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| Registros recuperados: 53 | |
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| ARREDONDO,MIGUEL; MARTÍNEZ,RONNY; NÚÑEZ,MARCO T; RUZ,MANUEL; OLIVARES,MANUEL. |
| Interactions of micronutrients can affect absorption and bioavailability of other nutrients by a number of mechanisms. In aqueous solutions, and at higher uptake levels, competition between elements with similar chemical characteristics and uptake process can take place. The consequences of these interactions may depend on the relative concentrations of the nutrients. In this work, we measure the effects of increasing concentrations of iron, zinc, and copper on iron and copper uptake in Caco-2 cells. Intracellular Fe or Cu levels were affected by incubating with increased concentrations of metals. However, when the cells already had different intracellular metal concentration, the uptake of Fe or Cu was nor affected. In competition studies, we showed that... |
| Tipo: Journal article |
Palavras-chave: Competition; Interaction; Metals; Uptake. |
| Ano: 2006 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602006000100011 |
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| Patel,Satish D.; Sadariya,Kamlesh A.; Gothi,Anil K.; Patel,Urvesh D.; Gohil,Pradhuman A.; Jain,Mukul R.; Bhavsar,Shailesh K.; Thaker,Aswin M.. |
| Pharmacokinetics of tolfenamic acid as a single drug (4 mg/kg, intramuscularly) and its co-administration with moxifloxacin (5 mg/kg, intramuscularly) in wistar rats were studied. The plasma drug concentration of tolfenamic acid was assayed by LC-MS/MS. Following intramuscular administration of tolfenamic acid as single drug and in combination with moxifloxacin in male rats, the mean values of observed peak plasma drug concentration (Cmax), area under plasma drug concentration-time curve (AUC(0-¥) ), volume of distribution (Vz), half-life (t½) and clearance (Cl) were 4111.44 ± 493.15 and 3837.69 ± 351.83 ng/ml, 20280.77 ± 3501.67 and 15229.18 ± 678.80 ng.h/ml, 822.17 ± 115.38 and 1249.64 ± 139.52 ml, 2.59 ± 0.16 and 3.27 ± 0.32 hr, and 218.39 ± 25.47 and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Pharmacokinetics; Tolfenamic acid; Anti inflammatory drug; Rats; Interaction; Moxifloxacin. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000400013 |
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| Erhardt,E.; Zibetti,L.C.E.; Godinho,J.M.; Bacchieri,B.; Barros,H.M.T.. |
| The objective of the present study was to determine if the acute behavioral effects of cocaine acutely administered intraperitoneally (ip) at doses of 5, 10 and 20 mg/kg on white male CF1 mice, 90 days of age, would be influenced by leptin acutely administered ip (at doses of 5, 10 and 20 µg/kg) or by endogenous leptin production enhanced by a high-fat diet. The acute behavioral effects of cocaine were evaluated in open-field, elevated plus-maze and forced swimming tests. Results were compared between a group of 80 mice consuming a balanced diet and a high-fat diet, and a group of 80 mice fed a commercially available rodent chow formula (Ralston Purina) but receiving recombinant leptin (rLeptin) or saline ip. Both the high-fat-fed and rLeptin-treated mice... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Mice; Cocaine; Leptin; Hyperlipidic diet; Interaction. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006001200014 |
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| Escobar,Magaly; Berti,Marisol; Matus,Iván; Tapia,Maritza; Johnson,Burton. |
| Genotype x environment (G × E) interaction in canola (Brassica napus L.) cultivar seed yield is unknown in Chile. The interaction was performed with the SREG (Sites Regression) model. Two experiments were conducted in five and thirteen environments in the 2008-2009 season in Central South Chile. The experimental design was a randomized complete block (RCBD) in each environment with four replicates and 26 open-pollinated or hybrid canola genotypes in Experiment 1, and RCBD with three replicates and 17 genotypes in Experiment 2. ANOVA was used to determine the significance of the G × E interaction. biplots were used to graphically interpret and determine the best cultivar in each environment and the corresponding mega-environments. The G × E interaction was... |
| Tipo: Journal article |
Palavras-chave: SREG; GGE; MET; Interaction; Biomass. |
| Ano: 2011 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-58392011000200001 |
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| Dorneles,Athos Odin Severo; Pereira,Aline Soares; Rossato,Liana Verônica; Possebom,Gessieli; Sasso,Victória Martini; Bernardy,Katieli; Sandri,Ruziele de Quadros; Nicoloso,Fernando Teixeira; Ferreira,Paulo Ademar Avelar; Tabaldi,Luciane Almeri. |
| ABSTRACT: Aluminum (Al) is highly toxic to plants, causing stress and inhibiting growth and silicon (Si) is considered beneficial for plants. This chemical element has a high affinity with Al. The aim of this study was to investigate the potential of Si to mitigate the toxic effects of Al on potato ( Solanum tuberosum L.) plants and assess whether this behavior is different among genotypes with differing degrees of sensitivity to Al. Potato plants of the genotypes SMIJ319-7 (Al-sensitive) and SMIF212-3 (Al-tolerant) were grown for fourteen days in nutrient solution (without P and pH 4.5±0.1) under exposure to combinations of Al (0 and 1.85mM) and Si (0, 0.5 and 1.0mM). After this period, shoot and roots of the two genotypes were collected to determine Al... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Solanum tuberosum; Beneficial element; Toxic element; Interaction. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782016000300506 |
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| Registros recuperados: 53 | |
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