|
|
|
| Registros recuperados: 56 | |
|
|
| SOUSA,WENDEL C. DE; T.S. PAZ,ANDRESSA; ROCHA,JAMIRA D.; CONCEIÇÃO,EDEMILSON C. DA; ALMEIDA,LUCIANE M. DE; CHEN,LEE C.; BORGES,LEONARDO L.; BAILÃO,ELISA F.L.C.. |
| ABSTRACT Costus spiralis is a Brazilian native plant used in popular medicine, but the safety of this therapeutic use needs investigation. So, the aim of this study was to evaluate the cytogenotoxic and antigenotoxic effects of C. spiralis leaves or stems aqueous extracts on Allium cepa root cells. Moreover, a phytochemical screening and an antioxidant and antifungal activities evaluation were performed. C. spiralis aqueous extracts presented cytotoxicity, but no mutagenicity was observed. When the antigenotoxicity was evaluated, C. spiralis leaves aqueous extract presented preventive and modulatory effects on A. cepa root cells, reducing the sodium azide cytogenotoxic effects. In contrast, C. spiralis stems aqueous extract enhanced the sodium azide... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Allium cepa test; Antioxidant; Medicinal plant; Secondary metabolites. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000401565 |
| |
|
|
| Paiva,Selma R.; Lima,Lucilene A.; Figueiredo,Maria Raquel; Kaplan,Maria Auxiliadora C.. |
| Plumbago scandens L. is a Brazilian tropical/subtropical species that occurs along the coast. Chemically it is mainly represented by naphthoquinones, flavonoids, terpenoids and steroids. The aim of the present work is to study quantitative changes in the root metabolic production of Plumbago scandens during different physiologic developmental stages relative to floration. The results indicated the presence of four substances in the extracts: plumbagin, epi-isoshinanolone, palmitic acid and sitosterol, independent on developmental stage. The naphthoquinone plumbagin has always showed to be the major component of all extracts. Naphthoquinones exhibited their highest content during floration, while the content of the two others components decreased during... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: GC/MS; Plant physiology; Plubaginaceae; Secondary metabolites. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652011000400004 |
| |
|
| |
|
| |
|
|
| Menezes,C.B.A.; Silva,B.P.; Sousa,I.M.O.; Ruiz,A.L.T.G.; Spindola,H.M.; Cabral,E.; Eberlin,M.N.; Tinti,S.V.; Carvalho,J.E.; Foglio,M.A.; Fantinatti-Garboggini,F.. |
| Natural products produced by microorganisms have been an important source of new substances and lead compounds for the pharmaceutical industry. Chromobacterium violaceum is a Gram-negative β-proteobacterium, abundant in water and soil in tropical and subtropical regions and it produces violacein, a pigment that has shown great pharmaceutical potential. Crude extracts of five Brazilian isolates of Chromobacterium sp (0.25, 2.5, 25, and 250 µg/mL) were evaluated in an in vitro antitumor activity assay with nine human tumor cells. Secondary metabolic profiles were analyzed by liquid chromatography and electrospray ionization mass spectrometry resulting in the identification of violacein in all extracts, whereas FK228 was detected only in EtCE 308 and EtCE 592... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Chromobacterium sp; Antitumor activity; Secondary metabolites; Genetic diversity; Violacein. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000100065 |
| |
|
| |
|
|
| Banhos,Elissandro Fonseca dos; Souza,Antonia Queiroz Lima de; Andrade,Juliano Camurça de; Souza,Afonso Duarte Leão de; Koolen,Hector Henrique Ferreira; Albuquerque,Patrícia Melchionna. |
| Beneficial interactions between plants and microorganisms have been investigated under different ecological, physiological, biochemical, and genetic aspects. However, the systematic exploration of biomolecules with potential for biotechnological products from this interaction still is relatively scarce. Therefore, this study aimed the evaluation of the diversity and antimicrobial activity of the endophytic fungi obtained from roots, stems and leafs of Myrcia guianensis (Myrtaceae) from the Brazilian Amazon. 156 endophytic fungi were isolated and above 80% were identified by morphological examination as belonging to the genera Pestalotiopsis, Phomopsis, Aspergillus, Xylaria, Nectria, Penicillium and Fusarium. Fermented broth of those fungi were assayed for... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Secondary metabolites; Fungus/plant interaction; Antibiosis; Amazonian endophytic fungi. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000100021 |
| |
|
| |
|
|
| Rosa,Luiz H.; Gonçalves,Vívian N.; Caligiorne,Rachel B.; Alves,Tânia M. A.; Rabello,Ana; Sales,Policarbo A.; Romanha,Alvaro J.; Sobral,Marcos E. G.; Rosa,Carlos A.; Zani,Carlos L.. |
| One hundred and twenty-one isolates of endophytic fungi were recovered from leaves of the bioactive Brazilian plant species Ageratum myriadenia, Palicourea tetraphylla, Piptadenia adiantoides, and Trixis vauthieri. All fungal isolates were cultivated in liquid media and crude extracts were obtained with ethyl acetate. The crude extracts were tested in bioassay panels using Leishmania amazonensis, Trypanosoma cruzi, the enzyme trypanothione reductase (TryR) from Trypanosoma cruzi, and three human cancer cell lines. Thirty-three extracts (27.2%) exhibited at least one biological activity. Seventeen extracts (14%) were cytotoxic against one or more human cancer cell line with the IC50 values ranged of >0.2 to 25 µg/mL. Twenty-four extracts (19.8%)... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Endophytic fungi; Human tumoral cell; Leishmania; Secondary metabolites; Trypanosoma cruzi. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822010000200024 |
| |
|
|
| Soares,Ana Cristina Fermino; Sousa,Carla da Silva; Garrido,Marlon da Silva; Perez,Jane Oliveira; Almeida,Nailson Santos de. |
| Yam (Dioscorea cayennensis Lam), an important crop in the Northeastern region of Brazil, is susceptible to the attack of several phytopathogenic fungi, such as Curvularia eragrostides (Henn.) Meyer and Colletotrichum gloeosporioides (Penz.), which cause leaf spot diseases. This work aimed to evaluate the effect of six actinomycete isolates (S. thermotolerans, S. griseus subsp. griseus, Streptomyces sp. N0035, S. purpurascens, and two isolates identified as Streptomyces sp.), as well as the effect of their secondary metabolites, on mycelium growth and spore germination of C. eragrostides and C. gloeosporioides, from yam plants, cultivar da Costa. Additionally, the chitinolytic activity of these actinomycete strains was determined in a minimum salt growth... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Biocontrol; Dioscorea cayennensis; Actinomycetes; Secondary metabolites. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822006000400010 |
| |
|
|
| Silva,Joanda Paolla Raimundo e; Reis,Malu Maria Lucas dos; Santana,Cleildo Pereira; Medeiros,Ana Cláudia Dantas de; Alves,Harley da Silva. |
| Tacinga inamoena (K. Schum.) N.P. Taylor & Stuppy, also known as quipá, is a native cactus of the Caatinga used in traditional medicine to treat urethral infections and inflammation. This study aimed to determine the physicochemical characteristics of vegetal drug obtained from the roots of T. inamoena. Analytical techniques and phytochemical tests were used, such as thermal analysis, qualitative and semiquantitative determination of secondary metabolites and spectroscopy at the infrared region. The powder of the vegetal drug met the parameters established by the Brazilian Pharmacopoeia, except for compressibility, which was low. On the thermogravimetric curve, three events related to the mass loss were verified, which correlate with the vegetal drug... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cactaceae; Quality control; Herbal medicine; Secondary metabolites; Thermogravimetry. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100602 |
| |
|
|
| Silva,Maicon F. da; Pescador,Rosete; Rebelo,Ricardo A.; Stürmer,Sidney L.. |
| We have investigated the effects of phosphate fertilization and inoculation with isolates of arbuscular mycorrhizal fungi Scutellospora heterogama SCT120E, Gigaspora decipiens SCT304A, Acaulospora koskei SCT400A, Entrophospora colombiana SCT115, and an assemblage (Mix) of all four isolates on growth, development and oleoresin production of micropropagated Zingiber officinale. After 120 and 210 d of growth, the Mix and phosphorus addition significantly increased shoot height relative to control plants. Phosphorus addition was the only treatment resulting in significantly large shoot dry biomass relative to control after 120 d. No statistical differences were observed between treatments for shoot dry biomass after 210 d and for fine and coarse root biomass... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Fungal assemblage; Ginger; Oleoresin; Secondary metabolites. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-04202008000200004 |
| |
|
|
| Rebolledo,Ramón; Abarzúa,Juan; Zavala,Andrea; Quiroz,Andrés; Alvear,Marysol; Aguilera,Alfonso. |
| Drimys winteri (Magnoliids: Winteraceae), a native Chilean species, has potential for use as a botanical insecticide. This species contains chemicals with biological activity, such as isoprenoids and polyphenols. In this study, the effects of the essential oil and hydrolate of D. winteri on adults of Aegorhinus superciliosus were determined in the laboratory. This species is one of the most important pests associated with the cultivation of blueberries in Chile. The insecticidal effect of both distillates was determined for five concentrations of the essential oil and hydrolate of D. winteri, with ten replicates, in a completely random bioassay. The effects of these preparations on the egg-laying, hatching and feeding activity of A. superciliosus were also... |
| Tipo: Journal article |
Palavras-chave: Essential oil; Hydrolate; Secondary metabolites. |
| Ano: 2012 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-16202012000300008 |
| |
|
| |
|
|
| Rossi,Natalia Hoffmann; Oliveira,Maurício Schneider; Wovst,Liziane Rachel da Silva; Mallmann,Carlos Augusto. |
| ABSTRACT: Purple maize is an important foodstuff for the Peruvian people. Its unique nutritional and antioxidant characteristics makes it widely exported to other countries. However, when contaminated by fungi, it can trigger numerous health problems in the consumers. This study aimed to evaluate the presence of 27 mycotoxins in 63 samples of purple maize collected in Peru. Frequency of occurrence and mean concentration of the following mycotoxins were determined: alternariolmetileter (AME), alternariol (AOH), tentoxin, neosolaniol, nivalenol, wortmannin, deoxynivalenol, 3-acetyl deoxynivalenol, 15-acetyl deoxynivalenol, zearalenone, aflatoxin B1, aflatoxin B2, aflatoxin G1, aflatoxin G2, fumonisin B1, fumonisin B2, fumonisin B3, ochratoxin A, ochratoxin... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Zea mays L; Alternariolmetileter; Alternariol; Secondary metabolites. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782019001100753 |
| |
|
|
| Valduga,Alice Teresa; Gonçalves,Itamar Luís; Dartora,Nessana; Mielniczki-Pereira,Albanin Aparecida; Souza,Lauro Mera de. |
| ABSTRACT Yerba-mate (Ilex paraguariensis St. Hil) is a native South American species. Plant progenies are populations that differ in terms of their productivity, morphology and phytochemical profile. This study aimed to determine the concentration of primary and secondary metabolites, such as antioxidants, in leaves, of yerba-mate progenies selected based on morphological characteristics. We evaluated the centesimal composition of secondary metabolites in the leaves of five yerba-mate plants. Methylxanthines and phenolic compounds were determined by UPLC-PDA, and antioxidant activity by measuring DPPH scavenging. Significant differences were found in centesimal composition and the contents of caffeine, theobromine, rutin and chlorogenic acid, as well as... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ilex paraguariensis St. Hil.; Plant selection; Secondary metabolites. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-70542016000100114 |
| |
| Registros recuperados: 56 | |
|
|
|
