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| Registros recuperados: 215 | |
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| Droguet, Mickael; Devauchelle, Nicole; Pennec, Jean-pierre; Quinn, Brian; Dorange, Germaine. |
| European Community regulations on chemicals promote alternative methods to test substances presenting potential risks for the environment. In the present work, cultured atrial cells isolated from oyster (Crassostrea gigas) were used as an experimental model to investigate the toxicity of tributyltin (TBT) after short-time exposure at concentrations representative of those that can be measured in seawater, marine sediments and/or bivalves bioaccumulating this pollutant. In vitro and in vivo assays produce values of the same order of magnitude for both animal/cell survival and heart/cardiomyocyte beating rate. The survival rate of whole animals decreased from 10(-6) M TBT after 3 days. For cultured cells, the viability, evaluated using 3-(4,... |
| Tipo: Text |
Palavras-chave: Oyster; Heart cells; Flow cytometry; Tributyltin; Toxicity; Antifouling. |
| Ano: 2012 |
URL: http://archimer.ifremer.fr/doc/00089/20032/17688.pdf |
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| Goutx, H; Berland, B; Leveau, M; Bertrand, J. |
| The effects of products resulting from petroleum biodegradation in continuous culture, have been studied on the growth of two marine algae. Sugars, lipids and amino acids are the main components resulting from petroleum degradation in the bacteria used medium. Their concentrations are respectively 600 mg.l super(-1), 46 mg.l super(-1) and 74.2 mu M.l super(-1). The algae growth is inhibited when products are enough concentrated; it is stimulated by low concentration. Among these products, lipids are more toxic than others. The two species show different sensitivity towards the used medium. Prorocentrum micans growth is more inhibited than that of Phaeodactylum tricornutum . |
| Tipo: Text |
Palavras-chave: Bacteria; Phytoplankton; Toxicity; Oil pollution; Crude oil; Biodegradation. |
| Ano: 1984 |
URL: http://archimer.ifremer.fr/doc/1984/acte-1017.pdf |
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| Stachowski Haberkorn, S; Quiniou, Francoise; Nedelec, M; Robert, Rene; Limon, G; De La Broise, D. |
| Effects of the herbicide Basamais (bentazon) and the fungicide Opus (epoxiconazole) on oyster spat (Crassostrea gigas) were assessed using in-situ microcosms in a field experiment lasting 13 days. Six-week-old hatchery spat (mean size 1.1 mm), previously collected on PVC plates, was immersed in glass bottles filled with 200 mu m filtered seawater. Bottles were maintained underwater at 6 m depth and their water content changed every other day. Growth, measured as shell area index increase, was 126 +/- 4% in the control bottles. While no growth differences were observed between control and individual pesticide treatments at 10 mu g l(-1), oysters treated with a mix of 10 mu g l(-1) Opus and 10 mu g l(-1) Basamais showed a 50% growth reduction compared with... |
| Tipo: Text |
Palavras-chave: Epoxiconazole; Bentazon; Pesticide; Toxicity; Oyster; Microcosm. |
| Ano: 2008 |
URL: http://archimer.ifremer.fr/doc/2008/publication-4134.pdf |
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| Coquille, Nathalie; Menard, Dominique; Rouxel, Julien; Dupraz, Valentin; Eon, Melissa; Pardon, Patrick; Budzinski, Helene; Morin, Soizic; Parlanti, Edith; Stachowski-haberkorn, Sabine. |
| Microalgae, which are the foundation of aquatic food webs, may be the indirect target of herbicides used for agricultural and urban applications. Microalgae also interact with other compounds from their environment, such as natural dissolved organic matter (DOM), which can itself interact with herbicides. This study aimed to evaluate the influence of natural DOM on the toxicity of three herbicides (diuron, irgarol and S-metolachlor), singly and in ternary mixtures, to two marine microalgae, Chaetoceros calcitrans and Tetraselmis suecica, in monospecific, non-axenic cultures. Effects on growth, photosynthetic efficiency (Ф’M) and relative lipid content were evaluated. The chemical environment (herbicide and nutrient concentrations, dissolved organic carbon... |
| Tipo: Text |
Palavras-chave: Microalgae; Herbicides; Natural dissolved organic matter; DOM; Toxicity; Interactions. |
| Ano: 2018 |
URL: https://archimer.ifremer.fr/doc/00428/53964/55113.pdf |
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| Bouilly, Karine; Mccombie, Helen; Leitao, Alexandra; Lapegue, Sylvie. |
| Widespread use of the herbicide atrazine has incited much research on its toxicity in aquatic systems, where it is routinely detected due to runoff from cultivated fields. Moreover, the determination of the genotoxic effect of such pollutants in the marine environment has become a major requirement for ecosystem protection. In the Pacific oyster, Crassostrea gigas, hypodiploid aneuploid cells have regularly been reported. There is a negative correlation between this phenomenon and growth, as well as evidence for a genetic basis. A positive relationship between atrazine and aneuploidy has previously been demonstrated in C. gigas adults and juveniles. To evaluate the persistence of this impact, our study examined the offspring of the same adult population... |
| Tipo: Text |
Palavras-chave: Aneuploidy; Crassostrea gigas; Atrazine; Toxicity; Pollutant persistence. |
| Ano: 2004 |
URL: http://archimer.ifremer.fr/doc/2004/publication-580.pdf |
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| Alzieu, Claude. |
| The necessity to combat oil slicks makes it necessary to assess the relative effectiveness and toxicity of dispersal agents used. This is usually done by using individual or groups of indicator organisms. The theory behind the various approaches is outlined, and some considerations are listed for the choice of technique. 2 organisms were chosen - the Portuguese oyster (Crassostrea), and the phytoplankton alga Phaeodactylum tricornutum Bohlin, on which if feeds - and the oyster closing reaction, and level of inhibition of growth under the influence of irritant products was measured. Methods are described, and the results shown for emulsifying, agglomerating and precipitating products. The results are discussed, and the mode of interference of the products... |
| Tipo: Text |
Palavras-chave: Choice of technique; Phytoplankton; Organisms; Toxicity; Oil spills; Pollution. |
| Ano: 1972 |
URL: http://archimer.ifremer.fr/doc/1972/publication-2073.pdf |
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| Chouteau, Mathieu; Dezeure, Jules; Sherratt, Thomas N.; Llaurens, Violaine; Joron, Mathieu. |
| Müllerian mimicry between chemically defended species arises from selection exerted by predators in which individuals benefit from higher survival when they share the same warning signal. However, despite sharing warning signals, co-mimetic species harbour a diversity of toxins at a range of different concentrations. This variation may affect the rate of predator avoidance learning and therefore the dynamics of mimicry. Here, to understand the nature of mimetic relationships in natural communities of butterflies and moths, we compared protection against predators induced by chemical defences of 13 lepidopteran species belonging to six mimicry complexes. Protection was estimated by quantifying the extent of avoidance learning, using domestic chicks, Gallus... |
| Tipo: Text |
Palavras-chave: Aposematism; Mullerian mimicry; Predator aversion; Quasi-Batesian mimicry; Toxicity. |
| Ano: 2019 |
URL: https://archimer.ifremer.fr/doc/00500/61197/67181.pdf |
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| Rodier, M; Longo, S; Henry, K; Ung, A; Lo-yat, Alain; Darius, Ht; Viallon, J; Beker, B; Delesalle, B; Chinain, M. |
| Pearl farming lagoons are economically important, yet poorly studied ecosystems in French Polynesia. This paper describes a study conducted in 2016 in Takaroa (Tuamotu Archipelago), an atoll recurrently affected by harmful algal bloom (HAB) events. The objectives were to gain insight into phytoplankton community composition, identify the main bloom-forming species and investigate their potential for toxicity. A mesocosm approach was used to assess the response of phytoplankton communities to 3 nutrient treatments: Conway with Si, Si-depleted f/2 and a commercial N-P fertilizer. In total, 87 morpho-species were described from Takaroa lagoon, with dinoflagellates as the most diverse group. Diatoms (Extubocellulus sp., Cylindrotheca closterium, Nitzschia... |
| Tipo: Text |
Palavras-chave: Phytoplankton; Taxonomy; Mesocosm; Bloom-forming species; Toxicity; French Polynesian lagoons. |
| Ano: 2019 |
URL: https://archimer.ifremer.fr/doc/00499/61059/64509.pdf |
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| Ben-gharbia, Hela; Yahia, Ons Kefi-daly; Amzil, Zouher; Chomerat, Nicolas; Abadie, Eric; Masseret, Estelle; Sibat, Manoella; Triki, Habiba Zmerli; Nouri, Habiba; Laabir, Mohamed. |
| armful benthic dinoflagellates, usually developing in tropical areas, are expanding to temperate ecosystems facing water warming. Reports on harmful benthic species are particularly scarce in the Southern Mediterranean Sea. For the first time, three thermophilic benthic dinoflagellates (Ostreopsis cf. ovata, Prorocentrum lima and Coolia monotis) were isolated from Bizerte Bay (Tunisia, Mediterranean) and monoclonal cultures established. The ribotyping confirmed the morphological identification of the three species. Maximum growth rates were 0.59 ± 0.08 d−1 for O. cf. ovata, 0.35 ± 0.01 d−1 for C. monotis and 0.33 ± 0.04 d−1 for P. lima. Toxin analyses revealed the presence of ovatoxin-a and ovatoxin-b in O. cf. ovata cells. Okadaic acid and... |
| Tipo: Text |
Palavras-chave: Ostreopsis cf. ovata; Prorocentrum lima; Coolia monotis; Southern Mediterranean Sea; Growth; Toxicity. |
| Ano: 2016 |
URL: https://archimer.ifremer.fr/doc/00355/46585/46393.pdf |
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| Alzieu, Claude; Heral, Maurice. |
| The toxic effect of trialkyltin compounds is used in antifouling paints to protect vessels against biofouling organisrns. Tributyltin oxide (TBTO) or fluoride (TBTS) leaches by diffusion from the paint layer into the seawater. Trialkyltin compounds in aqueous solutions are resistant to hydrolysis and biodegradation, but are rapidly converted into diakyl, monoalkyl and inorganic tin by UV irradiation. As inhibiting agents of the oxidative phosphorylation, organotin compounds are extremely dangerous for aquatic organisms such as molluscs. The following estimated toxicity levels for Crassostrea gigas oyster larvae have been put forward : at 100 µg.l(1) the fecondation is inhibited, at 10 µg.l1 the already of 20 % of the eggs is affected larval development... |
| Tipo: Text |
Palavras-chave: Toxicity; Fluoride; Tribultyltin oxide; Toxic effect; Oysters; Crassostrea gigas. |
| Ano: 1984 |
URL: http://archimer.ifremer.fr/doc/1984/publication-2931.pdf |
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| Medhioub, Walid; Gueguen, Marielle; Lassus, Patrick; Bardouil, Michele; Truquet, Philippe; Sibat, Manoella; Nejib, Medhioub; Philippe, Soudant; Mejdeddine, Kraiem; Amzil, Zouher. |
| In the Gulf of Gabes (Tunisia, Eastern Mediterranean sea), the grooved carpet shell Ruditapes decussatus has been seen to contain persistent levels of gymnodimine (GYM) for several years. The present experimental work represents the first attempt to assess detoxification kinetics of fast-acting toxins (FAT) in marine molluscs fed specific diets of non-toxic algae (Isochrysis galbana). To find an optimal detoxification method, two experiments were performed in which clams were first fed the toxic dinoflagellate Karenia selliformis to artificially contaminate them with GYM, thus simulating the effect of natural toxic episodes. As a second step, the same clams were fed a non-toxic algae, I. galbana. to speed up the detoxification process. Changes in toxin... |
| Tipo: Text |
Palavras-chave: Ruditapes decussates; Grooved carpet shell; Karenia selliformis; Gymnodimine; Toxicity; Detoxification. |
| Ano: 2010 |
URL: http://archimer.ifremer.fr/doc/2010/publication-7488.pdf |
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| Medhioub, Amel; Medhioub, Walid; Amzil, Zouher; Sibat, Manoella; Bardouil, Michele; Ben Neila, Idriss; Mezghani, Salah; Hamza, Asma; Lassus, Patrick. |
| Karenia selliformis strain GM94GAB was isolated in 1994 from the north of Sfax, Gabes gulf, Tunisia. This species, which produces gymnodimine (GYM) a cyclic imine, has since been responsible for chronic contamination of Tunisian clams. A study was made by culturing the microalgae oil enriched Gaillard f/2 medium. The influence of growing conditions oil toxin content was studied, examining the effects of (i) different culture Volumes (0.25 to 40 litre flasks), (ii) two temperature ranges (17-15 degrees C et 20-21 degrees C) and (iii) two salinities (36 and 44). Chemical analyses were made by mass spectrometry coupled with liquid chromatography (LC-MS/MS). Results showed that (i) the highest growth rate (0.34 +/- 0.14 div d(-1)) was obtained at 20 degrees C... |
| Tipo: Text |
Palavras-chave: Mouse bioassay; Gymnodimine; Toxicity; Growth; Karenia selliformis. |
| Ano: 2009 |
URL: http://archimer.ifremer.fr/doc/2009/publication-7383.pdf |
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| Bado Nilles, Anne. |
| The effects of PAHs, considered among the most toxic by the United States Environmental Protection Agency, were tested in vitro and in vivo on two commercial species of the Pertuis-Charentais (Charente-Maritime, France): sea bass, Dicentrarchus labrax, and the Pacific oyster, Crassostrea gigas. This study was carried out as part of the European project EROCIPS with the aim of finding new immunological biomarkers caused by occasional pollution by hydrocarbons. During in vitro experimentation, pollutants and immunological biomarkers were choosen. Thereafter, the in vitro exposures to the soluble fraction of Erika's heavy fuel oil and its fluxant, light cycle oil, began. These exposures enable the validation of the experimental system used, with, in... |
| Tipo: Text |
Palavras-chave: Biliary metabolites; Bioaccumulation; Toxicity; Immune défense; European sea bass; Pacific oyster; Métabolites biliaires; Bioaccumulation; Toxicité; Capacités de défense; Hydrocarbure; Bar commun; Huître creuse. |
| Ano: 2008 |
URL: http://archimer.ifremer.fr/doc/2008/these-7401.pdf |
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| Alzieu, Claude; Heral, Maurice; Thibaud, Yves; Dardignac, Marie-jose; Feuillet, Michèle. |
| Experiments in oyster-breeding areas where oyster Crassostrea gigas suffers from anomalies of calcification, show an obvious correlation between the importance of the malformation of shells and the vicinity of port areas where a great number of boats usually stay. Organotin compounds contained in antifouling paints, and more precisely Tributyltin fluoride (TBTF) induce, in experimental environment, similar anomalies to those observed in natural environment. The amounts of total tin in the tissues of oysters living in the vicinity of spots where organotin products are brought in, can reach high values, though they appear to decrease rapidly whereas the environmental contamination lessens. The authors suggest that results of organotin upon the mechanisms of... |
| Tipo: Text |
Palavras-chave: Crassostrea gigas; Pollution effects; Toxicity; Calcification; Fouling control; Paints. |
| Ano: 1981 |
URL: http://archimer.ifremer.fr/doc/1981/publication-1898.pdf |
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| Almansour,Mansour; Jarrar,Yazun; Jarrar,Bashir. |
| Sildenafil is widely used for the treatment of erectile dysfunction with few studies are available on the protective role of propolis against its reproductive toxicity. The present study aims to investigate the hormonal biochemical and histomorphometric alterations induced in the testicular tissues by sildenafil overdoses. Four groups of rabbits were exposed to sildenafil with or without propolis as follows: Group I received the formulated vehicle, Group II received sildenafil (3 mg/kg), Group III received propolis (50 mg/kg), Group IV received sildenafil plus propolis. Sildenafil lowered body weight gain, testosterone and follicular stimulating hormone concentration but increased testis index while luteinizing hormone was almost not affected. Moreover,... |
| Tipo: Journal article |
Palavras-chave: Propolis; Sildenafil; Testis; Histological alterations; Toxicity. |
| Ano: 2016 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000200020 |
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| Imosemi,I.O; Osinubi,A.A. |
| The role of methanolic leaf extracts of Calotropis procera in phenytoin-induced toxicity on histomorphometric variables in the postnatal developing cerebellum of Wistar rat was studied. Pregnant rats were treated orally with 50 mg/kg phenytoin in pre and post natal life and 300 mg/kg methanolic leaf extract of Calotropis procera 1 hour prior to phenytoin administration. 200 mg/kg vitamin C (standard antioxidant) was also administered orally 1 hour prior to phenytoin treatment. The control animals received water. Standard diet of rat pellets and water were provided ad libitum. At the end of the experiment, the offspring of days 1, 7, 14, 21, 28 and 50 post partum, five per group were sacrificed by cervical dislocation. The cerebellum of all groups were... |
| Tipo: Journal article |
Palavras-chave: Phenytoin; Toxicity; Cerebellar development; Calotropis procera. |
| Ano: 2011 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000200004 |
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| Teruel,M; García,V; Catalano,R. |
| The aim of this work was to evaluate the effect of albendazole sulphoxide (ABZSO), administered to Wistar rats during pregnancy on embryonic, foetal and placental parameters. A colpocytological control was performed daily and detection of spermatozoa in the vaginal smear was considered as day 0 of pregnancy. For the preimplantational study, ABZSO (10 mg/kg) was orally administered at day 2 of pregnancy; at day 4 the embryos were collected. For the postimplantational study, ABZSO (10 mg/kg) was orally administered by gavages at day 2, 6 or 10 of pregnancy (G2, G6 and G10 Groups respectively); the control group was administered the same volume of carboxymethylcellulose vehicle used to prepare the drug suspension. Fetuses were obtained from pregnant rats... |
| Tipo: Journal article |
Palavras-chave: Albendazole Sulphoxide; Gestation; Toxicity; Wistar Rats. |
| Ano: 2009 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000400030 |
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| Chattopadhyay,P; Pandey,A; Goyary,D; Chaurasia,A; Singh,L; Veer,V. |
| The toxicity of deoxynivalenol, both intravenously and orally, was investigated in male and female BALB/c mice. Technetium-99m (99m Tc)-labeled deoxynivalenol was administered to mice by tail vein injection and orally dosed. Distribution of labeled deoxynivalenol at 26 hours was monitored by gamma-scintigraphy. In the evaluated organs, the accumulation of radioactive deoxynivalenol was correlated with the amount of radioactivity. In addition, the toxicity of deoxynivalenol was measured by biochemical assays followed by histopathological findings. Kidney and hepatic marker enzymes were significantly increased in intravenously administered deoxynivalenol as compared to orally treated mice. Intravenously treated mice showed severe damage in liver and kidney... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Technetium-99m (99mTc); Deoxynivalenol; Biodistribution; Toxicity; Histopathology. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992012000300002 |
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| Registros recuperados: 215 | |
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