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| Gizachew Tiruneh. |
| *Objective:* To investigate the best statistical models that describe the effect of physical activity on BMI.
*Design:* Cross-sectional analyses of physical activity and BMI data.Subjects: 107 obese, overweight, and healthy college students (mean duration of physical activity for the normal, overweight, and obese students: 89, 59, and 24 months, respectively; mean BMI for the normal, overweight, and obese students: 21.61, 27.07, and 35.54 kg/m^2^, respectively).
*Measurements:* Inverse linear, inverse logarithmic, and inverse logistics models were used to analyze survey data for physical activity (measured by both frequency and duration of exercise) and BMI. Gender, age, and physical intensity variables were also... |
| Tipo: Manuscript |
Palavras-chave: Developmental Biology. |
| Ano: 2009 |
URL: http://precedings.nature.com/documents/2758/version/2 |
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| Rosario M. Ardito Marretta. |
| Experimental work and theoretical models deduce a "digital" response of the p53 transcription factor when genomic integrity is damaged. The mutual influence of p53 and its antagonist, the Mdm2 oncogene, is closed in feedback. This paper proposes an aerospace architecture for translating the p53/Mdm2/DNA damage network into a digital circuitry in which the optimal control theory is applied for obtaining the requested dynamic evolutions of some considered cell species for repairing a DNA damage. The purpose of this paper is not to improve the analysis of the actual mathematical models but to demonstrate the usefulness of such digital circuitry design capable to predict and detect the cell species dynamics for finding more information... |
| Tipo: Manuscript |
Palavras-chave: Biotechnology; Cancer; Developmental Biology. |
| Ano: 2009 |
URL: http://precedings.nature.com/documents/2870/version/1 |
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| Michael E. Baker. |
| 11[beta]-hydroxysteroid dehydrogenase type-2 (11[beta]-HSD2) regulates the local concentration of cortisol that can activate the glucocorticoid receptor and mineralocorticoid receptor, as well as the concentration of 11-keto-testosterone, the active androgen in fish. Similarly, 17[beta]-HSD2 regulates the levels of testosterone and estradiol that activate the androgen receptor and estrogen receptor, respectively. Interestingly, although human 11[beta]-HSD2 and 17[beta]-HSD2 act at different positions on different steroids, these enzymes are paralogs. Despite the physiological importance of 11[beta]-HSD2 and 17[beta]-HSD2, details of their origins and divergence from a common ancestor are not known. An opportunity to understand their evolution is... |
| Tipo: Manuscript |
Palavras-chave: Cancer; Developmental Biology; Pharmacology; Bioinformatics; Evolutionary Biology. |
| Ano: 2010 |
URL: http://precedings.nature.com/documents/4649/version/1 |
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| Vladimir L. Katanaev; Silke Buestorf. |
| Receptors of the Frizzled family initiate Wnt ligand-dependent signaling controlling
multiple steps in organism development and highly conserved in evolution.
Misactivation of the Wnt/Frizzled signaling is cancerogenic. Frizzled receptors
launch several signaling cascades: the canonical pathway regulating beta-catenin-dependent transcription; the planar cell polarity pathway polarizing the
cytoskeleton within the epithelial plane; and the calcium pathway. Frizzled
receptors possess seven transmembrane domains and their signaling depends on
trimeric G proteins in various organisms. However, Frizzleds constitute a
distinct group within the G... |
| Tipo: Manuscript |
Palavras-chave: Cancer; Developmental Biology; Molecular Cell Biology; Pharmacology. |
| Ano: 2009 |
URL: http://precedings.nature.com/documents/2765/version/1 |
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| Tracy Alloway; Ross Alloway. |
| Crystallized intelligence (Gc) is thought to reflect skills acquired through knowledge and experience and is related to verbal ability, language development^1^ and academic success^2^. Gc, together with fluid intelligence (Gf), are constructs of general intelligence^3^. While Gc involves learning, knowledge and skills, Gf refers to our ability in tests of problem-solving, pattern matching, and reasoning. Although there is evidence that Gf can be improved through memory training in adults^4^, the efficacy of memory training in improving acquired skills, such as Gc and academic attainment, has yet to be established. Furthermore, evidence of transfer effects from gains made in the trained tasks is sparse^5^. Here we demonstrate improvements in Gc and academic... |
| Tipo: Manuscript |
Palavras-chave: Developmental Biology. |
| Ano: 2009 |
URL: http://precedings.nature.com/documents/3697/version/1 |
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| John Skoyles. |
| A four year old child devotes half their total energy expenditure (TEE) to their brains. Even by 10 years-of-age it is still 30% (compared to an adult’s ≈12%). This extreme energy use results from a high brain/body size ratio – combined with a doubling of cerebral gray matter energy utilization (due to synaptic exuberance during cognitive neuromaturation). 

With extreme energy expenditure goes extreme vulnerability to hypoglycemia: (1) children become hypoglycemic after 24-36 hours of fast (compared to 60-72 hours in adults), and (2) their brains suffer neurological impairment (shown in disrupted P300 potentials) at a lower decrease in plasma glucose: 3.6 - 4.2 mmol L-1 in children rather... |
| Tipo: Presentation |
Palavras-chave: Developmental Biology; Neuroscience; Evolutionary Biology. |
| Ano: 2012 |
URL: http://precedings.nature.com/documents/7097/version/1 |
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| Amanda J. Twomey; Bodapati P. Naidu; Shu Fukai. |
| It has been observed that _Melaleuca cuticularis_ Labill. has the ability to secrete salt solution to the surface of its stem. No literature has been found to illustrate other species' capacity to secrete salts at the stem and with what little literature there is on _M. cuticularis_ under saline conditions ^1, 2^, there was no evidence documented by those authors to have witnessed salt secreting at the stem. Most recorded observations of salt secretion by plants has usually been on leaf salt secretion through specialized glands or bladders often in mangroves, salt bushes and grass species, among others ^3-8^. This observation is the first known record of a plant species capable of secreting salts mostly at the stem. |
| Tipo: Manuscript |
Palavras-chave: Developmental Biology; Earth & Environment; Plant Biology. |
| Ano: 2008 |
URL: http://precedings.nature.com/documents/2450/version/1 |
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| Dennis Richard LaJeunesse; Brooke Ann Johnson; Jason Presnell; Kathleen K. Catignas; Grzegorz Zapotoczny. |
| The underlying cellular and molecular mechanisms that regulate and coordinate critical physiological processes such as peristalsis are complex, often cryptic, and involve the integration of multiple tissues and organ systems within the organism. We have identified a completely novel component of the larval autonomic nervous system in the _Drosophila_ larval midgut that is essential for the peristaltic movement of food from the anterior midgut into the acidic region of the midgut. We have named this region the Superior Cupric Autonomic Nervous System or SCANS. Located at the junction of the anterior and the acidic portions of the midgut, the SCANS is characterized by a cluster of a novel neuro-enteroendocrine cells that we call Lettuce Head Cells, a valve,... |
| Tipo: Manuscript |
Palavras-chave: Developmental Biology; Neuroscience. |
| Ano: 2009 |
URL: http://precedings.nature.com/documents/3873/version/1 |
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| Raji Heyrovska; Saraswathi Narayan; Lakshmi Atchison. |
| This work celebrates the “International Year of Chemistry – 2011”, by providing “for the first time”, the structures at the atomic level of two important molecules, namely, ascorbic acid and aspirin. Ascorbic acid, also known as vitamin C, was discovered as a cure for scurvy which claimed many human lives and hence got its name. It is also supposed to be an antioxidant and to prevent flu. Aspirin is synthesized from salicylic acid and is widely used as a remedy for flu and has other medical uses such as saving the lives of cardiac patients as an anticoagulant of blood. The biochemistry and chemistry of both these compounds have been evolving for nearly a century ever since their discoveries. Here, the... |
| Tipo: Poster |
Palavras-chave: Chemistry; Developmental Biology; Bioinformatics. |
| Ano: 2011 |
URL: http://precedings.nature.com/documents/5966/version/1 |
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| Rodrick Wallace. |
| We extend a cognitive paradigm for gene expression to the epigenetic epidemiology of mental disorders, recognizing the fundamental role that culture plays in human biology as another heritage mechanism parallel to, and interacting with, the more familiar genetic and epigenetic systems. In the mathematical model, culture acts as another tunable epigenetic catalyst that both directs developmental trajectories and becomes convoluted with individual ontology via a mutually interacting crosstalk mediated by a social interaction that is itself culturally driven. We call for the incorporation of embedding culture as an essential component of the epigenetic regulation of human mental development and its dysfunctions, bringing what is perhaps the central reality of... |
| Tipo: Manuscript |
Palavras-chave: Developmental Biology; Genetics & Genomics; Neuroscience. |
| Ano: 2009 |
URL: http://precedings.nature.com/documents/3894/version/2 |
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| Susana A. Miyahira; Joao L. M. C. Azevedo; José E. Araujo Filho. |
| Background: A fuzzy obesity index (MAFOI) for use as an alternative to bariatric surgery indication (BSI) is presented. The search for a more accurate method to evaluate obesity and to indicate a better treatment is important in the world health context. BMI (body mass index) is considered the main criteria for obesity treatment and BSI. Nevertheless, the fat excess related to the percentage of Body Fat (%BF) is actually the principal harmful factor in obesity disease that is usually neglected. This paper presents a new fuzzy mechanism for evaluating obesity by associating BMI with %BF that yields a fuzzy obesity index for obesity evaluation and treatment and allows building up a Fuzzy Decision Support System (FDSS) for BSI. Methods: Seventy-two patients... |
| Tipo: Manuscript |
Palavras-chave: Developmental Biology; Molecular Cell Biology. |
| Ano: 2011 |
URL: http://precedings.nature.com/documents/5516/version/2 |
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| Registros recuperados: 193 | |
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