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| Registros recuperados: 3.453 | |
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| Lazhar Mhadhbi; Jose Fumega; Moncef Boumaiza; Ricardo Beiras. |
| A new toxic menace, polybrominated diphenyl ethers (PBDEs), is being detected in the aquatic environment all over the world. The environmental presence of PBDEs and its entry into the environment as BDE-47 and -99 make quality aquatic toxicity data necessary to assess the aquatic hazard risk of PBDs. This study examines the effects of three PBDE-47 and -99 on embryo and larval stages of the marine flatfish turbot (_Psetta maxima_). The acute toxicity of the three PBDEs was examined and NOEC, LOEC, LC10 and LC50 were calculated. All tested compounds caused lethal as well as nonlethal malformations during embryo development. The effects of PBDEs in the different life stages of turbot were analysed. PBDEs seemed to be teratogenic at concentrations higher than... |
| Tipo: Manuscript |
Palavras-chave: Chemistry; Ecology; Earth & Environment. |
| Ano: 2010 |
URL: http://precedings.nature.com/documents/4656/version/2 |
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| Ekaterina Chernyaeva; Pavel Dobrynin; Natalia Pestova; Natalia Matveeva; Vladimir Zhemkov; Andrei Kozlov. |
| Molecular epidemiological features of Mycobacterium tuberculosis strains spread among different patient groups in Russia is not studied well. The aim of our study was to compare genotypes of M.tuberculosis strains circulating among TB patients from different groups: homeless, HIV-infected, prisoners and general population of St.Petersburg citizens. 
One hundred fifty M.tuberculosis complex isolates from different TB patient groups were studied using spoligotyping method. 
The majority of studied M.tuberculosis isolates in all groups belonged to Beijing family (56% among homeless; 77% among HIV-infected; 60% among general population; 83% among prisoners). There were no significant difference in Beijing family prevalence... |
| Tipo: Manuscript |
Palavras-chave: Genetics & Genomics; Microbiology. |
| Ano: 2011 |
URL: http://precedings.nature.com/documents/6073/version/2 |
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| Heather A. Piwowar; Wendy W. Chapman. |
| Repurposing research data holds many benefits for the advancement of biomedicine, yet is very difficult to measure and evaluate. We propose a data reuse registry to maintain links between primary research datasets and studies that reuse this data. Such a resource could help recognize investigators whose work is reused, illuminate aspects of reusability, and evaluate policies designed to encourage data sharing and reuse. |
| Tipo: Poster |
Palavras-chave: Bioinformatics. |
| Ano: 2008 |
URL: http://precedings.nature.com/documents/2152/version/1 |
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| Theodor Ackbarow; Markus J. Buehler. |
| Proteins constitute the elementary building blocks of a vast variety of biological materials such as cellular protein networks, spider silk or bone, where they create extremely robust, multi-functional materials by self-organization of structures over many length- and time scales, from nano to macro. Some of the structural features are commonly found in a many different tissues, that is, they are highly conserved. Examples of such universal building blocks include alpha-helices, beta-sheets or tropocollagen molecules. In contrast, other features are highly specific to tissue types, such as particular filament assemblies, beta-sheet nanocrystals in spider silk or tendon fascicles. These examples illustrate that the coexistence of universality and... |
| Tipo: Manuscript |
Palavras-chave: Biotechnology; Chemistry; Ecology; Molecular Cell Biology. |
| Ano: 2007 |
URL: http://precedings.nature.com/documents/826/version/1 |
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| Brahma Reddy Induri; Stephen DiFazio; Danielle Ellis; Gancho Slavov; Tong-Ming Yin; Gerald Tuskan. |
| Abstract ID#: 26642
Background and Methods:

Cadmium (Cd), ranked the 7th most hazardous substance, is one of the most widespread pollutants of soil and water in industrialized nations. Its increased movement in soil-plant systems is posing a serious threat to human health. Cd, without any known functions in plants, was found to be toxic even at minute concentrations, leading to the development of symptoms such as leaf roll, chlorosis and root and shoot growth reduction. Phytoremediation is an emerging cost-effective and environment friendly technology that utilizes high biomass producing plants including Populus plants to remove, transform or stabilize contaminants in soils. The objectives of our study... |
| Tipo: Presentation |
Palavras-chave: Genetics & Genomics; Plant Biology. |
| Ano: 2010 |
URL: http://precedings.nature.com/documents/5410/version/1 |
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| Rodrick Wallace. |
| The Stanley Miller experiment suggests that amino acid-based life is ubiquitous in our universe, although its varieties are not likely to have followed the particular, highly contingent and path-dependent, trajectory found on Earth. Are many of these life forms likely to be conscious in ways that we would recognize? Almost certainly. Will many conscious entities develop high order technology? Less likely. If so, will we be able to communicate with them? Only on a basic level, and only with profound difficulty. The argument is straightforward. |
| Tipo: Manuscript |
Palavras-chave: Neuroscience; Bioinformatics; Evolutionary Biology. |
| Ano: 2010 |
URL: http://precedings.nature.com/documents/5286/version/1 |
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| István Bókkon; Jack Tuszynski; Vahid Salari. |
| Previously, we have pointed out that biophoton production can be a controlled process that originates from regulated redox/radical reactions. Our biophoton experiments support the notion that various visual related phenomena such as discrete retinal noise, retinal phosphenes as well as negative afterimages are due to biophotons. We have also suggested a new model, stating that the brain is able to create biophysical pictures in retinotopic visual areas via redox regulated biophotons of synchronized neurons. According to our interpretation, visualization (imagery) is a special kind of representation i.e., visual imagery requires peculiar inherent biophysical processes. Our idea of biophysical visual virtual reality in retinotopic areas may be a possible... |
| Tipo: Poster |
Palavras-chave: Neuroscience. |
| Ano: 2011 |
URL: http://precedings.nature.com/documents/6051/version/1 |
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| I. C. Baianu. |
| There is an urgent need for the early detection of diseases such as Alzheimer’s (AD) and Cancers in order to enable their successful treatment. Cancer is the second major cause of death after Heart Disease, and AD is the third major cause of death with major, human and financial/economics trillion dollar consequences for the society. Nuclear Medicine is concerned with applications in Medicine of Nuclear Science and Engineering techniques and knowledge. Three major Nuclear Medicine techniques that are established for diagnostic and research purposes are: Positron Emission Tomography (PET) and CAT/CT, Nuclear Magnetic Resonance Imaging (NMRI/MRI). However, these three techniques have also major limitations in terms of either cost or image... |
| Tipo: Manuscript |
Palavras-chave: Biotechnology; Cancer; Chemistry; Genetics & Genomics; Molecular Cell Biology; Neuroscience; Pharmacology; Bioinformatics. |
| Ano: 2011 |
URL: http://precedings.nature.com/documents/6271/version/1 |
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| Lucas Wardil; Jafferson K. L. da Silva. |
| The emergence of cooperation has been widely studied in the context of game theory on structured populations. Usually the individuals adopt one strategy against all their neighbors. The structure can provide reproductive success for the cooperative strategy, at least for low values of defection tendency. Other mechanisms, such punishment, can also be responsible for cooperation emergence. But what happens if the players adopt simultaneously different strategies against each one of their opponents, not just a single one? Here we study this question in the prisoner dilemma scenario structured on a square lattice and on a ring. We show that if an update rule is defined in which the players replace the strategy that furnishes the smallest payoff, a... |
| Tipo: Manuscript |
Palavras-chave: Evolutionary Biology. |
| Ano: 2009 |
URL: http://precedings.nature.com/documents/3035/version/1 |
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| Bruce Rothschild; Donald Neiffer; Steve Marks. |
| Pachydermatoperiostosis, a rare form of hypertrophic osteoarthropathy, is of unknown etiology and previously thought limited to humans. The only periosteal reaction previously reported in prosimians is related to renal disease. Notation of hypertrophic osteoarthritis in three prosimians led to recognition that this was the first non-human documentation of the disease. Three related red ruffed lemurs (Varecia variegatus rubra) had diaphyseal periosteal reaction classic for hypertrophic osteoarthropathy. Workup was negative for known underlying causes and for the secondary hyperparathyroidism which produces bone alterations in black Eulemur macao, black and white Varecia variegatatus varigatus and ringtail Lemur catta lemurs. Recognition of facial coarsening... |
| Tipo: Manuscript |
Palavras-chave: Developmental Biology; Evolutionary Biology. |
| Ano: 2011 |
URL: http://precedings.nature.com/documents/6374/version/1 |
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| Patrick Gürtler; Esther Meissner; Ulrich Busch. |
| Import and planting of biotech crops is strictly regulated in Europe. In order to observe these strict regulations, an efficient surveillance of the European market is required. In Europe, data on authorised biotech crops from foreign countries are on hand, however, only scarce information on non-authorised biotech crops is available. Experience of the last years has shown that non-authorized biotech crops (e.g. biotech-papaya, Bt10-maize, LL601-rice and Bt63-rice) were detected on the European market. The Bavarian Health and Food Safety Authority is responsible for the detection of illegal imports and for labelling control of Food and Feed in Bavaria (Germany). The quantitative real-time PCR is the method of choice for the detection of genetic... |
| Tipo: Poster |
Palavras-chave: Biotechnology; Plant Biology. |
| Ano: 2010 |
URL: http://precedings.nature.com/documents/4444/version/1 |
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| Samiran Bisai; Kaushik Bose. |
| This paper deals with cross-sectional studies carried out during the period 2004-2007. It is based on eight data sets of tribals of Paschim Medinipur and Bankura Districts of West Bengal and Keonjhar District of Orissa. The tribes include Bhumijs, Kora Mudis, Lodhas, Santals, Bathudis and Savars. Height and weight were measured following standard techniques. The body mass index (BMI) was computed following standard equation. Nutritional status (chronic energy deficiency, CED) was evaluated using internationally accepted cut-off values of BMI. We followed the World Health Organization's classification (1995) of the public health problem of low BMI, based on adult populations worldwide. Our results show that, in general, among the tribes... |
| Tipo: Manuscript |
Palavras-chave: Developmental Biology; Ecology; Earth & Environment; Data Standards. |
| Ano: 2012 |
URL: http://precedings.nature.com/documents/7068/version/1 |
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| Dorian Aur. |
| The occurrence of seizures is a rare event with a very low probability of incidence. Therefore, a new paradigm is required to understand how epileptic seizures are generated. Specifically, analytical models and experimental data analysis show that the process underlying seizure generation is a severe dysfunctional regulation of neuronal activity inside the epileptogenic region. Translated into significant changes of endogenous electric field, this dysfunction acts at fundamental level of charge dynamics and leads to chaotic diffusion and electrical resonances within clustered regions with high frequency oscillations (HFO). Since the altered regulation can be modeled by perturbed Hamiltonian systems with many degrees of freedom that describe the motion of... |
| Tipo: Manuscript |
Palavras-chave: Neuroscience. |
| Ano: 2010 |
URL: http://precedings.nature.com/documents/5398/version/1 |
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| Jack R. Foucher; Daniel Gounot; Bich-Thuy Pham; Corinne Marrer; Andre Dufour. |
| MRI is generally thought to have no impact on cognition. Although safety experiments have shown that MRI is not harmful, its finer effects have not been investigated. Because we repeatedly observed delayed response time during functional MRI (fMRI), we designed an experiment to confirm this effect and to identify its causal factor(s), including environment, noise, static magnetic field and/or gradient switch. Here we show that the participants had increased response times of +70 ms (up to +30%) in two different detection tasks, with most of this effect due to the 2 Tesla static magnetic field. The latter also specifically accounted for the longer time interval needed to detect two stimuli as occurring successively rather than simultaneously. These... |
| Tipo: Manuscript |
Palavras-chave: Neuroscience. |
| Ano: 2008 |
URL: http://precedings.nature.com/documents/2443/version/1 |
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| Rohith Anand Varikoti; Rahul P. Gangwal; Gaurao V. Dhoke; Venkata Krishnan Ramaswamy; Abhay T. Sangamwar. |
| Tuberculosis is one of the leading contagious diseases, caused by Mycobacterium tuberculosis. Despite improvements in anti-tubercular agents, it remains one of the most prevalent infectious diseases worldwide, responsible for a total of 1.6 million deaths annually. The emergence of multidrug resistant strains highlighted the need of discovering novel drug targets for the development of anti-tubercular agents. 2-C-methyl-D-erythritol-4-phosphate cytidyltransferase (IspD) is an enzyme involved in MEP pathway for isoprenoid biosynthesis, which is considered an attractive target for the discovery of novel antibiotics for its essentiality in bacteria and absence in mammals. In the present study, we have employed structure based drug design approach to develop... |
| Tipo: Manuscript |
Palavras-chave: Chemistry. |
| Ano: 2012 |
URL: http://precedings.nature.com/documents/7088/version/1 |
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| Sandeep Swargam; K Mahesh; Amineni Umamaheswari. |
| Human myotrophin is the smallest ankyrin repeat protein implicated as a factor to induce cardiac hypertrophy. Activation of myotrophin was observed during acute myocardial infarction (MI). In acute coronary syndrome (ACS) patients, myotrophin acts as a self-governing predictor of major adverse cardiac events (MACE). Therefore, human myotrophin serves as an effective drug target for discovery of new potential drugs. Recent human myotropin inhibitors have poor pharmalogical properties leading to intolerable side effects. Hence, ligand based virtual screening protocol of CADD method was persuaded in the present study to propose new class potential myotrophin inhibitors. Docking was done by using Schrödinger software suite 2010 (maestro v9.1), docked... |
| Tipo: Poster |
Palavras-chave: Bioinformatics. |
| Ano: 2011 |
URL: http://precedings.nature.com/documents/6562/version/1 |
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| Joseph N. T. Darbah; Thomas D. Sharkey; David F. Karnosky. |
| High temperature, especially above 35oC, is known to reduce leaf photosynthetic rate in many tree species. This study investigated the effect of high temperature on isoprene-emitting (aspen) and non- emitting (birch) trees under ambient and elevated CO2 under open field conditions. Aspen trees tolerate heat better than birch trees and elevated CO2 protects both species against moderate heat stress. The increased thermotolerance in aspen trees compared to the birch trees may result from the aspen's ability to produce isoprene. Elevated CO2 increased carboxylation capacity, photosynthetic electron transport capacity and triose phosphate use in both birch and aspen trees. High temperature decreased all of these parameters in birch regardless of CO2... |
| Tipo: Manuscript |
Palavras-chave: Ecology; Earth & Environment. |
| Ano: 2008 |
URL: http://precedings.nature.com/documents/1533/version/1 |
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| Registros recuperados: 3.453 | |
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