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| Registros recuperados: 104 | |
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| Machado,Terezinha Feitosa; Pereira,Rita de Cássia Alves; Batista,Valéria Chaves Vasconcelos. |
| Lippia alba is a shrub of the Verbenaceae family, popularly known as lemon balm. It's essential oil is said to have broad-spectrum antimicrobial activity whose effectiveness varies according to its composition, which is influenced by both biotic and abiotic factors. The present study aimed to evaluate the antimicrobial effectiveness of oil taken from the leaves of L. alba collected at different times of the year, against microorganisms of importance in food. The oil, obtained by hydrodistillation, was tested against standard cultures of Pseudomonas aeruginosa, Salmonella choleraesuis, Escherichia coli, Staphylococcus aureus, Listeria monocytogenes and Listeria innocua using agar diffusion techniques. The different sampling times had a big influence on the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Lippia alba; Antimicrobial activity; Seasonality. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-66902014000300011 |
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| SILVA,Emily Marcele Soares; SILVA,Ingrid Reis da; OGUSKU,Mauricio Morishi; CARVALHO,Clarice Maia; MAKI,Cristina Sayuri; PROCÓPIO,Rudi Emerson de Lima. |
| ABSTRACT Tuberculosis (TB) remains one of the most deadly communicable infectious diseases, causing 1.4 million deaths in 2015 worldwide due to many conditions, including the inadequate treatment and the emergence of multidrug-resistant strains of the causal agent, Mycobacterium tuberculosis. Therefore, drugs developed from natural sources, as microorganisms and plant extracts, are a frequent target for the research and discovery of antimicrobial compounds. The current study started the characterization of compounds produced by an Aspergillus fumigatus isolated from copaíba (Copaifera multijuga) that efficiently inhibits M. tuberculosis by releasing the compounds into the fermentation broth under specific culture conditions. A preliminary assay was carried... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Mycobacterium spp.; Antimicrobial activity; Copaíba; Chromatography. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672018000100063 |
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| Corrêa, Paulo Roberto Ceridório; UEL; Pinto, Artur da Silveira; UFMG; Silva, Grácia Divina de Fátima; UFMG; Vieira Filho, Sidney Augusto; UFOP; Duarte, Lucienir Pains; UFMG; Yamada-Ogatta, Sueli Fumie; UEL. |
| The effect of 2-pyridinecarboxylic acid (picolinic acid) on trypanosomes of the subgenus Schizotrypanum isolated from the bat Phyllostomus hastatus was determined in this study. Picolinic acid, at 50 µg mL-1, inhibited epimastigote growth by 99% after 12 days incubation. In addition, trypomastigote motility decreased by 50% after 6h and completely after 24h in the presence of 50 µg mL-1 picolinic acid. The 50% cytotoxic concentration on HEp-2 cell line was 275 µg mL-1 after 4 days incubation. Altogether, these results indicate higher toxicity against trypanosomes. The inhibitory effect of picolinic acid on epimastigote growth can be partially reversed by nicotinic acid and L-tryptophan, suggesting a competitive inhibition.... |
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Palavras-chave: Ciências Biológicas; Microbiologia; 2.12.02.00-1 bat trypanosome; Schizotrypanum; 2-pyridinecarboxylic acid; Antimicrobial activity Atividade antimicrobiana bat trypanosome; Schizotrypanum; 2-pyridinecarboxylic acid; Antimicrobial activity. |
| Ano: 2011 |
URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/6482 |
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| Lund, Rafael Guerra; Universidade Federal de Pelotas; Serpa, Rosana; Universidade Federal de Pelotas; Nascente, Patrícia da Silva; Universidade Federal de Pelotas; Ribeiro, Gladis Aver; Universidade Federal de Pelotas; Freitag, Rogério Antonio; Universidade Federal de Pelotas; Del Pino, Francisco Augusto Burkert; Universidade Federal de Pelotas. |
| In vitro tests could be a valuable tool for the evaluation of medicinal plants’ antimicrobial activity. Mentha arvensis of the Lamiaceae family is one of the most frequently traditional plants used in Brazil. Hydroalcoholic extracts of M. arvensis were analyzed for antimicrobial activity on Streptococcus mutans, Streptococcus sobrinus and Candida albicans. Three different assays (agar diffusion, broth macro- and micro-dilution methods) were used to evaluate antimicrobial activity. Although hydroalcoholic extracts of M. arvensis did not show any antibacterial effect, its antifungal activity against C. albicans was revealed. According to the micro-dilution broth assay, MIC of the hydroalcoholic extract from leaves of M. arvensis on Candida albicans strains... |
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Palavras-chave: 2.12.00.00-9 Microbiologia Mentha arvensis; Antimicrobial activity; Streptococcus mutans; Candida albicans Microbiologia. |
| Ano: 2012 |
URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/8959 |
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| Azimi Mahalleh, Afsaneh; Sharayei, Parvin; Mortazavi, Seyed Ali; Azarpazhooh, Elham; Niazmand, Razieh. |
| Pulsed electric field (PEF) treatment was used for extracting effective components from Nepeta (Nepeta binaludensis Jamzad). A response surface method was used to investigate the effects of independent process variables (voltage of pulsed electric field (VPEF): 2, 4 and 6 KV/cm and number of pulsed electric field (NPEF): 20, 40 and 60 n) on the yield (Y) and antioxidant characteristics: total phenolic compounds (TPC), 1,1- diphenyl -2- picrylhydrazyl free radical scavenging (DPPHsc), ferric reducing-antioxidant power (FRAP), half maximal of radical-scavenging activity (IC50) of Nepeta extract (aerial parts). According to Derringer’s desired function approach, the optimal conditions based on both individual and combinations of all process variables were... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Phenolic compounds; Nepeta binaludensis; Response Surface Methodology; Pulsed electric field; Antimicrobial activity. |
| Ano: 2019 |
URL: http://www.cigrjournal.org/index.php/Ejounral/article/view/5391 |
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| Azimi Mahalleh, Afsaneh; Sharayei, Parvin; Mortazavi, Seyed Ali; Azarpazhooh, Elham; Niazmand, Razieh. |
| Pulsed electric field (PEF) treatment was used for extracting effective components from Nepeta (Nepeta binaludensis Jamzad). A response surface method was used to investigate the effects of independent process variables (voltage of pulsed electric field (VPEF): 2, 4 and 6 KV/cm and number of pulsed electric field (NPEF): 20, 40 and 60 n) on the yield (Y) and antioxidant characteristics: total phenolic compounds (TPC), 1,1- diphenyl -2- picrylhydrazyl free radical scavenging (DPPHsc), ferric reducing-antioxidant power (FRAP), half maximal of radical-scavenging activity (IC50) of Nepeta extract (aerial parts). According to Derringer’s desired function approach, the optimal conditions based on both individual and combinations of all process variables were... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Phenolic compounds; Nepeta binaludensis; Response Surface Methodology; Pulsed electric field; Antimicrobial activity. |
| Ano: 2019 |
URL: http://www.cigrjournal.org/index.php/Ejounral/article/view/5391 |
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| SIRAKANYAN,SAMVEL N.; GERONIKAKI,ATHINA; SPINELLI,DOMENICO; HAKOBYAN,ELMIRA K.; KARTSEV,VIKTOR G.; PETROU,ANTHI; HOVAKIMYAN,ANUSH A.. |
| ABSTRACT Annulated thienopyrimidine derivatives attracted big interest of the scientific community due to their broad spectrum of biological activities among which are the inhibition of phosphodiesterase, antiproliferative and antimicrobial activities. As a continuation of our studies on the synthesis and biological activity of fused thieno[3,2-d]pyrimidine derivatives, the goal of this paper is the synthesis and study of the properties of compounds containing different heterocycles such as fused thieno[2,3-b]pyridine and tetrazolo[1,5-c]pyrimidine in the same molecule. Thus, starting from the ethyl 1-amino-5-isopropyl-8,8-dimethyl-8,9-dihydro-6H-pyrano[4,3-d]thieno[2,3-b]pyridine-2-carboxylate 1, efficient methods for obtaining new... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Amino derivatives; Antimicrobial activity; Azide/tetrazole equilibrium; Nucleophilic substitution; Thieno[3; 2-d]pyrimidine. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000301043 |
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| ALPAY,MERVE; DULGER,GORKEM; SAHIN,IBRAHIM E.; DULGER,BASARAN. |
| Abstract: In this study, the antimicrobial, antioxidant and antitumor activity of ethanol extracts obtained from Phlomis russeliana (Sims.) Lag. ex Benth. (Lamiaceae) were evaluated. Disc diffusion and microdilution methods were used to test the extracts for antimicrobial activity against seven bacteria strains (Bacillus cereusATCC 7064, Bacillus subtilisATCC 6633, Staphylococcus aureusATCC 6538P, Escherichia coliATCC 10538, Proteus vulgarisATCC 6899, Salmonella typhimuriumCCM 5445 and Pseudomonas aeruginosaATCC 27853) and four yeast strains (Kluyveromyces fragilisATCC 8608, Rhodotorula rubraATCC 70403, Debaryomyces hanseniiDSM 70238 and Candida albicansATCC 10239). Notably, they were more effective against the yeast strains than the bacterial strains. Of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Phlomis russeliana; Antioxidant activity; Cytotoxic effect; Antimicrobial activity; Endemic plant. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000500604 |
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| Nascimento,Jeferson C.; Barbosa,Luiz C.A.; Paula,Vanderlucia F.; David,Jorge M.; Fontana,Renato; Silva,Luiz A.M.; França,Robson S.. |
| This work describes the chemical composition and antimicrobial activity of the volatile oils of Ocimum canum and Ocimum selloi, both occurring in Jequié/BA, northeastern Brazil. The plants were collected in the winter/2005 andsummer/2006, the oils extracted by steam distillation and further analyzed by GC-MS. A total of 30 and 31 compounds was identified from the oils of O. selloi and O. canum, respectively. It was observed that the oil content of O. canum showed variation during the seasons, while the oils of O. selloi did not. Methylchavicol and linalool were the main chemical components found in the aerial parts and leaves of O. canum. This finding permitted to characterize this specimen as a new chemotype of O. canum. Regarding the aerial parts of O.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antimicrobial activity; Essential oil; Lamiaceae; Ocimum canum; Ocimum selloi. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652011000300004 |
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| PEREIRA,RAFAEL; PEREIRA,ANNA L.; FERREIRA,MARCILIO M.; FONTENELLE,RAQUEL O.S.; SAKER-SAMPAIO,SILVANA; SANTOS,HÉLCIO S.; BANDEIRA,PAULO N.; VASCONCELOS,MAYRON A.; QUEIROZ,JOSÉ A.N.; BRAZ-FILHO,RAIMUNDO; TEIXEIRA,EDSON H.. |
| Abstract: This study evaluated the antibacterial, antifungal, and antioxidant effect of 7-hydroxy-4’,6-dimethoxy-isoflavone and essential oil of Myroxylon peruiferum. The compound was isolated and its structure elucidated by NMR. The chemical composition of essential oil determined by GC-MS analysis. To evaluation of antimicrobial activity, the Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC) and Minimum Fungicidal Concentration (MFC) were performed. In addition to analysis of antioxidant activity, DPPH radical scavenging tests, iron chelating assay (FIC), antioxidant reducing power assay (FRAP) and β-carotene bleaching assay (BCB) were performed. For the essential oil were identified 24 organized compounds having as main... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antimicrobial activity; Antioxidant activity; Essential oil; Isoflavone; Myroxylon peruiferum. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300602 |
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| Hossain,Mohammad Mobarak; Ahamed,Sayed Koushik; Dewan,Syed Masudur Rahman; Hassan,Md Mahadi; Istiaq,Arif; Islam,Mohammad Safiqul; Moghal,Md Mizanur Rahman. |
| BACKGROUND: The study was conducted to evaluate the in vitro antimicrobial activity, cytotoxic, and membrane stabilization activities, and in vivo antiemetic and antipyretic potentials of ethanolic extract, n-hexane and ethyl acetate soluble fractions of Spilanthes paniculata leaves for the first time widely used in the traditional treatments in Bangladesh. RESULTS: In antipyretic activity assay, a significant reduction (P < 0.05) was observed in the temperature in the mice tested. At dose 400 mg/kg-body weight, the n-hexane soluble fraction showed the effect (36.7 ± 0.63°C ) as like as the standard (dose 150 mg/kg-body weight) after 5 h of administration. Extracts showed significant (P < 0.001) potential when tested for the antiemetic activity... |
| Tipo: Journal article |
Palavras-chave: Antiemetic; Anti-inflammatory; Antimicrobial activity; Brine shrimp lethality bioassay; Cytotoxic; Membrane stabilization; Spilanthes paniculata. |
| Ano: 2014 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100045 |
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| AKINPELU,DA; ADEGBOYE,MF; ADELOYE,OA; OKOH,AI. |
| The in vitro antibacterial activity of crude methanolic extract of the seeds of Garcinia kola was investigated. The extracts exhibited antibacterial activities with zones of inhibition ranging from 10 mm to 25 mm. The minimum inhibitory concentration of the diethyl ether fraction was between 0.313 and 5.0 mg/ml, while that of butanol fraction varied from 0.157 to 5.0 mg/ml. The butanol fraction killed about 77% of Bacillus anthracis and 79% of Escherichia coli cells within 120 min at a concentration of 5.0 mg/ml. Protein leakage from the B. anthracis and E. coli cells when exposed to the butanol and diethyl ether fractions was observed. We conclude that Garcinia kola seed extract has a broad spectrum antibacterial activity, with the butanol and diethyl... |
| Tipo: Journal article |
Palavras-chave: Garcinia kola; Antimicrobial activity; MIC; Killing rate; Protein leakage. |
| Ano: 2008 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602008000300005 |
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| Cóndor-Luján,Báslavi; Francia-Quiroz,Juan C.. |
| ABSTRACT In the last decades, sponges have emerged as the largest source of active compounds of animal origin for pharmaceutical purposes. In Peru information on these animals is incipient and scattered, which limits taking the right measures for their adequate management, exploitation, and conservation. The aim of this study is to provide an update on the scope and perspectives of sponge research in Peru, with an emphasis on species richness and their antibacterial potential. Likewise, research initiatives carried out in other South American Pacific countries are reviewed. Research efforts in Peru have allowed the description of 46 species; however, the sponge richness is underestimated. On the other hand, in other latitudes, active principles with... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antimicrobial activity; Bacteria; Biotechnology; Marine biodiversity; Porifera.. |
| Ano: 2022 |
URL: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0122-97612022000200107 |
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| Martins,Mônica Cristina Barroso; Lima,Marcio James Gonçalves de; Silva,Flávia Pereira; Azevedo-Ximenes,Eulália; Silva,Nicácio Henrique da; Pereira,Eugênia Cristina. |
| The chemical composition and antimicrobial activity of the Cladia aggregata (Sw.) Nyl. were evaluated. Barbatic acid, depside obtained from C. aggregata, was spectroscopically analyzed and tested, as well as organic extracts. The extracts and purified substance were tested against four Staphylococcus aureus multi-resistant strains. The structure of barbatic acid was confirmed through NMR (¹H; 13C) and elemental ® analysis. Biochromatographic assays showed action of this compound, along with other substances contained in organic extracts, suggesting a synergic action, MIC assays placed barbatic acid in the same level of inhibition to other studied lichen substances. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cladia aggregata; Barbatic acid; Antimicrobial activity. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132010000100015 |
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| Registros recuperados: 104 | |
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