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Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum BJID
Morais,Orlando Oliveira de; Porto,Cláudia; Coutinho,Anglya Samara Silva Leite; Reis,Carmélia Matos Santiago; Teixeira,Marcus de Melo; Gomes,Ciro Martins.
Aureobasidium pullulans is a causal agent of phaeohyphomycosis, occasionally found in men and animals. As an agent of different opportunistic fungal processes, it may cause fungemia, systemic infections and abscesses in different viscera. This paper aims to report a case of a patient with infection of the lymphatic system by A. pullulans. A 23-year-old patient being treated for erythema nodosum leprosum presented a 60-day complaint of daily fever, hoarseness, odynophagia and weight loss. Laboratory tests showed pancytopenia with severe neutropenia, cervical adenomegaly and solid contrast uptake lesion in the oropharyngeal region. Due to neutropenia and sepsis the patient was initially treated with cefepime and vancomycin, but there was no clinical...
Tipo: Info:eu-repo/semantics/report Palavras-chave: HIV; Pneumonia; Macrolides; Mortality.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000300019
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The effectiveness of a bundle in the prevention of ventilator-associated pneumonia BJID
Ferreira,Cléria Rodrigues; de Souza,Denis Fabiano; Cunha,Thulio Marques; Tavares,Marcelo; Reis,Samir Seme Arab; Pedroso,Reginaldo Santos; Röder,Denise Von Dolinger de Brito.
Abstract Objectives The aim of this study was to evaluate the impact of a bundle called FAST HUG in ventilator-associated pneumonia, weigh the healthcare costs of ventilator-associated pneumonia patients in the intensive care unit, and hospital mortality due to ventilator-associated pneumonia. Material and methods The study was performed in a private hospital that has an 8-bed intensive care unit. It was divided into two phases: before implementing FAST HUG, from August 2011 to August 2012 and after the implementation of FAST HUG, from September 2012 to December 2013. An individual form for each patient in the study was filled out by using information taken electronically from the hospital medical records. The following data was obtained from each...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Ventilator-associated pneumonia; Checklist; Cost; Mortality.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000300008
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Pediatric mortality due to nosocomial infection: a critical approach BJID
Lopes,Julia Marcia Maluf; Goulart,Eugenio Marcos Andrade; Starling,Carlos Ernesto Ferreira.
Nosocomial infection is a frequent event with potentially lethal consequences. We reviewed the literature on the predictive factors for mortality related to nosocomial infection in pediatric medicine. Electronic searches in English, Spanish and Portuguese of the PubMed/MEDLINE, LILACS and Cochrane Collaboration Databases was performed, focusing on studies that had been published from 1996 to 2006. The key words were: nosocomial infection and mortality and pediatrics/neonate/ newborn/child/infant/adolescent. The risk factors found to be associated with mortality were: nosocomial infection itself, leukemia, lymphopenia, neutropenia, corticosteroid therapy, multiple organ failure, previous antimicrobial therapy, catheter use duration, candidemia, cancer,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Nosocomial infection; Mortality; Prognosis; Healthcare quality; Pediatric hospital.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000500013
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Hyponatremia, acute kidney injury, and mortality in HIV-related toxoplasmic encephalitis BJID
Libório,Alexandre B.; Silva Jr,Geraldo B.; Silva,Carolina G.C.H.; Lima Filho,Francisco J.C.; Studart Neto,Adalberto; Okoba,Willy; Bruin,Veralice M.S. de; Araújo,Sônia M.H.A.; Daher,Elizabeth F..
BACKGROUND: There are no reports on hyponatremia and acute kidney injury (AKI) involved in the course of HIV-related toxoplasmic encephalitis (TE). The main objective of this study was to describe the occurrence of hyponatremia and its relationship with AKI and mortality in HIV-related toxoplasmic encephalitis (TE). METHODS: This was a retrospective cohort study on patients with HIV-related TE. AKI was considered only when the RIFLE (risk, injury, failure, loss, end-stage) criterion was met, after the patient was admitted. RESULTS: A total of 92 patients were included, with a mean age of 36 ± 9 years. Hyponatremia at admission was observed in 43 patients (46.7%), with AKI developing in 25 (27.1%) patients during their hospitalization. Sulfadiazine was the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Toxoplasmosis; Encephalitis; Hyponatremia; Acute kidney injury; HIV; Mortality.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000600010
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Staphylococcus aureus bacteremia: what is the impact of oxacillin resistance on mortality? BJID
Cassettari,V.C.; Strabelli,T.; Medeiros,E.A.S..
In order to analyse the impact of oxacillin resistance on the mortality of Staphylococcus aureus bacteremia, and to assess the antimicrobial susceptibility of community-acquired strains in two large university hospitals (the Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo and the Instituto Central do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo), we carried out a four-month-long prospective cohort study, which included 163 consecutive cases of S. aureus bacteremia. Of these, 140 (85.9%) were hospital-acquired, 9 (5.5%) were community-acquired and 14 (8.6%) were of indeterminate origin. No cases of community-acquired infection by oxacillin-resistant S. aureus was identified....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Staphylococcus aureus; Bacteremia; Mortality.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702005000100012
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Staphylococcus aureus bacteremia: comparison of two periods and a predictive model of mortality BJID
Conterno,Lucieni de Oliveira; Wey,Sérgio Barsanti; Castelo,Adauto.
Staphylococcus aureus is an important pathogen causing bacteremia, primarily affecting hospitalized patients. We studied the epidemiology of S. aureus bacteremia, comparing two periods (early and mid 1990s) and developed a predictive model of mortality. A nested case-control was done. All 251 patients over 14 years old with positive blood cultures for S. aureus were selected. MRSA (methicillin resistant S. aureus) was isolated in 63% of the cases. When comparing the two periods MRSA community-acquired bacteremia increased from 4% to 16% (p=0.01). There was no significant difference in the mortality rate between the two periods (39% and 33%, p=0.40). Intravascular catheters provoked 24% of the cases of bacteremia and were associated with the lowest rate of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Staphylococcus aureus; Bacteremia; Mortality.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000600004
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Strategies to reduce mortality and morbidity due to AIDS-related cryptococcal meningitis in Latin America BJID
Vidal,Jose E.; Oliveira,Augusto C. Penalva de; Dauar,Rafi F.; Boulware,David R..
Latin America is the region with the third most AIDS-related cryptococcal meningitis infections globally. Highly active antiretroviral therapy (HAART) has reduced the number of infections; however, the number of deaths and the case-fatality rate continues to be unacceptable. In this review, we focus on the burden of AIDS-related cryptococcosis in Latin America and discuss potential strategies to reduce early mortality from Cryptococcus. In this review, we highlight the importance of: (1) earlier HIV diagnosis and HAART initiation with retention-in-care to avoid AIDS; (2) pre-HAART cryptococcal antigen (CRAG) screening with preemptive fluconazole treatment; (3) better diagnostics (e.g. CRAG testing); and (4) optimal treatment with aggressive management of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cryptococcal meningitis; Cryptococccosis; Epidemiology; Diagnosis; Treatment; Mortality; Latin America.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000300008
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Predictors of 7- and 30-day mortality in pediatric intensive care unit patients with cancer and hematologic malignancy infected with Gram-negative bacteria BJID
Costa,Patrícia de Oliveira; Atta,Elias Hallack; Silva,André Ricardo Araujo da.
Background:Infection with Gram-negative bacteria is associated with increased morbidity and mortality. The aim of this study was to evaluate the predictors of 7- and 30-day mortality in pediatric patients in an intensive care unit with cancer and/or hematologic diseases and Gram-negative bacteria infection.Methods:Data were collected relating to all episodes of Gram-negative bacteria infection that occurred in a pediatric intensive care unit between January 2009 and December 2012, and these cases were divided into two groups: those who were deceased seven and 30 days after the date of a positive culture and those who survived the same time frames. Variables of interest included age, gender, presence of solid tumor or hematologic disease, cancer status,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cancer; Pediatric intensive care unit; Infection with Gram-negative bacteria; Mortality.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000600591
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Mortality rate after open Roux-in-Y gastric bypass: a 10-year follow-up BJMBR
Bruschi Kelles,S.M.; Diniz,M.F.H.S.; Machado,C.J.; Barreto,S.M..
The prevalence of obesity has increased to epidemic status worldwide. Thousands of morbidly obese individuals undergo bariatric surgery for sustained weight loss; however, mid- and long-term outcomes of this surgery are still uncertain. Our objective was to estimate the 10-year mortality rate, and determine risk factors associated with death in young morbidly obese adults who underwent bariatric surgery. All patients who underwent open Roux-in-Y gastric bypass surgery between 2001 and 2010, covered by an insurance company, were analyzed to determine possible associations between risk factors present at the time of surgery and deaths related and unrelated to the surgery. Among the 4344 patients included in the study, 79% were female with a median age of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Survival analysis; Mortality; Follow-up studies; Morbid obesity; Roux-in-Y gastric bypass; Surgeon expertise.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000700617
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Temperature, air pollution, and mortality from myocardial infarction in São Paulo, Brazil BJMBR
Sharovsky,R.; César,L.A.M.; Ramires,J.A.F..
An increase in daily mortality from myocardial infarction has been observed in association with meteorological factors and air pollution in several cities in the world, mainly in the northern hemisphere. The objective of the present study was to analyze the independent effects of environmental variables on daily counts of death from myocardial infarction in a subtropical region in South America. We used the robust Poisson regression to investigate associations between weather (temperature, humidity and barometric pressure), air pollution (sulfur dioxide, carbon monoxide, and inhalable particulate), and the daily death counts attributed to myocardial infarction in the city of São Paulo in Brazil, where 12,007 fatal events were observed from 1996 to 1998....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Epidemiology; Myocardial infarction; Mortality; Temperature; Atmospheric pressure; Air pollution.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004001100009
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Association between elevated adiponectin level and adverse outcomes in patients with heart failure: a systematic review and meta-analysis BJMBR
Bai,Wenwei; Huang,Jingjing; Zhu,Min; Liu,Xiaoyong; Tao,Jianping.
Studies regarding the prognostic value of circulating adiponectin level in patients with heart failure are conflicting. The aim of this meta-analysis was to evaluate the association between elevated circulating adiponectin level and adverse outcomes in patients with heart failure. We searched PubMed and Embase databases from their inception to June 2018. Original observational studies that investigated the prognostic value of adiponectin in heart failure patients and reported all-cause mortality or combined endpoints of death/readmission as outcome measure were included. Pooled risk ratio (RR) with 95% confidence intervals (CI) were estimated by higher versus lower circulating adiponectin level. A total of 7 studies involving 862 heart failure patients...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Adiponectin; Heart failure; Mortality; Readmission; Meta-analysis.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000700610
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C-reactive protein in acute coronary syndrome: association with 3-year outcomes BJMBR
Schaan,B.D.; Pellanda,L.C.; Maciel,P.T.; Duarte,E.R.; Portal,V.L..
Inflammatory markers have been associated with clinical outcome in patients with acute coronary syndrome (ACS). The present study evaluated the role of high-sensitivity C-reactive protein (CRP) measurements as a predictor of late cardiovascular outcomes after ACS. One hundred and ninety-nine ACS patients in a Coronary Care Unit from March to November 2002 were included and were reassessed clinically after ~3 years. Clinical variables and CRP levels were evaluated as predictors of major cardiovascular events (MACE, defined as the occurrence of cardiac death, ischemic stroke or myocardial infarction) and mortality. Statistical analyses included Cox multivariable analysis and survival curves (Kaplan-Meier). Of the 199 patients, 11 died within 1 month (5.5%)....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acute coronary syndromes; Inflammatory markers; C-reactive protein; Major cardiovascular events; Mortality.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009001200019
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Association of sulfur dioxide exposure with circulatory system deaths in a medium-sized city in Brazil BJMBR
Amancio,C.T.; Nascimento,L.F.C..
There is a demonstrable association between exposure to air pollutants and deaths due to cardiovascular diseases. The objective of this study was to estimate the effects of exposure to sulfur dioxide on mortality due to circulatory diseases in individuals 50 years of age or older residing in São José dos Campos, SP. This was a time-series ecological study for the years 2003 to 2007 using information on deaths due to circulatory disease obtained from Datasus reports. Data on daily levels of pollutants, particulate matter, sulfur dioxide (SO2), ozone, temperature, and humidity were obtained from the São Paulo State Environmental Agency. Moving average models for 2 to 7 days were calculated by Poisson regression using the R software. Exposure to SO2 was...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Air pollution; Sulfur dioxide; Cardiovascular diseases; Mortality; Air pollutants; Stroke.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012001100013
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Cyst infection in hospital-admitted autosomal dominant polycystic kidney disease patients is predominantly multifocal and associated with kidney and liver volume BJMBR
Balbo,B.E.P.; Sapienza,M.T.; Ono,C.R.; Jayanthi,S.K.; Dettoni,J.B.; Castro,I.; Onuchic,L.F..
Positron-emission tomography/computed tomography (PET/CT) has improved cyst infection (CI) management in autosomal dominant polycystic kidney disease (ADPKD). The determinants of kidney and/or liver involvement, however, remain uncertain. In this study, we evaluated clinical and imaging factors associated with CI in kidney (KCI) and liver (LCI) in ADPKD. A retrospective cohort study was performed in hospital-admitted ADPKD patients with suspected CI. Clinical, imaging and surgical data were analyzed. Features of infected cysts were evaluated by PET/CT. Total kidney (TKV) and liver (TLV) volumes were measured by CT-derived multiplanar reconstruction. CI was detected in 18 patients who experienced 24 episodes during an interval of 30 months (LCI in 12, KCI...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Autosomal dominant polycystic kidney disease; Cyst infection; Positron-emission tomography/computed tomography; Kidney volume; Liver volume; Mortality.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000700584
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Effects of prenatal exposure to a mild chronic variable stress on body weight, preweaning mortality and rat behavior BJMBR
Cabrera,R.J.; Rodríguez-Echandía,E.L.; Jatuff,A.S.G.; Fóscolo,M..
Early stimulation has been shown to produce long-lasting effects in many species. Prenatal exposure to some strong stressors may affect development of the nervous system leading to behavioral impairment in adult life. The purpose of the present work was to study the postnatal harmful effects of exposure to variable mild stresses in rats during pregnancy. Female Holtzman rats were submitted daily to one session of a chronic variable stress (CVS) during pregnancy (prenatal stress; PS group). Control pregnant rats (C group) were undisturbed. The pups of PS and C dams were weighed and separated into two groups 48 h after delivery. One group was maintained with their own dams (PS group, N = 70; C group, N = 36) while the other PS pups were cross-fostered with C...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Prenatal stress; Chronic stress; Body weight; Behavior; Mortality; Rat.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999001000009
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Application of a modified sequential organ failure assessment score to critically ill patients BJMBR
Ñamendys-Silva,S.A.; Silva-Medina,M.A.; Vásquez-Barahona,G.M.; Baltazar-Torres,J.A.; Rivero-Sigarroa,E.; Fonseca-Lazcano,J.A.; Domínguez-Cherit,G..
The purpose of the present study was to explore the usefulness of the Mexican sequential organ failure assessment (MEXSOFA) score for assessing the risk of mortality for critically ill patients in the ICU. A total of 232 consecutive patients admitted to an ICU were included in the study. The MEXSOFA was calculated using the original SOFA scoring system with two modifications: the PaO2/FiO2 ratio was replaced with the SpO2/FiO2 ratio, and the evaluation of neurologic dysfunction was excluded. The ICU mortality rate was 20.2%. Patients with an initial MEXSOFA score of 9 points or less calculated during the first 24 h after admission to the ICU had a mortality rate of 14.8%, while those with an initial MEXSOFA score of 10 points or more had a mortality rate...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Sequential organ failure assessment score; Organ dysfunction; Critically ill patients; Mortality; Intensive care unit survival; MEXSOFA.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000200186
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Elevated levels of plasma osteoprotegerin are associated with all-cause mortality risk and atherosclerosis in patients with stages 3 to 5 chronic kidney disease BJMBR
Nascimento,M.M.; Hayashi,S.Y.; Riella,M.C.; Lindholm,B..
Osteoprotegerin (OPG) regulates bone mass by inhibiting osteoclast differentiation and activation, and plays a role in vascular calcification. We evaluated the relationship between osteoprotegerin levels and inflammatory markers, atherosclerosis, and mortality in patients with stages 3-5 chronic kidney disease. A total of 145 subjects (median age 61 years, 61% men; 36 patients on hemodialysis, 55 patients on peritoneal dialysis, and 54 patients with stages 3-5 chronic kidney disease) were studied. Clinical characteristics, markers of mineral metabolism (including fibroblast growth factor-23 [FGF-23]) and inflammation (high-sensitivity C-reactive protein [hsCRP] and interleukin-6 [IL-6]), and the intima-media thickness (IMT) in the common carotid arteries...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Atherosclerosis; Chronic kidney disease; Inflammation; Mortality; Osteoprotegerin.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014001100995
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Acute kidney injury in AIDS: frequency, RIFLE classification and outcome BJMBR
Libório,A.B.; Mota,R.M.S.; Abreu,K.L.S.; Silva,A.E.B.; Araújo,S.M.H.A.; Daher,E.F..
The objective of the present study was to evaluate the characteristics of acute kidney injury (AKI) in AIDS patients and the value of RIFLE classification for predicting outcome. The study was conducted on AIDS patients admitted to an infectious diseases hospital inBrazil. The patients with AKI were classified according to the RIFLE classification: R (risk), I (injury), F (failure), L (loss), and E (end-stage renal disease). Univariate and multivariate analyses were used to evaluate the factors associated with AKI. A total of 532 patients with a mean age of 35 ± 8.5 years were included in this study. AKI was observed in 37% of the cases. Patients were classified as "R" (18%), "I" (7.7%) and "F" (11%). Independent risk factors for AKI were thrombocytopenia...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acute kidney injury; HIV; AIDS; Prognosis; Mortality; RIFLE.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010001100013
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Incidence, risk factors and prognostic factors of acute renal failure in patients admitted to an intensive care unit BJMBR
Mataloun,S.E.; Machado,F.R.; Senna,A.P.R.; Guimarães,H.P.; Amaral,J.L.G..
The objective of the present study was to assess the incidence, risk factors and outcome of patients who develop acute renal failure (ARF) in intensive care units. In this prospective observational study, 221 patients with a 48-h minimum stay, 18-year-old minimum age and absence of overt acute or chronic renal failure were included. Exclusion criteria were organ donors and renal transplantation patients. ARF was defined as a creatinine level above 1.5 mg/dL. Statistics were performed using Pearsons' chi2 test, Student t-test, and Wilcoxon test. Multivariate analysis was run using all variables with P < 0.1 in the univariate analysis. ARF developed in 19.0% of the patients, with 76.19% resulting in death. Main risk factors (univariate analysis) were:...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acute renal failure; Risk factors; Prognostic factors; Intensive care unit; Mortality.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006001000010
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The effect of performing corrections on reported uterine cancer mortality data in the city of São Paulo BJMBR
Antunes,J.L.F.; Wünsch-Filho,V..
Reports of uterine cancer deaths that do not specify the subsite of the tumor threaten the quality of the epidemiologic appraisal of corpus and cervix uteri cancer mortality. The present study assessed the impact of correcting the estimated corpus and cervix uteri cancer mortality in the city of São Paulo, Brazil. The epidemiologic assessment of death rates comprised the estimation of magnitudes, trends (1980-2003), and area-level distribution based on three strategies: i) using uncorrected death certificate information; ii) correcting estimates of corpus and cervix uteri mortality by fully reallocating unspecified deaths to either one of these categories, and iii) partially correcting specified estimates by maintaining as unspecified a fraction of deaths...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Uterine cancer; Cervical cancer; Mortality; Statistical models; Socioeconomic factors; São Paulo.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000800012
Registros recuperados: 306
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