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Characterization of the Brazilian endemic clone of methicillin-resistant Staphylococcus aureus (MRSA) from hospitals throughout Brazil 55
Oliveira,Geraldo A.; Faria,Juarez B.; Levyand,Carlos E.; Mamizuka,Elsa M..
The objective of this study was to characterize patterns of the Brazilian endemic clone of methicillin-resistant Staphylococcus aureus (MRSA) from hospitals throughout Brazil. We studied 83 MRSA strains isolated from patients hospitalized in 27 public and private hospitals in 19 cities located in 14 Brazilian states from September, 1995, to June, 1997. The MRSA strains were typed using antibiograms, bacteriophage typing and pulsed field gel electrophoresis (PFGE). The analysis of genomic DNA by PFGE showed that 65 isolates presented the same PFGE pattern. This pattern was present in all of the hospitals studied indicating the presence of an endemic MRSA clone widely disseminated throughout Brazilian hospitals (BEC). All isolates belonging to the BEC proved...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Staphylococus aureus; MRSA; Epidemiology; Brazilian endemic clone.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702001000400001
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Distribution of serotypes and evaluation of antimicrobial susceptibility among human and bovine Streptococcus agalactiae strains isolated in Brazil between 1980 and 2006 55
Pinto,Tatiana Castro Abreu; Costa,Natália Silva; Souza,Aline Rosa Vianna; Silva,Ligia Guedes da; Corrêa,Ana Beatriz de Almeida; Fernandes,Flavio Gimenis; Oliveira,Ivi Cristina Menezes; Mattos,Marcos Corrêa de; Rosado,Alexandre Soares; Benchetrit,Leslie Claude.
Streptococcus agalactiae is a common agent of clinical and subclinical bovine mastitis and an important cause of human infections, mainly among pregnant women, neonates and nonpregnant adults with underlying diseases. The present study describes the genetic and phenotypic diversity among 392 S. agalactiae human and bovine strains isolated between 1980 and 2006 in Brazil. The most prevalent serotypes were Ia, II, III and V and all the strains were susceptible to penicillin, vancomycin and levofloxacin. Resistance to clindamycin, chloramphenicol, erythromycin, rifampicin and tetracycline was observed. Among the erythromycin resistant strains, mefA/E, ermA and, mainly, ermB gene were detected, and a shift of prevalence from the macrolide resistance phenotype...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Streptococcus agalactiae; Pulsed field gel electrophoresis; Epidemiology; Serotyping; Resistance profile.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000200003
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Uncommon non-oncogenic HPV genotypes, TP53 and MDM2 genes polymorphisms in HIV-infected women in Southern Brazil 55
Entiauspe,Ludmila Gonçalves; Seixas,Fabiana Kömmling; Nunes,Emily Montosa; Rodrigues,Fernanda Martins; Dellagostin,Odir A.; Collares,Tiago; Silveira,Mariângela Freitas da.
Background:It is believed that Human Papillomavirus (HPV) and Human Immunodeficiency Virus coinfection contributes to increase the risk for cervical intraepithelial injuries. Several factors may contribute to cervical cancer (CC) development, including genetic variants such as TP53and MDM2 gene polymorphisms.Materials and methods:A hundred HIV-infected women were examined for HPV detection and its genotypes, as well as the frequencies of the SNPs Arg72Pro and SNP309 and their associations with CC risk factors. Nested Polymerase Chain Reaction (nPCR) was used for HPV detection and PCR-RFLP for TP53 and MDM2 SNP309 genotyping.Results:HPV DNA was detected in 68% of samples. A higher frequency of low-risk HPV genotypes (66.7%) was observed when compared to...
Tipo: Info:eu-repo/semantics/article Palavras-chave: HPV infection; HIV infection; Cervical cancer; Epidemiology.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000600643
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Seroprevalence of human cysticercosis in Jataí, Goiás state, Brazil 55
Guarda,Kaliny Xavier da; Costa-Cruz,Julia Maria; Barcelos,Ivanildes Solange da Costa.
ABSTRACT The Taenia solium cysticercosis affects millions of people worldwide and is considered a public health problem, especially in developing countries. The diagnosis of neurocysticercosis is complex and involves the analysis of epidemiological, clinical, neuroimaging, and immunological host data. Neurocysticercosis is endemic in Brazil, and is related to the cause of death mainly in the Southeast, South, and Central-West regions. The objective of this study was to determine the seroprevalence of cysticercosis in inhabitants of the city of Jataí, Goiás, in the Central-West region of Brazil from April to August 2012. A total of 529 serum samples were analyzed by enzyme-linked immunosorbent assay for detecting IgG antibodies against T. solium larvae, and...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Cysticercosis; Taenia solium; Epidemiology; Diagnosis; Brazil.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000200146
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Clinical and bacteriological characteristics of invasive pneumococcal disease after pneumococcal 10-valent conjugate vaccine implementation in Salvador, Brazil 55
Leite,Carolina Regis; Azevedo,Jailton; Galvão,Vivian Santos; Moreno-Carvalho,Otávio; Reis,Joice Neves; Nascimento-Carvalho,Cristiana.
Abstract Invasive pneumococcal disease is a relevant public health problem in Brazil, especially among children and the elderly. In July/2010 a 10-valent pneumococcal conjugate vaccine was introduced to the immunization schedule of Brazilian children under two years of age. Between July/2010 and December/2013 we conducted a case-series study on invasive pneumococcal disease in Salvador, Brazil to describe the clinical and bacteriological profile of invasive pneumococcal disease cases during the post-implementation period. Eighty-two cases were eligible. Mean age was 31 years (interquartile range, 3–42); 17.1% and 30.5% were under 2 years and 5 years, respectively. Pneumococcal meningitis (n = 64, 78.1%), bacteraemic pneumococcal pneumonia (n = 12, 14.6%)...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Streptococcus pneumoniae; Vaccine; Epidemiology.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000100056
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Chlamydia trachomatis and human papillomavirus coinfection: association with p16INK4a and Ki67 expression in biopsies of patients with pre-neoplastic and neoplastic lesions 55
Calil,Luciane Noal; Igansi,Cristine Nascente; Meurer,Luise; Edelweiss,Maria Isabel Albano; Bozzetti,Mary Clarisse.
The objective of this study was to identify the frequency of coinfection by human papillomavirus (HPV) and Chlamydia trachomatis (CT) in cervical lesions and relate it with immunohistochemical expression of p16INK4a and Ki67, both oncogenicity markers. A cross-sectional study with 86 women from primary care units in southern Brazil was conducted. Cervical swabs were collected for HPV-DNA and CT-DNA detection, through the polymerase chain reaction technique (PCR). The immunohistochemical analysis was performed on biopsy cervical tissue material to identify the expression of p16INK4a and Ki67 cell cycle markers. About 83 % were positive for HPV-DNA and 19% had coinfection with CT-DNA. Among coinfected women, 56% expressed p16INK4a. There was a statistically...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Epidemiology; Human papillomavirus 16; Biomarkers; Pharmacological.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000200006
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Is community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) an emerging pathogen among children in Brazil? 55
Paternina-de la Ossa,Rolando; Prado,Seila Israel do; Cervi,Maria Célia; Lima,Denissani Aparecida Ferrari dos Santos; Martinez,Roberto; Bellissimo-Rodrigues,Fernando.
ABSTRACT Background: Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is spreading worldwide, but little is known about the epidemiology of this pathogen in Brazil. Objective: To evaluate clinical and microbiological features of children with S. aureus infections admitted to a university hospital. Methods: This was a cross-sectional study evaluating the potential risk factors for CA-MRSA, and a retrospective cohort evaluating in-hospital clinical outcomes. To include patients with both community and hospital-associated infections, we screened the results of the microbiological laboratory tests from January 1, 2012, to December 31, 2016. According to the phenotype, we classified the isolates in Methicillin-Susceptible S. aureus...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Staphylococcus aureus; CA-MRSA; Epidemiology; Clinical features; Children; Susceptibility profile.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000500371
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Epidemiological profile of leishmaniasis at a reference service in the state of Alagoas, Brazil, from january 2000 to september 2008 55
Nunes,Willian da Silva; Araújo,Sócrates Rios; Calheiros,Cláudia Maria Lins.
Leishmaniasis is a parasitic disease found in the continents of Europe, Asia, Africa and the Americas. In Brazil, the disease is an important public health problem, occurring in most states, but mainly in the Northeast region of the country, with the state of Alagoas having a significant number of confirmed cases. The present study establishes and discusses the epidemiological profile of cases of leishmaniases treated at the Reference Center of Alagoas, Hospital Escola Hélvio de Farias Auto, between January 2000 and October 2008. During thisperiod, records of 2,104 patients notified to the hospital Epidemiological Surveillance Center were reviewed. The epidemiology of leishmaniasis, both visceral and tegumentary, has shown a profile that has changed over...
Tipo: Info:eu-repo/semantics/article Palavras-chave: American tegumentary leishmaniasis; Visceral leishmaniasis; Epidemiology.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000400005
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The prevalence of enteropathy due to Strongyloidiasis in Puerto Maldonado (Peruvian Amazon) 55
Egido,J. M.; De Diego,J. A.; Penin,P..
Human strongyloidiasis is an important health problem in the southeast region of Peruvian Amazon, due to its prevalence and long term morbidity. An epidemiological study was conducted in the Peruvian Amazon area of Puerto Maldonado to determine the prevalence of strongyloidiasis in the population. Stool samples were collected from 1,133 patients at the outpatient department of our clinic. Strongyloidiasis affected 221 examined patients (20%). Prevalence was highest in males, mostly in children and elderly men. People living in urban and marginal urban areas, those coming from outside the region, and Andean people, showed the highest prevalences. Pre-school children were more likely to be parasitized than older children. The most common symptoms were...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Strongyloides stercoralis; Epidemiology; Enteropathy; Peruvian Amazon.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702001000300003
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How are HCV-infected patients being identified in Brazil: a multicenter study 55
Portari-Filho,Luiz H.; Álvares-da-Silva,Mario R.; Gonzalez,Aline; Ferreira,Adalgisa P.; Nogueira,Cristiane V.; Mendes-Correa,Maria C.; Lima,José M.; Lopes,Edmundo P.; Brandão,Carlos E.; Ivantes,Cláudia; Lyra,André; Lindenberg,Andreia; Ferraz,Maria L..
ABSTRACT Background: Hepatitis C is an important health problem. In Brazil, 1-2 million people are infected. Despite this expressive number, and the availability of very successful treatment, many patients remained undiagnosed mainly because of the asymptomatic nature of the infection. Objectives: To describe epidemiological characteristics of HCV-infected patients seen at referral centers in Brazil, the source of referral, and the time spanned to reach a reference center, in order to improve the identification of undiagnosed patients. Methods: Multicenter observational, cross-sectional study carried out in 15 centers of Brazil, between January/2016 and June/2017. Data of patients with a confirmed diagnosis (anti-HCV and HCV-RNA) were collected by...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Epidemiology; Hepatitis C; HCV; Brazil.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702019000100034
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Assessment of family and neighbors of an individual infected with Wuchereria bancrofti from a non-endemic area in the city of Maceió, Brazil 55
Leite,Anderson B; Lima,Ana RV de; Leite,Renata B; Santos,Rafael V; Gonçalves,Johnathan EL; Rocha,Eliana MM; Fontes,Gilberto.
The family and neighbors of a patient infected with W. bancrofti microfilariae were assessed aiming to evaluate the occurrence of cases of lymphatic filariasis in a non-endemic area in the city of Maceió, in the Brazilian state of Alagoas. The patient had previously lived in an endemic focus; however, he has been living in an area where the parasite has never been detected for the past ten years. Female ingurgitated Culex quinquefasciatus mosquitoes captured in the houses of the microfilaremic individual and of his neighbors in the non-endemic region were also examined by polymerase chain reaction (PCR) technique. The thick blood smear examination, blood membrane filtration, and rapid immunochromatography (antigen search) revealed no infected individuals...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Wuchereria bancrofti; Lymphatic filariasis; Epidemiology; Culex.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000200002
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Epidemiology of Clostridium difficile: a hospital-based descriptive study in Argentina and Mexico 55
Lopardo,Gustavo; Morfin-Otero,Rayo; Moran-Vazquez,Iliana Isabel; Noriega,Fernando; Zambrano,Betzana; Luxemburger,Christine; Foglia,Ginamarie; Rivas,Enrique Eduardo.
A prospective study was conducted in four tertiary hospitals in Argentina and Mexico in order to describe the occurrence of Clostridium difficileinfection (CDI) in these settings. The objective was to evaluate the incidence of CDI in at-risk populations in Argentina (one center) and Mexico (three centers) and to further explore potential study sites for vaccine development in this region. A prospective, descriptive, CDI surveillance study was conducted among hospitalized patients aged ≥40 years who had received ≥48 h of antibiotic treatment. Stool samples were collected from those with diarrhea within 30 days after starting antibiotics and analyzed for toxins A and B by ELISA, and positive samples were further tested by toxinogenic culture and restriction...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Clostridium infections; Epidemiology; Latin America; Incidence.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000100008
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Western blot seroindeterminate individuals for Human T-lymphotropic Virus 1/2 (HTLV-1/2) in Fortaleza (Brazil): a serological and molecular diagnostic and epidemiological approach 55
Santos,Terezinha de Jesus Teixeira; Costa,Carlos Maurício de Castro; Goubau,Patrick; Vandamme,Anne-Mieke; Desmyter,Jan; Van Dooren,Sonia; Mota,Rosa M. S.; Costa,Francine Bovy de Castro; Oliveira,Ana C. S.; Gomes,Vânia Barreto A.F.; Carneiro-Proietti,Anna B.; Bruin,Veralice Meireles Sales de; Sousa,Francisca C. F. de; Oriá,Reinaldo Barreto.
How to handle Western blot (WB) seroindeterminate individuals for Human T-lymphotropic Virus 1/2 (HTLV-1/2) constitutes a challenge for blood banks and fam ilies. We made a cross-sectional study of 191 enzyme linked immunoassay (EIA) reactive individuals from the hematological center (HEMOCE) of Fortaleza (Brazil), examining their serological (WB) and molecular (PCR) diagnosis, and demographic profiles, as well as a possible association of their condition with other infectious pathologies and risk factors. Ethical institutional approval and personal consent were obtained. Out of 191 EIA reactive individuals, 118 were WB seroindeterminate and 73 were seropositive for HTLV-1/2. In the PCR analysis of 41 WB seroindeterminate individuals, 9 (22%) were positive...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Epidemiology; PCR; HTLV-1/2; Seroindeterminate individuals; Hepatitis; Syphilis; Blood transfusion.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000300005
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Epidemiological and clinical characteristics of cutaneous leishmaniasis and their relationship with the laboratory data, south of Brazil 55
Curti,Maura Cristiani de Moura; Silveira,Thaís Gomes Verzignassi; Arraes,Sandra Mara Alessi Aristides; Bertolini,Dennis Armando; Zanzarini,Paulo Donizeti; Venazzi,Eneide Aparecida Sabaini; Fernandes,Andrea Cláudia Silva; Teixeira,Jorge Juarez Vieira; Lonardoni,Maria Valdrinez Campana.
OBJECTIVE: To evaluate clinical, epidemiological and laboratorial aspects for the understanding of the disease characteristics and its relationship with diagnostic tests. METHODS: A retrospective, descriptive and analytical study involving 2,660 American cutaneous leishmaniasis (ACL) suspected patients from southern Brazil was undertaken between April 1986 and December 2005. Data on population characteristics and laboratory tests were obtained. Diagnostic laboratory tests used were direct search for Leishmania spp. (DS), Montenegro skin test (MST) and indirect immunofluorescent assay (IFA). RESULTS: 62.3% of patients were positive for at least one laboratory test. DS test was positive in 65.1%; MST in 92.3% and IFA in 70.0%. Although Cohen's Kappa test did...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Clinical laboratory techniques; Disease transmission; Infectious; Cutaneous leishmaniasis; Epidemiology.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000100003
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An overview of a diagnostic and epidemiologic reappraisal of cutaneous leishmaniasis in Iran 55
Farahmand,Mahin; Nahrevanian,Hossein; Shirazi,Hasti Atashi; Naeimi,Sabah; Farzanehnejad,Zahra.
Cutaneous leishmaniasis (CL) is a widespread tropical infection which has a high incidence rate in Iran. Leishmania tropica, the causative agent of anthroponotic cutaneous leishmaniasis (ACL), and Leishmania major, which causes zoonotic cutaneous leishmaniasis (ZCL), are endemic in various parts of Iran with a high incidence rate. The aim of this study was to evaluate the reappraisal of the diagnosis and epidemiology of CL in Iran, by different clinical, parasitological and molecular assays among patients suspected of CL referred to the Department of Parasitology, at the Pasteur Institute of Iran during 2006-2009. Two hundred samples from patients with ulcerative skin lesions were collected, clinical analyses were applied, data questionnaire was completed...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Parasitological analysis; Molecular biology; Leishmaniasis; Cutaneous; Iran; Epidemiology.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000100004
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Hepatitis E virus seroprevalence among schistosomiasis patients in Northeastern Brazil 55
Passos-Castilho,Ana Maria; de Sena,Anne; Domingues,Ana Lucia Coutinho; Lopes-Neto,Edmundo Pessoa; Medeiros,Tibério Batista; Granato,Celso Francisco Hernandez; Ferraz,Maria Lúcia.
Abstract Background Hepatitis E virus (HEV) can cause chronic infection with rapid progression to liver cirrhosis in immunocompromised patients. HEV seroprevalence in patients with Schistosoma mansoni in Brazil is unknown. We evaluated the prevalence of past or present HEV infection in schistosomiasis patients in Recife, Pernambuco, Brazil. A total of 80 patients with Schistosoma mansoni were consecutively enrolled in a cross-sectional study. Serum samples were tested for the presence of anti-HEV IgG antibodies by enzyme immunoassay (Wantai anti-HEV IgG, Beijing, China) and for the presence of HEV RNA using real time reverse transcriptase-polymerase chain reaction with primers targeting the HEV ORF2 and ORF3. Clinical and laboratory tests as well as...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Brazil; Epidemiology; Hepatitis E virus; Schistosomiasis; Seroprevalence.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000300007
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Seroprevalence of hepatitis B and C in the Western Brazilian Amazon region (Rio Branco, Acre): a pilot study carried out during a hepatitis B vaccination program 55
Tavares-Neto,J.; Almeida,D.; Soares,M. C.; Uchoa,R.; Viana,S.; Darub,R.; Farias,E.; Rocha,G.; Vitvitski,L.; Paraná,R..
In 1999, on the occasion of the application of the first vaccine dose during the state vaccination campaign against hepatitis B virus (HBV), 390 individuals from the town of Rio Branco, Acre, aged two or more years were selected for the determination of the seroprevalence of HBV and HCV. HBV markers (HBsAg, anti-HBs, and anti-HBc IgG) were determined on this occasion and anti-HBs antibodies were also assessed 30 days after the third vaccine dose. At the time of vaccination, 39% of the individuals were still susceptible to HBV, while 61% presented serologic evidence of previous HBV contact or previous vaccination. The individuals with previous HBV contact were significantly older (p<0.001) than those without HBV markers. Of the 192 individuals who...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hepatitis B vaccination; Amazonia; Hepatitis B; Hepatitis C; Epidemiology.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702004000200003
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Comparison of clinical and laboratory characteristics between children and adults with dengue 55
Souza,Luiz José de; Pessanha,Laís Bastos; Mansur,Laura Carvalho; Souza,Luiza Assed de; Ribeiro,Mariana Barbosa Tâmega; Silveira,Monique do Vale da; Souto Filho,João Tadeu Damian.
Over the past several years, the epidemiological profile of dengue has been changing progressively and is currently characterized by an increase in the number of cases in children under 15 years of age. This study was aimed at comparing the clinical and laboratory features between adults and children with dengue; therefore, we performed a cross-sectional analysis of 5686 individuals with laboratory-confirmed dengue who sought treatment at a healthcare facility in Rio de Janeiro, Brazil from 2010 to 2011. A multivariate analysis indicated that myalgia (OR = 2.58; CI 95% = 2.08-3.18), retro-orbital pain (OR = 1.36; CI 95% = 1.15-1.62), nausea (OR = 1.92; CI 95% = 1.60-2.30), and arthralgia (OR = 3.64; CI 95% = 2.72-4.89) were the most frequent clinical...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Dengue; Dengue fever; Clinical spectra; Epidemiology.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000100005
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Parainfluenza virus infections in a tropical city: clinical and epidemiological aspects 55
Fé,Mariana Mota Moura; Monteiro,André Jalles; Moura,Fernanda Edna Araújo.
Little information on the epidemiology and clinical characteristics of human parainfluenza virus (HPIV) infections, especially in children from tropical countries, has been published. The aim of this study was to determine the frequency of HPIV infections in children attended at a large hospital in Fortaleza in Northeast Brazil, and describe seasonal patterns, clinical and epidemiological characteristics of these infections. From January 2001 to December 2006, a total of 3070 nasopharyngeal aspirates collected from children were screened by indirect immunofluorescence for human parainfluenza viruses 1, 2, and 3 (HPIV-1, 2 and 3) and other respiratory viruses. Viral antigens were identified in 933 samples and HPIV in 117. The frequency of HPIV-3, HPIV-1 and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acute respiratory infections; Parainfluenza virus; Epidemiology; Brazil.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000300006
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The epidemiology of sepsis in a Brazilian teaching hospital 55
Kauss,IAM; Grion,Cintia MC; Cardoso,LTQ; Anami,EHT; Nunes,LB; Ferreira,GL; Matsuo,T; Bonametti,AM.
OBJECTIVES: The objective of this study was to estimate disease incidence and mortality rate of sepsis in a tertiary public hospital. METHODS: Patients admitted to the Intensive Care Unit (ICU) in 2004 and 2005 were monitored for sepsis using an observational longitudinal study design. Patients were monitored daily for diagnostic criteria of sepsis, according to ACCP/SCCM Consensus Conference criteria, until either death or hospital discharge. RESULTS: During the study, we analyzed 1,179 patients. Systemic Inflammatory Response Syndrome (SIRS) was present in 1,048 (88.9%) patients on admission, and was associated with infection in 554 (47.0%) patients. Of these, sepsis was diagnosed in 30 (2.5%) patients, while severe sepsis was diagnosed in 269 (22.8%)...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Sepsis; Incidence; Mortality; Epidemiology.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000300011
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