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Registros recuperados: 46
Primeira ... 123 ... Última
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Synergistic effects of sulbactam in multi-drug-resistant Acinetobacter baumannii BJM
Temocin,Fatih; Erdinc,Fatma Sebnem; Tulek,Necla; Demirelli,Meryem; Ertem,Gunay; Kinikli,Sami; Koksal,Eda.
Abstract Acinetobacter baumannii is a frequently isolated etiologic agent of nosocomial infections, especially in intensive care units. With the increase in multi-drug resistance of A. baumannii isolates, finding appropriate treatment alternatives for infections caused by these bacteria has become more difficult, and available alternate treatments include the use of older antibiotics such as colistin or a combination of antibiotics. The current study aimed to evaluate the in vitro efficacy of various antibiotic combinations against multi-drug resistant A. baumannii strains. Thirty multi-drug and carbapenem resistant A. baumannii strains isolated at the Ankara Training and Research Hospital between June 2011 and June 2012 were used in the study. Antibiotic...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acinetobacter; Antimicrobial drugs; Drug resistance; Drug synergism.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000401119
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Emergence of fluoroquinolone-resistant Neisseria gonorrhoeae in São Paulo, Brazil BJM
Belda Junior,Walter; Velho,Paulo Eduardo Neves Ferreira; Arnone,Marcelo; Fagundes,Luis Jorge.
Continued monitoring of antimicrobial resistance patterns is essential in order for Sexually Transmitted Diseases (STD) treatment to be effective. Gonococci isolates from 65 patients in São Paulo were submitted to susceptibility testing, and a decreased susceptibility or resistance to ciprofloxacin was observed in 8.7% of these patients, indicating that Neisseria gonorrhoeae fluoroquinolone resistance is emerging in Brazil.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Anti-bacterial agents; Ciprofloxacin; Drug resistance; Neisseria gonorrhoeae.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822007000200020
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AmpC beta lactamases among Gram negative clinical isolates from a tertiary hospital, South India BJM
Mohamudha,Parveen R.; Harish,B.N.; Parija,S.C..
AmpC β-lactamases are cephalosporinases that hydrolyze cephamycins as well as other extended-spectrum cephalosporins and are poorly inhibited by clavulanic acid. Although reported with increasing frequency, the true rate of occurrence of AmpC β-lactamases in different organisms, including members of Enterobacteriaceae, remains unknown. The present study was designed to determine the occurrence of AmpC enzyme-harbouring Gram-negative clinical isolates in a tertiary care hospital in Pondicherry state, South India. A total of 235 Gram negative clinical isolates were tested for resistance to cefoxitin, third generation cephalosporin (3GC) antibiotics, ampicillin, amikacin, co-trimoxazole, gentamicin, meropenem and tetracycline by disc diffusion method....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Gram negative organisms; Drug resistance; Three-dimensional technique; AmpC β-lactamases.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822010000300009
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Multiple drug resistance patterns in various phylogenetic groups of uropathogenic E.coli isolated from Faisalabad region of Pakistan BJM
Bashir,Saira; Sarwar,Yasra; Ali,Aamir; Mohsin,Mashkoor; Saeed,Muhammad Azeem; Tariq,Ayesha; Haque,Abdul.
The objective of this work was the phylogenetic characterization of local clinical isolates of uropathogenic E. coli with respect to drug resistance. A total of 59 uropathogenic E. coli responsible for community acquired urinary tract infections were included in this study. A triplex PCR was employed to segregate each isolate into four different phylogenetic groups (A, B1, B2 and D). Drug resistance was evaluated by disc diffusion method. The drugs used were ampicillin, aztreonam, cefixime, cefoperazone, ceftriaxone, cephradine among β-lactam group; amikacin, gentamicin, and streptomycin among aminoglycosides; nalidixic acid and ciprofloxacin from quinolones; trimethoprim-sulfomethoxazole, and tetracycline. Among 59 uropathogenic E. coli isolates majority...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Uropathogenic E. coli; Phylogenetic analysis; Drug resistance.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822011000400005
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Comparative evaluation of the Nitrate Reductase Assay and the Resazurin Microtitre Assay for drug susceptibility testing of Mycobacterium tuberculosis against first line anti-tuberculosis drugs BJM
Sanchotene,Karine O.; von Groll,Andrea; Ramos,Daniela; Scholante,Ana B.; Honscha,Gunther; Valença,Mariana; Scaini,Carlos J.; Silva,Pedro E.A. da.
Tuberculosis remains as a serious infection disease of worldwide distribution, with high morbidity and mortality, mainly in low socio-economic condition countries. The state of emergency of tuberculosis caused by the resistant and multidrug-resistant (MDR) strains, became the main threat to the tuberculosis treatment and control programs. A fast detection method for the resistant strains will allow the implementation of an adequate treatment and contribute for controlling the dissemination of these resistant strains. This study evaluated the performance of the nitrate reductase assay in solid (NRA-LJ) and liquid (NRA-7H9) media, to determine the susceptibility to first line anti-tuberculosis drugs: isoniazid (INH), rifampicin (RMP), ethambutol (EMB) and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Tuberculosis; Mycobacterium tuberculosis; Nitrate reductase assay; Susceptibility tests; Drug resistance.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822008000100004
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HIV-1 subtypes and mutations associated to antiretroviral drug resistance in human isolates from Central Brazil BJM
Cerqueira,Daniela Marreco; Ramalho,Eduardo Dias; Oliveira,Claudiner Pereira; Silva,Ruiter Roberto; Franchini,Miriam; Felipe,Maria Sueli Soares; Martins,Cláudia Renata Fernandes.
The detection of polymorphisms associated to HIV-1 drug-resistance and genetic subtypes is important for the control and treatment of HIV-1 disease. Drug pressure selects resistant variants that carry mutations in the viral reverse transcriptase (RT) and protease (PR) genes. For a contribution to the public health authorities in planning the availability of therapeutic treatment, we therefore described the genetic variability, the prevalence of mutations associated to drug resistance and the antiretroviral resistance profile in HIV-1 isolates from infected individuals in Central Brazil. Nineteen HIV-1 RNA samples from a Public Health Laboratory of the Federal District were reversely transcribed and cDNAs were amplified by nested PCR. One fragment of 297 bp...
Tipo: Info:eu-repo/semantics/article Palavras-chave: HIV-1; Drug resistance; Antiretroviral drugs.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822004000200003
Registros recuperados: 46
Primeira ... 123 ... Última
 

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