated from C. sylvestrisand histological changes on the central nervous system and livers of Mus musculus mice. Firstly, in vitro studies (0.9, 1.8, 3.6, 5.4 and 7.2 μg/mL) revealed EC50 values of 3.7, 6.4 and 0.16 µg/mL for nitrite, hydroxyl radical and TBARS levels, respectively. Secondly, FC (2.5, 5, 10 and 25 mg/kg/day) was intraperitoneally... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Clerodane diterpenes; Casearia sylvestris; Antioxidant; Morphological changes; Toxicity. |
Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000401791 |
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Santos,Rudã F.B.; Dias,Henrique M.; Fujimoto,Rodrigo Y.. |
The objective of this work was to evaluate the acute toxicity of formalin and histopathological effects on the Amazon ornamental fish, bluespotted coridora (Corydoras melanistius). A randomized design was used, with ten concentrations of formalin (40%) (0, 3, 6, 12, 25, 50, 100, 150, 200 and 250mg.L-1) with four replicates and five fish per container (3L) in static system for 96 hours. The moribund fish were killed and fixed in 10% formalin to proceed the histopathological analysis of gill, liver and kidney. At the end of this experiment the following mortality rates (%) were obtained in increasing order of exposure: 0, 0, 0, 0, 0, 65, 85, 100, 100 and 100%. The lethal concentration 50% (LC50-96h (I)) estimated was 50.76 mg.L-1 with regression of y =... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Lethal concentration; Corydora; Formaldehyde; Toxicity; Histology; Amazon. |
Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652012000400014 |
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Humeres,Eduardo; Da Cruz,Ivana B.M.; Oliveira,Alice K. de. |
Effect of age, sex and time exposure of Anastrepha fraterculus (Wied.) to toxicity of fenthion was evaluated. The age of the flies was important to the appearance of the first intoxication symptoms; males and females of reproductive ages (30 and 60 days-old, respectively) were less susceptible to insecticide than flies in the remainder ages (four and 120 days-old). The effect of body weight on insect intoxication was not detected. LT 50 biossay with fenthion (varying from 3-7 minutes) showed a lower susceptibility of males than females at all ages. Adults of both sexes and 30 days-old submitted to continuous and discontinuous exposure to fenthion did not show toxic cumulative effect of the insecticide. The statistical analysis suggests a possible general... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Insecta; Fruit-fly; Insecticide; Toxicity. |
Ano: 1999 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0301-80591999000200011 |
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Queiroz-Neto,A.; D'Angelis,F.H.F.; Harkins,J.D.; Tobin,T.. |
With the aim of determining the possible toxicity of amitraz after its prolonged use in horses, six English Thoroughbred horses received intravenous injections of amitraz (0.05, 0.10 or 0.15 mg/kg) weekly for four months, constituting the experimental group. Eight other animals (control group), via the same route following the same drug administration schedule and period of time, received the vehicle, dimethylformamide. At the end of this period, blood was collected from all the animals, and a comparison was made of the means of the values obtained for the various blood analyses: complete hemogram, alkaline phosphatase, gamma-glutamyltransferase, blood urea nitrogen, lactate dehydrogenase, aspartate aminotransferase, creatine phosphokinase, glucose,... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Horse; English Thoroughbred; Amitraz; Toxicity; Blood characteristics; Electrolytes. |
Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352002000400003 |
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Villalobos,Virginia; Bonilla,Ernesto; Castellano,Alan; Novo,Ernesto; Caspersen,Ralph; Giraldoth,Debora; Medina-Leendertz,Shirley. |
The effect of manganese toxicity on the ultrastructure of the olfactory bulb was evaluated. Male albino mice were injected intraperitoneally with MnCl2 (5 mg/Kg/day) five days per week during nine weeks. The control group received NaCl (0.9%). The olfactory bulbs of five mice from each group were processed for transmission electron microscopy after 2, 4, 6 and 9 weeks of manganese treatment. On week 2, some disorganization of the myelin sheaths was observed. After 4 weeks, degenerated neurons with dilated cisternae of rough endoplasmic reticulum and swollen mitochondria appeared. A certain degree of gliosis with a predominance of astrocytes with swollen mitochondria, disorganization of the endomembrane system, dilation of the perinuclear cisternae and... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Metal toxicity; Toxicity; Neurodegeneration; Electron microscopy. |
Ano: 2009 |
URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452009000300007 |
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Marcano,Letty; Carruyo,Ingrid; Fernández,Yusmary; Montiel,Xiomara; Torrealba,Zaida. |
The vanadium is a metal that presents great interest from the toxicological point of view, because of the numerous alterations that can take place in different biological systems. This work evaluated the capacity of vanadium accumulation and its correlation with genotoxic effects in root cells of Allium cepa L. The bulbs were cultivated in renovated filtered water each 24 h, at a temperature of 25 ± 0.5 ° C, in darkness and constant aeration. Treatments were carried out under the same experimental conditions, using water solutions of vanadium of 25, 50, 75 and 100 µ g/g for 0, 12, 24, 48 and 72 h. A control was carried out where metal solution was substituted by distilled water. After the treatment, the meristems were fixed with alcohol - acetic acid (3:1)... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Root cells; Vanadium; Toxicity; Accumulation; GFAAS. |
Ano: 2006 |
URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452006000200001 |
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AGUIAR,ALINE S DE; BOAVENTURA,GILSON T; ABRAHÃO,RAFAEL F; FREITAS,THATIANA L; TAKIYA,CHRISTINA M; FILHO,PORPHIRIO J S; SILVA,VILMA A DA. |
The aim of the present study was to evaluate the chronic toxicity of ethanol low blood levels in malnourished rats. Female Wistar rats (220 g) were subjected to either an ad libitum diet (W, well-nourished, n=10) or food restriction (M, malnourished, n=10). Water (WW and MW) or ethanol solution (W5% and M5%) was offered to half of each nutritional group (n=5) as the only fluid source. The treatment was continued for two months. After sacrifice, blood biochemical parameters and macroscopic, histologic and morphometric evaluation of the liver were performed. Results indicated that: Ethanol consumption was higher in malnourished rats and minimized body weight loss in malnourished rats, while it decreased the body weight gain in well-nourished ones. Behavioral... |
Tipo: Journal article |
Palavras-chave: Ethanol; Low dose; Malnutrition; Toxicity. |
Ano: 2009 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602009000100004 |
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Registros recuperados: 225 | |
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