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| Registros recuperados: 183 | |
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| Azadbakht, Mohsen; Jafarzadeh, Sajad; Varasteh, Faryal; Vahedi Torshizi, Mohammad. |
| This study was conducted considering the high importance of persimmon's chemical properties and the effect of different factors on its variations during storage and maintaining period. This study attempted to investigate some cases such as the effect of compressive loading parameters at 2 levels of 150 N and 250 N, three types of foam container packaging with polyolefin film, polyethylene terephthalate, and ordinary box and four types of putrescine polyamine coating with concentrations of 1 mM and 2 mM, distilled water and uncoated state, the chemical properties of persimmon fruit including the number of antioxidants, total phenol, flavonoids, vitamin C, pH, acidity and dissolved solids. The results showed that the highest content of total phenol and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Persimmon; Coating; Packaging; Antioxidant; Vitamin C. |
| Ano: 2022 |
URL: http://www.cigrjournal.org/index.php/Ejounral/article/view/7291 |
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| Mello,Sônia A.; Marese,Angélica C.M.; Brancalhão,Rose M.C.; Zanoni,Jacqueline N.; Natali,Maria Raquel M.. |
| During the ageing process the enteric nervous system undergoes morphofunctional changes, such as enteric neurodegeneration. Neuronal death can be attributed to increase radicals free, and ascorbic acid (AA), known antioxidant, could minimize damage cause by oxidative stress. The objective of this study is to analyse the behaviour of morphoquantative myenteric neurons in the duodenum of adult Wistar rats with aged 90 (C90), 345 (E345) and 428 (E428) days, as well as animals of the same age who received ascorbic acid supplementation for 120 days (EA345 and EA428). Whole-mount preparations of muscle layer from the duodenum of the animals were immunostained by the method myosin V. 80 microscopic fields were quantified (14.8 mm2/animal) and measured 100... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Aging; Antioxidant; Enteric nervous system; Immunohistochemistry. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652013000100337 |
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| GIUSTINA,AMANDA D.; DANIELSKI,LUCINÉIA G.; NOVOCHADLO,MICHELE M.; GOLDIM,MARIANA P.S.; JOAQUIM,LARISSA; METZKER,KIUANNE L.L.; CARLI,RAQUEL JACONI DE; DENICOL,TAIS; CIDREIRA,THAINA; VIEIRA,THAYNAN; PETRONILHO,FABRICIA. |
| Abstract Abstract: Sepsis is a life-threatening organ dysfunction induced by a disrupted host response to infecting pathogens. Inflammation and oxidative stress are intrinsically related to sepsis progression and organ failure. Vitamin B6 is an important cellular cofactor for metabolic processes and has anti-inflammatory and antioxidant properties. We aimed at evaluating the effect of vit B6 on inflammation and oxidative stress markers in the liver and lung of rats subjected to a relevant animal model of polymicrobial sepsis. Adult male Wistar rats were submitted to cecal ligation and perforation model and immediately after sepsis induction, vit B6 was administered as a single dose (600 mg/kg, subcutaneous). Twenty-four hours later, the lung and liver... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Sepsis; Vitamin B6; Oxidative stress; Antioxidant. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000700627 |
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| ALBUQUERQUE,DANIEL M.N.; LOPES,JOÃO B.; FERRAZ,MAÍRA S.; RIBEIRO,MABELL N.; SILVA,SANDRA R.G.; COSTA,ELVÂNIA M.S.; LIMA,DANIELA C.P.; FERREIRA,JEFFERSON D.M.; GOMES,PEDRO E.B.; LOPES,JACKELLINE C.O.. |
| ABSTRACT This study was conducted to evaluate the effect of vitamin E and selenium on performance, viability, productive efficiency, and yields of carcass, major cuts, and organs of broilers from 22 to 42 days submitted to cyclic-heat stress. The experimental design was randomized blocks, in a 2 × 3 factorial arrangement with two levels of selenium (0.1 and 0.3 mg/kg) and three levels of vitamin E (300, 400, and 500 mg/kg), plus a control treatment. Animals were submitted to a natural condition of high cyclic temperature. Organic selenium levels of 0.1 and 0.3 mg/kg associated with 300, 400, and 500 mg/kg of vitamin E were tested. The level of vitamin E did not affect the performance or production efficiency of broilers in the period from 22 to 33 days and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antioxidant; Minerals; Nutrition; Poultry; Productive efficiency; Vitamins. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000301259 |
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| ALENCAR,DANIEL B. DE; SILVA,SUZETE R. DA; PIRES-CAVALCANTE,KELMA M.S.; LIMA,REBECA L. DE; PEREIRA JÚNIOR,FRANCISCO N.; SOUSA,MÁRCIA B. DE; VIANA,FRANCISCO A.; NAGANO,CELSO S.; NASCIMENTO,KYRIA S. DO; CAVADA,BENILDO S.; SAMPAIO,ALEXANDRE H.; SAKER-SAMPAIO,SILVANA. |
| Natural antioxidants found in marine macroalgae are bioactive compounds known to play an important role in the prevention of diseases associated with aging cells protecting them against the oxidative damage. The purpose of this study was to evaluate the antioxidant and cytotoxic activity of ethanolic extracts of two species of red seaweeds, Amansia multifida and Meristiella echinocarpa. In vitro antioxidant activity was determined by DPPH radical scavenging assay, ferric-reducing antioxidant power (FRAP) assay, ferrous ion chelating (FIC) assay, β-carotene bleaching (BCB) assay and total phenolic content (TPC) quantification. Cytotoxicity was evaluated with the brine shrimp Artemia sp. lethality test. The TPC values observed in the present study indicated... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antioxidant; Bioactive compounds; Cytotoxic; Phenolic compounds; Rhodophyta. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652014000100251 |
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| WILHELM,ETHEL A.; FERREIRA,ANA TERESINHA; PINZ,MIKAELA P.; REIS,ANGÉLICA S. DOS; VOGT,ANE G.; STEIN,ANDRE L.; ZENI,GILSON; LUCHESE,CRISTIANE. |
| ABSTRACT The present study investigated the antioxidant effect of a new class of quinoline derivatives (a-d) on assays in vitro. Lipid peroxidation, thiol peroxidase-like and free radical scavenging activities were determined to evaluate antioxidant activity of compounds. Thiol oxidase-like and δ-aminolevulinate dehydratase activities were performed as a toxicological parameter. A second objective of this study was to evaluate the in vivo antinociceptive effect of the compound with better antioxidant effect and without toxic effects in a model of nociception induced by formalin in mice. In liver, at 100 µM, compound a reduced the lipid peroxidation to the control levels, while compounds c and d partially reduced it. In brain, only compound d partially... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antinociceptive; Antiedematogenic; Anti-inflammatory; Antioxidant; Quinoline. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000200457 |
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| HAKIME-SILVA,RICARDO A.; VELLOSA,JOSÉ C.R.; KHALIL,NAJEH M.; KHALIL,OMAR A.K.; BRUNETTI,IGUATEMY L.; OLIVEIRA,OLGA M.M.F.. |
| Mushrooms possess nutritional and medicinal properties that have long been used for human health preservation and that have been considered by researchers as possible sources of free radical scavengers. In this work, the antioxidant properties of water extracts from Agaricus blazei Murill, produced by maceration and decoction, are demonstrated in vitro. Resistance to oxidation is demonstrated through three mechanisms: i) inhibition of enzymatic oxidative process, with 100% inhibition of HRP (horseradish peroxidase) and MPO (myeloperoxidase); ii) inhibition of cellular oxidative stress, with 80% inhibition of the oxidative burst of polymorphonuclear neutrophils (PMNs); and iii) direct action over reactive species, with 62% and 87% suppression of HOCl and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Agaricus blazei Murrill; Antioxidant; Oxidant species; Chemiluminescence; Polymorphonuclear neutrophils. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652013000301073 |
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| BOLIGON,ALINE A.; PIANA,MARIANA; BRUM,THIELE F. DE; FROEDER,AMANDA L.F.; BELKE,BIANCA V.; SCHWANZ,THIAGO G.; MARIO,DÉBORA N.; ALVES,SYDNEY H.; ATHAYDE,MARGARETH L.. |
| The volatile oil from the stem bark of Scutia buxifolia (Rhamnaceae) has been obtained by hydrodistillation and analyzed by GC-MS. Twenty-one components were identified representing 99.93 % of the total oil composition, spathulenol (35.87%), β-cubebene (17.26%), germacrene D (6.43%), linalool (5.19%), carvacrol (4.05%) were the main components of S. buxifolia essential oil. Antioxidant and antimicrobial properties of the essential oil were evaluated by free radical scavenging (DPPH) assay and micro broth dilution method, respectively. S. buxifolia essential oil presented interesting radical scavenging activity (IC50 = 15.03 ± 0.11 µg/mL). The antibacterial assay showed that S. buxifolia stem bark essential oil was moderately active against the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Scutia buxifolia; Essential oil; Antioxidant; Antimicrobial. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652014000301463 |
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| Rodrigues,Patrícia A.; Morais,Selene M.; Souza,Carolina M.; Magalhães,Davi V.; Vieira,Ícaro G.P.; Andrade,Geanne M.; Rao,Vietla S.; Santos,Flávia A.. |
| Byrsonima sericea leaves are extensively used in folk medicine in Brazil against gastric disorders. This study investigated the chemical constituents of B. sericea leaf ethanolic extract (BSLE) and its potential gastroprotective activity, with its possible mechanism of the action using ethanol to induce gastric mucosal damage in mice. The phytochemical analysis was carried out to identify the active constituents present in the extract, and the HPLC analysis was performed for the identification of flavonoids. BSLE at oral doses of 125, 250 and 500 mg/kg markedly attenuated the ethanol-evoked gastric lesions by 53.2, 84.9 and 87.6 %, respectively. The BSLE (250 mg/kg) prevented the depletion of gastric mucus and gastric mucosal nonproteic-sulfhydryl groups,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antioxidant; Byrsonima sericea; Flavonoids; Gastroprotection; Mechanisms of action. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652012000100011 |
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| GARCIA,CHARLENE S.C.; MENTI,CAROLINE; LAMBERT,ANA PAULA F.; BARCELLOS,THIAGO; MOURA,SIDNEI; CALLONI,CAROLINE; BRANCO,CÁTIA S.; SALVADOR,MIRIAN; ROESCH-ELY,MARIANA; HENRIQUES,JOÃO A.P.. |
| ABSTRACT Salvia officinalis (Lamiaceae) has been used in south of Brazil as a diary homemade, in food condiment and tea-beverage used for the treatment of several disorders. The objective of this study was to characterize chemical compounds in the hydroalcoholic (ExtHS) and aqueous (ExtAS) extract from Salvia officinalis (L.) by gas chromatography-mass spectrometry (GC-MS) and by high-resolution electrospray ionization mass spectrometry (ESI-QTOF MS/MS), evaluate in vitro ability to scavenge the free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH•) and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS•+), catalase (CAT-like) and superoxide dismutase (SOD-like) activity, moreover cytotoxic by MTT assay, alterations on cell morphology by giemsa and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antioxidant; Apoptosis; Cancer; Chemical compounds; Salvia officinalis (L. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000100281 |
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| PINTO,MARIA E.A.; ARAÚJO,STHÉFANE G.; MORAIS,MARCELA I.; SÁ,NÍVEA P.; LIMA,CAROLINE M.; ROSA,CARLOS A.; SIQUEIRA,EZEQUIAS P.; JOHANN,SUSANA; LIMA,LUCIANA A.R.S.. |
| ABSTRACT Fatty acid methyl esters (FAMEs) were obtained from vegetable oils of soybean, corn and sunflower. The current study was focused on evaluating the antifungal activity of FAMEs mainly against Paracoccidioides spp., as well as testing the interaction of these compounds with commercial antifungal drugs and also their antioxidant potential. FAMEs presented small IC50 values (1.86-9.42 μg/mL). All three FAMEs tested showed antifungal activity against isolates of Paracoccidioides spp. with MIC values ranging from 15.6-500 µg/mL. Sunflower FAMEs exhibited antifungal activity that extended also to other genera, with an MIC of 15.6 μg/mL against Candida glabrata and C. krusei and 31.2 μg/mL against C. parapsilosis. FAMEs exhibited a synergetic effect with... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antifungal; Antioxidant; Fatty acid methyl esters; Vegetable oils. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000401671 |
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| SOUSA,WENDEL C. DE; T.S. PAZ,ANDRESSA; ROCHA,JAMIRA D.; CONCEIÇÃO,EDEMILSON C. DA; ALMEIDA,LUCIANE M. DE; CHEN,LEE C.; BORGES,LEONARDO L.; BAILÃO,ELISA F.L.C.. |
| ABSTRACT Costus spiralis is a Brazilian native plant used in popular medicine, but the safety of this therapeutic use needs investigation. So, the aim of this study was to evaluate the cytogenotoxic and antigenotoxic effects of C. spiralis leaves or stems aqueous extracts on Allium cepa root cells. Moreover, a phytochemical screening and an antioxidant and antifungal activities evaluation were performed. C. spiralis aqueous extracts presented cytotoxicity, but no mutagenicity was observed. When the antigenotoxicity was evaluated, C. spiralis leaves aqueous extract presented preventive and modulatory effects on A. cepa root cells, reducing the sodium azide cytogenotoxic effects. In contrast, C. spiralis stems aqueous extract enhanced the sodium azide... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Allium cepa test; Antioxidant; Medicinal plant; Secondary metabolites. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000401565 |
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| PEREIRA,JOQUEBEDE R.; QUEIROZ,RAPHAEL F.; SIQUEIRA,ERLÂNIA A. DE; BRASILEIRO-VIDAL,ANA CHRISTINA; SANT’ANA,ANTÔNIO E.G.; SILVA,DANIEL M.; AFFONSO,PAULO R.A. DE MELLO. |
| ABSTRACT Mansoa hirsuta (Bignoniaceae) is a native plant from caatinga in Brazilian semiarid. This plant has been locally used as antimicrobial and hypoglycemiant agents, but their action mechanisms and toxicity remain largely unknown. Therefore, we evaluated the composition and antioxidant, cytoprotective and hypoglycemiant effects of raw extract, fractions and compounds from leaves of M. hirsuta. The cytogenotoxic effects of ursolic and oleanolic acids, the main phytotherapic components of this plant, were assessed. The raw extract and fractions presented steroids, saponins, flavonols, flavanonols, flavanones, xanthones, phenols, tannins, anthocyanins, anthocyanidins and flavonoids. The ethyl acetate fraction inhibited efficiently the cascade of lipid... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antioxidant; Caatinga; Cytotoxicity; Hypoglycemiant; Phytochemistry.. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000100317 |
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| SARMA,CHAYANIKA; RASANE,PRASAD; KAUR,SAWINDER; SINGH,JYOTI; SINGH,JOGINDER; GAT,YOGESH; GARBA,UMAR; KAUR,DAMANPREET; DHAWAN,KAJAL. |
| Abstract Piper betle L., is an evergreen perennial creeper belonging to family Piperaceae and is known to possess numerous medicinal properties. Current study focuses on evaluating antioxidant and antimicrobial potential of betel leaf. For the present study, distilled water, hexane, acetone and ethanolic extracts of two varieties of betel leaves: Meetha paan and Banarasi paan were used. Biochemical tests such as proximate analysis (moisture, ash, protein, lipids, minerals viz., sodium and potassium), antioxidant activity tests (DPPH radical scavenging activity, total phenolics, ascorbic acid, reducing power) and antimicrobial test (antibacterial and antifungal susceptibility test) against four pathogens viz., B. subtilis, E. coli, A. niger and S.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Piper betle; Piperaceae; Antioxidant; Antimicrobial; Biochemical. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000703871 |
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| DEL-VECHIO-VIEIRA,GLAUCIEMAR; SANTOS,BRUNA C.S.; ALVES,MARIA SILVANA; ARAÚJO,AÍLSON L.A.; YAMAMOTO,CÉLIA H.; PINTO,MÍRIAM A.O.; KAPLAN,MARIA AUXILIADORA C.; SOUSA,ORLANDO V.. |
| ABSTRACT The present study was designed to investigate the antioxidant, antinociceptive and anti-inflammatory activities of the ethanol extract from Ageratum fastigiatum branches. Phytochemical screening and total phenol and flavonoid contents were determined. The antioxidant activity was assessed by 2,2-diphenyl-1-pycrilhydrazin (DPPH) and iron reducing power methods. The antinociceptive effect was evaluated using the acetic acid-induced writhing, formalin, hot plate and tail immersion assays; while the carrageenan-induced paw edema and pleurisy tests were performed to examine the anti-inflammatory activity against acute inflammation. The extract revealed the presence of flavonoids, tannins, coumarins, terpenes, sterols and saponins. Expressive levels of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ageratum fastigiatum; Analgesic; Anti-inflammatory; Antioxidant; Flavonoids; Total phenols. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000401471 |
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| SANTOS,TÁSSIA L.A. DOS; QUEIROZ,RAPHAEL F.; SAWAYA,ALEXANDRA C.H.F.; LOPEZ,BEGOÑA GIMENEZ-CASSINA; SOARES,MILENA B.P.; BEZERRA,DANIEL P.; RODRIGUES,ANA CAROLINA B.C.; PAULA,VANDERLÚCIA F. DE; WALDSCHMIDT,ANA MARIA. |
| ABSTRACT Geopropolis is a special type of propolis produced by stingless bees. Several pharmacological properties have been described for different types of geopropolis, but there have been no previous studies of the geopropolis from Melipona mondury. In this study, we investigated the antioxidant, antibacterial, and antiproliferative activities of M. mondury geopropolis, and determined its chemical profile. The antioxidant activity was determined using in vitro ABTS·+, ·DPPH, and β-carotene/linoleic acid co-oxidation methods. The antibacterial activity was determined using a microdilution method with Pseudomonas aeruginosa, Staphylococcus aureus, and methicillin-resistant S. aureus. The antiproliferative effect was determined in tumor cell lines using the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antibacterial; Antioxidant; Antiproliferative; Geopropolis; Melipona mondury. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000502247 |
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| FREITAS,EDNARDO R.; FERNANDES,DANILO R.; SOUZA,DAVYD H.; DANTAS,FRANCISCO D.T.; SANTOS,REBECA C.; OLIVEIRA,GILSON B.; CRUZ,CARLOS EDUARDO B.; BRAZ,NÁDIA M.; CÂMARA,LORENA F.; NASCIMENTO,GERMANO A.J.; WATANABE,PEDRO H.. |
| ABSTRACT The aim of this study was to evaluate the effect of Syzygium cumini leaves (SCL) in laying hens diets on productive performance, egg quality and lipid oxidation of yolk. A total of 108 Hysex White laying hens were distributed in a completely randomized design with three treatments and six replicates of six birds each. The treatments consisted of SCL inclusion at dietary levels of 0, 5 and 10 g/kg. There was no significant effect of SCL inclusion on feed intake, laying percentage, weight and egg mass, feed conversion ratio, Haugh units, specific gravity, percentage of yolk, albumen and egg shells and shell thickness. However, the inclusion of SCL significantly influenced the yolk color and yolk lipid oxidation measured by TBARS values. Yolk color... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antioxidant; Egg quality; Phytogenic additives; Yolk color. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000502479 |
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| LAHNECHE,AMINA M.; BOUCHEHAM,RATIBA; OZEN,TEVFIK; ALTUN,MUHAMMED; BOUBEKRI,NASSIMA; DEMIRTAS,IBRAHIM; BICHA,SABRINA; BENTAMENE,ALI; BENAYACHE,FADILA; BENAYACHE,SAMIR; ZAMA,DJAMILA. |
| Abstract: This study aimed to evaluate the in vitro antiproliferative and inhibition of oxidative DNA-damage activities of n-butanol (n-BuOH) extract of Centaurea sphaerocephala. The in vitro antioxidant activity of the ethyl acetate (EtOAc) and the n-BuOH extracts of this plant were also assayed. To investigate the antioxidant potential, extracts were tested for their capacity to scavenge 1,1-diphenyl-2-picrylhydrazyl (DPPH·) and to inhibit lipid peroxidation using the TBARs method. The contents of total phenolics and flavonoids were measured. Additionally, antiproliferative activity and DNA-damage inhibition of the n-BuOH extract was determined using XCELLigence RTCA instrument and photolyzing 46966 plasmid, respectively. The results exhibited that the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Centaurea sphaerocephala; Phenolics; Antioxidant; Lipid peroxidation; Antiproliferative; DNA-damaged inhibition. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000500619 |
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| Registros recuperados: 183 | |
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