SABIIA - Sistema Aberto e Integrado de Informação em Agricultura (Sabiia)

Melo,Valdinaldo Aragão de; Melo,Gustavo Barreto de; Silva,Renata Lemos; Piva,Nestor; Almeida,Maria Luiza Dória.

Tuberculosis of the cystic duct lymph node associated with cholelithiasis is rare. We report a case of a 40 year-old woman with this pathology. She presented with anorexia, biliary colic, postprandial fullness and fever. Imaging studies revealed cholelithiasis and several visible portal lymph nodes. Cholecystectomy was performed and histopathological examination showed tuberculosis of the cystic duct lymph node without affecting the gallbladder. The presence of gallstones and lymphadenopathy in computed tomography, associated with persistent fever and symptoms that resemble cholecystitis, should cause suspicion of tuberculosis. However, diagnosis is usually achieved by microscopic appearance of caseating granulomas and isolation of Mycobacterium...

Severe low back pain due to retroperitoneal abscess formation in diabetic patients

Palavras-chave: Cystic duct; Lymph node; Tuberculosis; Gallstone.

Ano: 2004

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702004000100009

Ohmori,Masami; Kobayashi,Eiji; Harada,Kazuhiro; Sugimoto,Koh-ichi; Ohkami,Hitoshi; Tsutsumi,Haruhiko; Fujimura,Akio.

We report two cases of diabetic patients with severe low back pain associated with retroperitoneal abscesses. In the first case, multiple retroperitoneal and spinal epidural abscesses were detected. Paraplegia due to the spinal epidural abscess was not relieved by drainage of the abscess and subsequent antibiotic therapy. In the second case, drainage of the retroperitoneal abscess and antibiotics were immediately started, resulting in successful recovery. Thus, we suggest that if a diabetic patient complains of low back pain, potential abscess formations should be considered and given appropriate treatment before administering epidural anesthetic injections for pain relief.

Scalp folliculitis with Demodex: innocent observer or pathogen?

Palavras-chave: Low back pain; Retroperitoneal abscess; Paraplegia; Diabetes mellitus.

Ano: 2002

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000600007

Fernandez-Flores,Angel; Alija,Antonio.

Tipo: Info:eu-repo/semantics/other

Ano: 2009

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000200001

Evaluation of phenotypic tests to detect carbapenem-resistant Enterobacteriaceae in colonized patients hospitalized in intensive care units

Perez,Leandro Reus Rodrigues; Rodrigues,Diógenes; Dias,Cícero Gomes.

In this study, we aimed to evaluate the performance of different phenotypic tests to detect carbapenem-resistant Enterobacteriaceae. Three different phenotypic methods were evaluated: (1) combined-disk test of meropenem plus phenylboronic acid or EDTA reading after 24 h and 48 h; (2) selective/chromogenic read after 24 h and after 48 h; and (3) overnight selective enrichment broth containing 10 µg ertapenem disk followed by culture on MacConkey agar. A positive result in at least one of the methods was submitted to PCR for blaNDM-1, blaOXA-48, blaKPC, blaSPM-1, blaIMP, and blaGES detection. Carbapenem-resistant Enterobacteriaceae was detected in 31 (30.4%) of 102 rectal swabs evaluated. All isolates showed to be KPC-2-producing organisms. Results showed...

Tipo: Info:eu-repo/semantics/other

Palavras-chave: Carbapenems; Enterobacteriaceae; KPC; Surveillance.

Ano: 2015

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000400436

Fulminant pancytopenia due to cytomegalovirus infection in an immunocompetent adult

Koukoulaki,Maria; Ifanti,Georgia; Grispou,Eirini; Papastamopoulos,Vassilios; Chroni,Georgia; Diamantopoulos,Emmanouil; Skoutelis,Athanasios.

A case of severe and irreversible pancytopenia secondary to acute primary cytomegalovirus infection in an immunocompetent woman is described. The patient presented with thrombocytopenia, lymphopenia, anemia, and abnormal liver function tests. Treatment with corticosteroids and intravenous immunoglobulin was ineffective in reconstituting hemopoiesis. The patient developed severe sepsis and eventually expired.

Detection of mycobacteria in the bloodstream of patients with Acquired Immunodeficiency Syndrome in a University Hospital in Brazil

Palavras-chave: Cytomegalovirus; Pancytopenia; Immunocompetent; Fulminant; Irreversible.

Ano: 2010

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000200012

Oplustil,Carmen Paz; Leite,Olavo H.M.; Oliveira,Marilia S.; Sinto,Sumiko I.; Uip,David E.; Boulos,Marcos; Mendes,Caio F..

This study was done to determine the occurrence of mycobacteria in the bloodstreams of patients with fever and advanced AIDS in a Brazilian hospital. We also verified the capability of an automated method for recovering these bacteria. During a period of 19 months, 254 patients with AIDS were evaluated. Blood cultures were generally submitted in pairs and drawn separately. Blood cultures were processed by the BACTEC 460TB System (Becton Dickinson Microbiology Systems, Sparks, MD), using the Bactec 13A media (Becton Dickinson Microbiology Systems, Sparks, MD). Of the 530 vials submitted, 77 (14.5%) from 41 (16%) patients were positive. Mycobacterium avium complex was recovered from 45 (58.4%) of the 77 positive vials, corresponding to 22 (53.6%) patients...

Bilateral afrenal nodules due to histoplasmosis in an elderly

Palavras-chave: Mycobacterial infection; HIV; Automated diagnosis; AIDS.

Ano: 2001

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702001000500003

Carvalho,Flávio Pedreira de Freitas de; Curiati,José Antônio Esper; Mauad,Thaís; Incerti,Milena Mendes; Jacob Filho,Wilson.

We report a case history of an 84-year-old elderly male patient that presented with a clinical picture suggestive of adrenal failure and bilateral adrenal nodules detected by abdominal computed tomography. A fine needle-guided biopsy was inconclusive for achieving a final diagnosis. The patient died due to septic shock and the autopsy disclosed histoplasmosis with extensive bilateral necrosis of the adrenal glands. Although the adrenal involvement in chronic disseminated histoplasmosis has been described, there have been few reports of the infection being associated with adrenal insufficiency.

Differentiation of wild-type varicella-zoster strains from India and the Oka vaccine strain using a VZV open reading frame - 62 based PCR-RFLP technique

Palavras-chave: Histoplasmosis; Adrenal nodule; Addison disease; Elderly; Histoplasma capsulatum.

Ano: 2007

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000100033

Kaushik,Karishma S.; Lahiri,Kunal K.; Kapila,Ketoki; Kumar,Satish; Gupta,Rajiv M.; Karade,Santosh.

Since the introduction of varicella vaccination in India, surveillance of circulating VZV strains has gained significance. Differentiating wild-type VZV strains from the Oka vaccine strain can be achieved only by molecular genotyping methods. The development of PCR methods for VZV strain differentiation has been hampered by the fact that the VZV genome is highly conserved. We used VZV ORF 62 PCR-RFLP analysis to identify and differentiate wild-type VZV strains in India from the Oka vaccine strain. Digestion of VZV ORF 62 amplicons with SmaI, enabled accurate strain differentiation; the Oka strain was positive for three SmaI sites, compared to two SmaI sites in the wild-type VZV strains that we tested.

Antimicrobial susceptibility of Gram-negative bacteria in Brazilian hospitals: the MYSTIC Program Brazil 2003

Palavras-chave: Varicella-zoster virus; ORF 62; OKA strain.

Ano: 2008

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000400011

Kiffer,Carlos; Hsiung,Andre; Oplustil,Carmen; Sampaio,Jorge; Sakagami,Elsa; Turner,Philip; Mendes,Caio.

Establish the susceptibility pattern of Gram-negative bacteria causing infections in ICU patients, MYSTIC Program Brazil 2003. Gram-negative bacteria (n = 1,550) causing nosocomial infections were collected at 20 Brazilian centers. The central laboratory confirmed the identification and performed the susceptibility tests by Etest methodology (AB Biodisk, Solna, Sweden) for meropenem, imipenem, ciprofloxacin, ceftazidime, cefepime, cefotaxime, piperacillin/tazobactam, gentamicin, and tobramycin. Interpretation criteria used were according to National Committee for Clinical Laboratory Standards (NCCLS). Pseudomonas aeruginosa (30.3%) was the most frequent isolate, followed by E. coli (18.6%), Klebsiella pneumoniae (16.9%), Acitenobacter baumannii (8.8%), and...

Transfusion risk for hepatitis B, hepatitis C and HIV in the state of Santa Catarina, Brazil, 1991-2001

Palavras-chave: Drug resistance; Bacterial; Microbial sensitivity tests; Infection control; Carbapenems.

Ano: 2005

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702005000300004

Kupek,Emil.

We examined the time trend of residual risk of transfusing blood contaminated with HIV, hepatitis B and hepatitis C, in the largest blood bank of the state of Santa Catarina, Brazil, 1991-2001. The HIV risk was reduced approximately 10 times during the decade of 1990, to 1:48777, but then increased significantly by the end of 2001. A similar time trend was observed for hepatitis B and hepatitis C, although the increase was not significant in this case. Even during the period of lowest risk, the estimates were considerably higher than in developed countries.

Anti-glomerular basement membrane glomerulonephritis in an HIV positive patient: case report

Palavras-chave: Blood transfusion; HIV; Hepatitis B; Hepatitis C.

Ano: 2004

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702004000300007

Monteiro,Eduardo José Bellotto; Caron,Daiane; Balda,Carlos Alberto; Franco,Marcello; Pereira,Aparecido Bernardo; Kirsztajn,Gianna Mastroianni.

We report on a case of a patient with HIV infection, diagnosed 18 months prior to the development of an anti-glomerular basement membrane (anti-GBM) rapidly progressive glomerulonephritis; this is probably the first report of such an association. A 30-year-old white man presented with elevation of serum creatinine (1.3 - 13.5 mg/dL within one month). At admission, the urinalysis showed proteinuria of 7.2 g/L and 8,000,000 erythrocytes/mL. Renal biopsy corresponded to a crescentic diffuse proliferative glomerulonephritis mediated by anti-GBM, and serum testing for anti-GBM antibodies was positive; antinuclear antibodies (ANA) and anti-neutrophilic cytoplasmic antibodies (ANCA) were also positive. The patient underwent hemodyalisis and was treated with...

Two cases of pulmonary and pleural sparganosis confirmed by tissue biopsy and immunoserology

Palavras-chave: Anti-GBM glomerulonephritis; HIV; Urinary abnormalities.

Ano: 2006

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000100011

Chung,Sang Wan; Kim,Yee Hyung; Lee,Eun Jung; Kim,Dae Hyun; Kim,Gou Young.

Sparganosis in humans is an incidental infection and is known to be associated with eating insufficiently cooked meat of frogs and snakes or drinking unboiled stream water. Although it can involve various internal organs, pulmonary and pleural involvement due to sparganum is rare. Because we recently experienced two cases involving lung parenchyma and pleura that were misdiagnosed as bacterial pneumonia and lung cancer, we herein intend to present them in detail.

Avidity of IgG for rubella: an evaluation of the need for implementation at the Materno-Infantil Presidente Vargas Hospital in Porto Alegre, Rio Grande do Sul, Brazil

Palavras-chave: Sparganosis; Multiple pulmonary nodules; Parasites; Pleural effusion.

Ano: 2012

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000200018

Reis,M.M.; Tessaro,M.M.; Cruz e Silva,J.; Giordano,S. A.; d'Azevedo,P.A..

Rubella serum assays performed in the laboratory of the Materno-Infantil Presidente Vargas Hospital (HMIPV) from 1998 to 2002 were reviewed to determine if IgG avidity assays should be implemented. IgG was determined using the Enzyme Linked Fluorescent Assay, ELFA, VIDAS® system, bioMérieux or the Microparticle Enzyme Immunoassay, MEIA, Axsym® system, Abbott, and IgM was determined using the ELFA, VIDAS® system, bioMérieux, a capture format assay. Specific IgG was assayed in 2,863 samples, with positive results for 84% of the patients, for the most part with high levels of antibodies. IgM was assayed in 2,851 samples, being positive in 14 (0.49%) and inconclusive in 25 (0.88%). Serology for toxoplasmosis was also positive or inconclusive in 5 patients....

The effects of nitric oxide on the immune response during giardiasis

Palavras-chave: Rubella virus infection; Congenital infection; Avidity of IgG for rubella; Serology for rubella virus.

Ano: 2004

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702004000300009

Pavanelli,Wander Rogério; Gutierrez,Fredy Roberto Salazar; Silva,Jean Jerley Nogueira da; Costa,Ivete Conchon; Menezes,Maria Claudia Noronha Dutra de; Oliveira,Francisco José de Abreu; Itano,Eiko Nakagawa; Watanabe,Maria Angélica Ehara.

Nitric oxide (NO) is a free radical synthesized from L-arginine by different isoforms NO-synthases. NO possesses multiple and complex biological functions. NO is an important mediator of homeostasis, and changes in its generation or actions can contribute or not to pathological states. The knowledge of effects of NO has been not only important to our understanding of immune response, but also to new tools for research and treatment of various diseases. Knowing the importance of NO as inflammatory mediator in diverse infectious diseases, we decided to develop a revision that shows the participation/effect of this mediator in immune response induced against Giardia spp. Several studies already demonstrated the participation of NO with microbicidal and...

Biofilms: microbes and disease

Palavras-chave: Nitric oxide; Immune system; Giardiasis.

Ano: 2010

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000600010

Aparna,Madhu Sharma; Yadav,Sarita.

Bacteria that attach to surface aggregate in a hydrated polymeric matrix of their own synthesis to form biofilms. These represent microbial societies with their own defense and communication system. Transitioning from acute to chronic infection is frequently associated with biofilm formation.Bacteria in biofilms are innately more resistant to antimicrobial agents. The presence of indwelling medical devices increases the risk for biofilm formation and subsequent infection. The current antibiotic therapies are of limited effectiveness in resolving biofilms infection.This review attempts to discuss the stages in biofilm formation, their pathogenic mechanisms, effect of antimicrobial agents, detection and eradication of the biofilms.

Virus C genotype predisposes to primary hypothyroidism during interferon-α treatment for chronic hepatitis C

Palavras-chave: Biofilms; Staphylococci; Pseudomonas; Candida.

Ano: 2008

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000600016

Pavan,Maria Helena Postal; Pavin,Elizabeth João; Gonçales Jr,Fernando Lopes; Zantut-Wittmann,Denise Engelbrecht.

OBJECTIVE: The treatment of the chronic hepatitis C (HCV) with α-interferon is associated with thyroid dysfunction (TD). The aim of this study was to evaluate thyroid function outcome among patients with chronic HCV under treatment with conventional interferon (IFN) or peguilated interferon (PEG-IFN) in association with ribavirin. PATIENTS AND METHODS: We studied 293 patients with chronic HCV, submitted to drug therapy for 24 or 48 weeks. Initially, we evaluated FT4, TSH, TPOAb, TgAb, and continued to monitor FT4 and TSH every three months during therapy and six months thereafter. RESULTS: At baseline, TD prevalence was 6.82% (n = 20); 6.14% hypothyroidism; 0.68% hyperthyroidism. TPOAb was present in 5.46% of euthyroid patients. Out of 273 euthyroid...

Clinical and epidemiological features of patients with chronic hepatitis C co-infected with HIV

Palavras-chave: Hypothyroidism hepatitis C; Chronic interferon-α.

Ano: 2011

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000500006

Eduardo Lorens,Braga; André Castro,Lyra; Fabrizio,Ney-Oliveira; Lourianne,Nascimento; Adriano,Silva; Carlos,Brites; Rosicreuza,Marbak; Luiz Guilherme Costa,Lyra; Manuel L.,Ribeiro Neto; Koonj Asvin,Shah.

Co-infection with hepatitis C virus (HCV) and human immunodeficiency virus (HIV) is increasingly common and affects the clinical course of chronic hepatitis C. Highly active antiretroviral therapy has improved the life expectancy of HIV infected patients, but, by extending survival, it permits the development of HCV cirrhosis. This study tried to evaluate clinical and epidemiological features of patients with chronic hepatitis C co-infected with HIV. We evaluated 134 HCV-infected patients: i) group A - 65 co-infected HCV/HIV patients, ii) group B - 69 mono-infected HCV patients. The impact of HIV infection on HCV liver disease was analyzed using Child's score, ultrasound findings and liver histology. Patients were subjected to HCV genotyping and anti-HBs...

Prevalence of persistent proteinuria in stable HIV/AIDS patients and its association with HIV nephropathy

Palavras-chave: Hepatitis C; HIV; Co-infection; Clinical course; HCV genotype.

Ano: 2006

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000100004

Cavalcante,Maria Alina Gomes de Mattos; Coelho,Sandra Neiva; Lacerda,Heloísa Ramos.

Human immunodeficiency virus (HIV)-related glomerular disease is a cause of end-stage renal disease, though there is no recent data from Brazil concerning this syndrome. Persistent proteinuria (PPt) is the main marker for glomerular disease, especially levels above 1.5 g. We examined the prevalence of and associated risk factors for PPt, along with the prevalence of HIV-associated nephropathy (HIVAN) among AIDS patients. We interviewed 411 patients who were attended at the HIV/AIDS section of the Clinical Hospital of the Federal University of Pernambuco (Brazil) from January through June 2004. PPt was defined as a positive urine dipstick exam on at least two occasions. The analyzed risk factors were: black race, a low CD4 lymphocyte count (<200...

HLA-B*5701 frequency in Chilean HIV-infected patients and in general population

Palavras-chave: Proteinuria; HIV nephropathy; AIDS.

Ano: 2007

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000500003

Case of recurrent Paracoccidioidomycosis: 25 years after initial treatment

Poggi,Helena; Vera,Alejandra; Lagos,Marcela; Solari,Sandra; Rodríguez P,Luis; Pérez,Carlos M.

It has been demonstrated that HLA-B*5701 screening reduces the risk for hypersensitivity reaction to abacavir in HIV-infected patients. Since B*5701 prevalence varies among different populations, it is important to determine the carrier frequency prior to its use for the screening of HIV-infected patients.The aim of this study was to determine HLA-B*5701 carrier frequency in Chilean general population and HIV-infected patients referred for B*5701 typing. For that purpose 300 blood bank donors and 492 abacavir-naïve HIV-infected patients from Chile were screened for B*5701 by a sequence specific primer PCR.We detected 14/300 (4.7%) B*57-positive individuals in the Chilean general population, 11 (3.7%) were B*5701 positive, and 3 (1%) had another subtype.All...

Tipo: Info:eu-repo/semantics/other

Palavras-chave: HLA-B*5701; HIV; Abacavir; Chile; Pharmacogenetics.

Ano: 2010

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000500015

Araújo,Stanley de Almeida; Prado,Laura de Godoy Rousseff; Veloso,Juliana Marcia Ribeiro; Pedroso,Enio Roberto Pietra.