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Meningococcal disease before and after the introduction of meningococcal serogroup C conjugate vaccine. Federal District, Brazil BJID
Tauil,Márcia de Cantuária; Carvalho,Cleidiane Santos Rodrigues de; Vieira,Ataiza César; Waldman,Eliseu Alves.
OBJECTIVES: To analyze the behavior of meningococcal disease in the Federal District, Brazil, from 2005 to 2011, and to assess the direct impact of the meningococcal serogroup C conjugate vaccine. METHODS: A descriptive study of cases of meningococcal disease among residents of the Federal District. We included in the study confirmed cases of meningococcal disease reported to the local surveillance. To reduce underreporting we compared data to the Brazilian Mortality Database and the Public Health Laboratory Database. We studied sociodemographic, clinical, and pathogen-related variables. For the assessment of the impact of meningococcal serogroup C conjugate vaccine, which was introduced in 2010 for children under two years of age, we compared the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Meningococcal disease; Epidemiology; Control.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000400379
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Tuberculosis in Brazil: last ten years analysis - 2001-2010 BJID
Oliveira,Gisele Pinto de; Torrens,Ana Wieczorek; Bartholomay,Patrícia; Barreira,Draurio.
OBJECTIVE: To describe tuberculosis epidemiological situation in Brazil, as well as program performance indicators in 2001-2010 period, and discuss the relationship between changes observed and control measures implemented in this century first decade. METHODS: It is a descriptive study, data source was the Information System for Notifiable Diseases (Sinan), Mortality Information System (SIM), Unified Health System Hospital Information System (SIH/SUS) and TB Multidrug-resistant Surveillance System (MDR-TB/SS). Indicators analyzed were organized into four major groups: TB control program (TCP) coverage and case detection; morbidity; treatment and TCP performance; and mortality. RESULTS: In the years analyzed there was a decrease in the number of new cases...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Tuberculosis; Epidemiology; Surveillance; Information system; Data quality.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000200016
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Infection with human papillomaviruses of sexual partners of women having cervical intraepithelial neoplasia BJMBR
Rombaldi,R.L.; Serafini,E.P.; Villa,L.L.; Vanni,A.C.; Baréa,F.; Frassini,R.; Xavier,M.; Paesi,S..
Epidemiological studies show that human papillomaviruses (HPV) are strongly related to cervical cancer and cervical intraepithelial neoplasias (CIN). Unlike the case for women, there are no consistent data on the natural history of HPV in the male population even though these viruses are prevalent in males. We carried out a prospective study to assess the prevalence of HPV in males as well as the factors that determine such infections in 99 male sexual partners of women with CIN. The genitalia of the males were physically examined and subjected to peniscopy for the collection of scrapings which were subjected to the polymerase chain reaction and restriction fragment length polymorphism to detect HPV. Of the 99 males sampled, 54 (54.5%) were positive for...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cervical intraepithelial neoplasia; Epidemiology; Human papillomaviruses; Polymerase chain reaction.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000200003
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Trachoma among the Yanomami Indians BJMBR
Paula,J.S.; Medina,N.H.; Cruz,A.A.V..
The Yanomami are one of the last primitive groups of Indians living in Brazil. They have almost no contact with other cultures. The epidemiology of eye disease among Yanomami is virtually unknown. For the first time, a trachoma survey was conducted among Yanomami Indians in the State of Amazonas near the Venezuelan border of the Brazilian rain forest. Ophthalmic examination was carried out on a total of 613 individuals (338 males and 275 females) from eight Yanomami villages along the Marauiá River located in the upper Rio Negro Basin. Age was classified into three categories (children, adults, and elderly) and trachoma was classified into five grades: follicular, inflammatory intense, cicatricial, trichiasis, and corneal opacity. Trachoma was endemic in...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Trachoma; Yanomami; Epidemiology.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002001000007
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Molecular detection of Leishmania spp in Lutzomyia longipalpis in the city of Lavras, Minas Gerais, Brazil BJMBR
Castro,J.C.; Bueno,L.L.; Milagres,T.F.; Rêgo,F.D.; Gontijo,C.M.F.; Peconick,A.P.; Andrade,A.J.; Barçante,T.A.; Barçante,J.M.P..
Leishmaniasis is a neglected disease that affects a large part of the world population. Knowing the sand fly fauna of a region is of fundamental importance for guiding health surveillance actions related to the prevention and control of leishmaniasis. A total of 86 specimens of sand flies (60 females and 26 males) were collected. Using the classification proposed by Galati (2003), the following species were identified: Lutzomyia longipalpis (Lutz & Neiva, 1912), Migonemyia migonei (França, 1920), Evandromyia cortelezzi (Brethes, 1923), Ev. sallesi (Galvão & Coutinho, 1939), Nyssomyia whitmani (Atunes & Coutinho, 1939), Psathyromyia lutziana (Costa Lima, 1932), Ev. lenti (Mangabeira, 1938), Brumptomyia sp. (França and Parrot, 1921), and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Leishmaniasis; Sand fly; Epidemiology.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000900603
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Temperature, air pollution, and mortality from myocardial infarction in São Paulo, Brazil BJMBR
Sharovsky,R.; César,L.A.M.; Ramires,J.A.F..
An increase in daily mortality from myocardial infarction has been observed in association with meteorological factors and air pollution in several cities in the world, mainly in the northern hemisphere. The objective of the present study was to analyze the independent effects of environmental variables on daily counts of death from myocardial infarction in a subtropical region in South America. We used the robust Poisson regression to investigate associations between weather (temperature, humidity and barometric pressure), air pollution (sulfur dioxide, carbon monoxide, and inhalable particulate), and the daily death counts attributed to myocardial infarction in the city of São Paulo in Brazil, where 12,007 fatal events were observed from 1996 to 1998....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Epidemiology; Myocardial infarction; Mortality; Temperature; Atmospheric pressure; Air pollution.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004001100009
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Sleep habits and complaints of adults in the city of São Paulo, Brazil, in 1987 and 1995 BJMBR
Pires,M.L.N.; Benedito-Silva,A.A.; Mello,M.T.; Del Giglio,S.; Pompeia,C.; Tufik,S..
This study compares the prevalence of complaints of insomnia, excessive diurnal sleepiness, parasomnias, and sleep habits of the adult population in the city of São Paulo, Brazil, estimated in surveys carried out in 1987 and 1995. Representative samples of 1000 adult residents per survey were interviewed using a validated structured sleep questionnaire, the "UNIFESP Sleep Questionnaire". Difficulty maintaining sleep, difficulty initiating sleep and early morning awakening, occurring at least three times a week, were reported in 1987 and 1995, by 15.8/27.6, 13.9/19.1, and 10.6/14.2% of the interviewees, respectively, significantly increasing throughout time. These sleep problems were more often found among women. Frequencies of excessive diurnal sleepiness...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Sleep; Sleep disorders; Insomnia; Diurnal sleepiness; Parasomnias; Epidemiology; Sleep habits.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007001100011
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Reproducibility of carotid ultrasound measurements in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) at baseline BJMBR
Santos-Neto,P.J.; Sena-Santos,E.H.; Meireles,D.P.; Santos,I.S.; Bensenor,I.M.; Lotufo,P.A..
Carotid artery assessment by ultrasound is a non-invasive evaluation of subclinical atherosclerosis and a predictor of cardiovascular events. However, ultrasound examinations are operator-dependent. In the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil), ultrasound images have been acquired from more than 10,000 participants. In this article, we describe the reproducibility of carotid intima-media thickness (CIMT), carotid plaque detection, and carotid plaque score (defined as the number of arterial sites with plaques) using ELSA-Brasil protocol, in a subset of 118 participants. Two board-certified radiologists and a trained technician read carotid images. We calculated intra- and inter-observer intraclass correlation (ICC) for CIMT values. We...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Plaque; Intima-media; Epidemiology; Ultrasound; Imaging.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000800610
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Implications of infectious diseases and the adrenal hypothesis for the etiology of childhood acute lymphoblastic leukemia BJMBR
Azevedo-Silva,F.; Camargo,B.de; Pombo-de-Oliveira,M.S..
Acute leukemia is the most frequent cancer in children. Recently, a new hypothesis was proposed for the pathogenesis of childhood acute lymphoblastic leukemia (ALL). The so-called "adrenal hypothesis" emphasized the role of endogenous cortisol in the etiology of B-cell precursor ALL. The incidence peak of ALL in children between 3 to 5 years of age has been well documented and is consistent with this view. The adrenal hypothesis proposes that the risk of childhood B-cell precursor ALL is reduced when early childhood infections induce qualitative and quantitative changes in the hypothalamus-pituitary-adrenal axis. It suggests that the increased plasma cortisol levels would be sufficient to eliminate all clonal leukemic cells originating during fetal life....
Tipo: Info:eu-repo/semantics/other Palavras-chave: Lymphoblastic leukemia; Childhood infections; Epidemiology; Kala-azar; Adrenal hypothesis.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000300001
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High sensitivity C-reactive protein distribution in the elderly: the Bambuí Cohort Study, Brazil BJMBR
Assunção,L.G.S.; Eloi-Santos,S.M.; Peixoto,S.V..
The measurement of the serum concentration of the acute-phase reactant C-reactive protein (CRP) provides a useful marker in clinical practice. However, the distribution of CRP is not available for all age and population groups. This study assessed the distribution of high sensitivity-CRP (hs-CRP) by gender and age in 1470 elderly individuals from a Brazilian community that participates in the Bambuí Cohort Study. Blood samples were collected after 12 h of fasting and serum samples were stored at -70°C. Measurements were made with a commercial hs-CRP immunonephelometric instrument. More than 50% of the results were above 3.0 mg/L for both genders. Mean hs-CRP was higher in women (3.62 ± 2.58 mg/L) than in men (3.03 ± 2.50 mg/L). This difference was observed...
Tipo: Info:eu-repo/semantics/article Palavras-chave: C-reactive protein; Elderly; Epidemiology; Cardiovascular risk; Brazil.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012001200025
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Why are the rates of cesarean section in Brazil higher in more developed cities than in less developed ones? BJMBR
Ribeiro,V.S.; Figueiredo,F.P.; Silva,A.A.M.; Bettiol,H.; Batista,R.F.L.; Coimbra,L.C.; Lamy,Z.C.; Barbieri,M.A..
The objective of the present study was to investigate factors associated with cesarean sections in two cities located in different regions of Brazil and to determine factors that explain the higher cesarean section rate in the more developed city, Ribeirão Preto, compared to the less developed one, São Luís. Data from two cohort studies comprising 2846 women in Ribeirão Preto in 1994, and 2443 women in São Luís in 1997/1998 were used. Adjusted and non-adjusted risk estimates were calculated using a Poisson regression model. The cesarean section rate was 33.7% in São Luís and 50.8% in Ribeirão Preto. Adjusted analysis in a joint sequential model revealed a 51% higher risk of cesarean section in Ribeirão Preto compared to São Luís (prevalence rate ratio...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cesarean section; Epidemiology; Obstetrics; Health services; Risk factors.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000900008
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Examining life-course influences on chronic disease: the importance of birth cohort studies from low- and middle- income countries. An overview BJMBR
Batty,G.D.; Alves,J.G.; Correia,J; Lawlor,D.A..
The objectives of this overview are to describe the past and potential contributions of birth cohorts to understanding chronic disease aetiology; advance a justification for the maintenance of birth cohorts from low- and middle-income countries (LMIC); provide an audit of birth cohorts from LMIC; and, finally, offer possible future directions for this sphere of research. While the contribution of birth cohorts from affluent societies to understanding disease aetiology has been considerable, we describe several reasons to anticipate why the results from such studies might not be directly applied to LMIC. More than any other developing country, Brazil has a tradition of establishing, maintaining and exploiting birth cohort studies. The clear need for a...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Birth cohort; Chronic disease; Developing country; Epidemiology; Life-course.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000900015
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Epidemiology of recurrent venous thrombosis BJMBR
Ribeiro,D.D.; Lijfering,W.M.; Barreto,S.M.; Rosendaal,F.R.; Rezende,S.M..
Venous thrombosis, including deep vein thrombosis and pulmonary embolism, is a common disease that frequently recurs. Recurrence can be prevented by anticoagulants, but this comes at the risk of bleeding. Therefore, assessment of the risk of recurrence is important to balance the risks and benefits of anticoagulant treatment. This review briefly outlines what is currently known about the epidemiology of recurrent venous thrombosis, and focuses in more detail on potential new risk factors for venous recurrence. The general implications of these findings in patient management are discussed.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Recurrent venous thrombosis; Epidemiology; Risk factors.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000100001
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Examining life-course influences on chronic disease: the Ribeirão Preto and São Luís birth cohort studies (Brazil) BJMBR
Batty,G.D.
More than any other low- and middle-income country, Brazil has the longest research tradition of establishing, maintaining and exploiting birth cohort studies. This research pedigree is highlighted in the present issue of the Brazilian Journal of Medical and Biological Research, which contains a series of twelve papers from the Ribeirão Preto and São Luis birth cohort studies from the Southeast and Northeast of Brazil, respectively. The topics covered in this raft of reports vary and include predictors of perinatal health and maternal risk factors, early life determinants of cardiovascular risk factors in childhood and adolescence, use of health services, and a description of dietary characteristics of young adults, amongst other topics. There is also a...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Birth cohort; Chronic disease; Developing country; Epidemiology; Life-course.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000900001
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Acute leukemias in Piauí: comparison with features observed in other regions of Brazil BJMBR
Rego,M.F.N.; Pinheiro,G.S.; Metze,K.; Lorand-Metze,I..
Differences in age and sex distribution as well as FAB (French-American-British classification) types have been reported for acute leukemias in several countries. We studied the demographics and response to treatment of patients with acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) between 1989 and 2000 in Teresina, Piauí, and compared these results with reports from Brazil and other countries. Complete data concerning 345 patients (230 ALL, 115 AML) were reviewed. AML occurred predominantly in adults (77%), with a median age of 34 years, similar to that found in the southeast of Brazil but lower than the median age in the United States and Europe (52 years). FAB distribution was similar in children and adults and FAB-M2 was the most...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acute lymphoblastic leukemia; Acute myeloid leukemia; Epidemiology.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000300007
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Overview of Zika virus (ZIKV) infection in regards to the Brazilian epidemic BJMBR
Slavov,S.N.; Otaguiri,K.K.; Kashima,S.; Covas,D.T..
Zika virus (ZIKV), a mosquito-borne flavivirus, belongs to the Flaviviridae family, genus Flavivirus. ZIKV was initially isolated in 1947 from a sentinel monkey in the Zika forest, Uganda. Little clinical importance was attributed to ZIKV, once only few symptomatic cases were reported in some African and Southeast Asiatic countries. This situation changed in 2007, when a large outbreak was registered on the Yap Island, Micronesia, caused by the Asian ZIKV lineage. Between 2013 and 2014, ZIKV spread explosively and caused many outbreaks in different islands of the Southern Pacific Ocean and in 2015 autochthonous transmission was reported in Brazil. Currently, Brazil is the country with the highest number of ZIKV-positive cases in Latin America. Moreover,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Zika virus; ZIKV; Transmission; Epidemiology; Congenital infection; Brazil.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000500201
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Epidemiological and functional implications of molecular variants of human papillomavirus BJMBR
Sichero,L.; Villa,L.L..
Human papillomavirus genomes are classified into molecular variants when they present more than 98% of similarity to the prototype sequence within the L1 gene. Comparative nucleotide sequence analyses of these viruses have elucidated some features of their phylogenetic relationship. In addition, human papillomavirus intratype variability has also been used as an important tool in epidemiological studies of viral transmission, persistence and progression to clinically relevant cervical lesions. Until the present, little has been published concerning the functional significance of molecular variants. It has been shown that nucleotide variability within the long control region leads to differences in the binding affinity of some cellular transcriptional...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Human papillomavirus; DNA sequencing; Oncogenic potential; Cervical cancer; Immunity; Epidemiology.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000600002
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Etiology of diarrheal infections in children of Porto Velho (Rondonia, Western Amazon region, Brazil) BJMBR
Orlandi,P.P.; Magalhães,G.F.; Matos,N.B.; Silva,T.; Penatti,M.; Nogueira,P.A.; Pereira da Silva,L.H..
In the present study, 470 children less than 72 months of age and presenting acute diarrhea were examined to identify associated enteropathogenic agents. Viruses were the pathogens most frequently found in stools of infants with diarrhea, including 111 cases of rotavirus (23.6% of the total diarrhea cases) and 30 cases of adenovirus (6.3%). The second group was diarrheogenic Escherichia coli (86 cases, 18.2%), followed by Salmonella sp (44 cases, 9.3%) and Shigella sp (24 cases, 5.1%). Using the PCR technique to differentiate the pathogenic categories of E. coli, it was possible to identify 29 cases (6.1%) of enteropathogenic E. coli (EPEC). Of these, 10 (2.1%) were typical EPEC and 19 (4.0%) atypical EPEC. In addition, there were 26 cases (5.5%) of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Diarrheal disease; Enteropathogens; Escherichia coli; Epidemiology; Western Amazon.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000400011
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Bone mineral density in Brazilian men 50 years and older BJMBR
Zerbini,C.A.F.; Latorre,M.R.O.; Jaime,P.C.; Tanaka,T.; Pippa,M.G.B..
Bone mineral density (BMD) in the lumbar spine (LSBMD), femoral neck (FNBMD) and whole body (WBBMD) and whole body tissue composition were evaluated in 288 Brazilian men 50 years and older, 80% white and 20% Mulattoes. Age was inversely correlated with WBBMD (r = -0.20) and FNBMD (r = -0.21) but not with LSBMD (r = 0.03). Body mass index and weight showed a strong positive correlation with WBBMD (r = 0.48 and 0.54), LSBMD (r = 0.37 and 0.45) and FNBMD (r = 0.42 and 0.48). Correlation with height was positive but weaker. No significant bone loss at the lumbar spine level was observed as the population aged. FNBMD and WBBMD decreased significantly only in the last decade (age 70-79) studied. BMD was higher for Brazilian men as compared to Brazilian women at...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bone mineral density; Osteoporosis; Epidemiology.
Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000001200005
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A pilot study on the identification of human papillomavirus genotypes in tongue cancer samples from a single institution in Ecuador BJMBR
Delgado Ramos,G.M.; Cotter,T.G.; Flor Ramos,L.; Torres Floril,V.; Ramos Martinez,G.A.; Ruiz-Cabezas,J.C..
The relationship between human papillomavirus (HPV) and oropharyngeal squamous cell carcinoma has been established. However, data from Ecuador is limited. The objective of this study was to characterize HPV infection in Ecuadorian patients with tongue cancer. Fifty-three patients with tongue cancer treated at the tertiary referral center Sociedad de Lucha Contra el Cancer (SOLCA), Guayaquil, between 2006 and 2011 were identified. Linear Array® HPV genotyping was used to identify the presence and types of HPV on formalin-fixed paraffin-embedded biopsy samples from these patients with tongue cancer. HPV was identified in 42% (n=22) and high-risk (HR) HPV in 17% (n=9), with 18 different HPV types identified. The most common types were the HR HPV 33 (14%) and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Human papillomavirus; Oropharyngeal; Oral; Ecuador; Head and neck cancer; Epidemiology.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018001100609
Registros recuperados: 316
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