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| Registros recuperados: 100 | |
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| Arshad,Wajeeha; Khan,Haji Muhammad Shoaib; Akhtar,Naveed; Mohammad,Imran Shair. |
| Currently, the use of natural compounds obtained from plants tremendously increased due to their promising therapeutic properties. The aim of this study was to formulate a stable emulgel formulation loaded with Cinnamomum tamala (CT) extract. The antioxidant activity of plant extract was determined by DPPH inhibition assay. The extract was successfully loaded into an emulgels using different concentrations of carbopol-940, liquid paraffin, emulsifying agents and preservatives. Preliminary stability study was performed of 17 CT emulgel formulations at accelerated temperature of 50 °C for 2-months. Organoleptic evaluation, centrifugation, globule size, pH, electrical conductivity and rheological studies were performed for a period of 90-days at different... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cinnamomum tomala; Antioxidants; Emulgel; Physicak stability; Non-Newtonian; Pseudo-plasticity. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100553 |
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| Vellosa,José Carlos Rebuglio; Khalil,Najeh Maissar; Gutierres,Vânia Ortega; Santos,Vânia Aparecida de Freitas Formenton Macedo dos; Furlan,Maysa; Brunetti,Iguatemy Lourenço; Oliveira,Olga Maria Mascarenhas de Faria. |
| Reactive oxygen species (ROS) and free radical species have been implicated in initiating or accompanying many diseases in living organisms; there is thus, a continual need for antioxidants molecules to inactivate ROS/free radicals. Many studies of plants crude extracts have demonstrated free-radical scavenging and antioxidant action. Salacia species have long been used, in several countries, as traditional medicines against certain diseases and for their anti-inflammatory properties. In this study, Salacia campestris Walp (Hippocrateaceae) root bark ethanol extract (ScEtOH) was assessed for its ability to scavenge free radicals and reactive oxygen species; the results were expressed as percentage inhibition of the active species. ScEtOH was efficient... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Salacia campestris Walp/antioxidant properties; Hippocrateaceae; Myeloperoxidase; Reactive oxygen species; Antioxidants; Free radicals. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000100012 |
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| Galvão,Suzana Maria Pereira; Mendes,Fúlvio Rieli; Oliveira,Maria Gabriela Menezes de; Mattei,Rita; Mello,João Carlos Palazzo de; Roman Júnior,Walter Antonio; Carlini,Elisaldo de Araújo. |
| Few data exists about the pharmacological properties of Heteropterys aphrodisiaca O. Mach. (Malpighiaceae), which is native to the scrubland regions of Brazil. The present study investigated the effects of oral treatment with H. aphrodisiaca extract (BST0298) on the learning and memory of young (3-6 months) and aged (21-23 months) rats, and compared the in vitro antioxidant activity of three lots collected in different years. An improvement in the number of sessions to learn the task was observed in the left/right discrimination test in aged rats treated for 45 days with 25 mg/kg (7.0 ± 0.5; p=0.005) or 50 mg/kg (7.6 ± 0.6; p=0.012) compared with control old rats (11.0 ± 1.6). On the other hand, pre-treatment did not improve the performance of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Heteropterys aphrodisiaca O. Mach/pharmacognosy; Heteropterys aphrodisiaca O. Mach/antioxidant activity; Malpighiaceae/pharmacognosy; Antioxidants; Flavonoids; Plant extract. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000400020 |
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| Farias,Carine Coneglian de; Bonifácio,Kamila Landucci; Matsumoto,Andressa Keiko; Higachi,Luciana; Casagrande,Rúbia; Moreira,Estefânia Gastaldello; Barbosa,Décio Sabbatini. |
| Parkinson's disease (PD) is characterized by progressive degeneration of dopaminergic neurons in the substantia nigra pars compacta. Furthermore, oxidative stress plays a role in PD, causing or contributing to the neurodegenerative process. Currently PD has only symptomatic treatment and still nothing can be done to stop the degenerative process of the disease. This study aimed to comparatively evaluate the antioxidant capacity of pramipexole, selegeline and amantadine in different in vitrostudies and to offer possible explanations on the molecular antioxidant mechanisms of these drugs. In vitro, the antioxidant capacity of the drugs was assessed by the ability of antiparkinsonian drugs to decrease or scavenge ROS in the neutrophil respiratory burst,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Parkinson´s disease; Oxidative stress; Antiparkinsonian drugs/in vitrostudies; Antioxidants. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000400819 |
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| Costa-Mugica,Ariana; Batista- Gonzalez,Ana Elsa; Mondejar,Diadelis; Soto-López,Yosdel; Brito-Navarro,Victor; Vázquez,Ana Maria; Brömme,Dieter; Zaldívar-Muñoz,Claudina; Vidal-Novoa,Alexis; Silva,Ana Mara de Oliveira e; Mancini-Filho,Jorge. |
| LDL oxidation and oxidative stress are closely related to atherosclerosis. Therefore, natural antioxidants have been studied as promising candidates. In the present study, the LDL oxidation inhibition activity of bioactive compounds from Halimeda incrassata seaweed. associated to antioxidant capacity, was evaluated in vitro. Experimental work was conducted with lyophilized aqueous extract and phenolic-rich fractions of the seaweed and their effect on LDL oxidation was evaluated using heparin-precipitated LDL (hep-LDL) with exposure to Cu2+ ions and AAPH as the free radical generator. H. incrassata had a protective effect for hep-LDL in both systems and the presence of phenolic compounds contributed to the activity where phenolic-rich fractions showed... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Halimeda incrassata/antioxidant properties; Antioxidants; Polyphenols; Lipoproteins/oxidation inhibition. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502012000100004 |
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| Bramorski,Adriana; Cherem,Adriana da Rosa; Marmentini,Chaiana Paula; Torresani,Joseane; Mezadri,Tatiana; Costa,Andréa de Almeida Silva. |
| The plant Morinda citrifolia L. (noni) has been the focus of many recent studies due to its potential effects on treatment and prevention of several diseases. However, there are few in vivo and in vitro studies concerning its composition and antioxidant capacity. The aim of the present study was to determine the total polyphenol content (TPC) and antioxidant capacity of a juice commercialized as noni juice, but containing grape, blueberry and noni fruits. Commercial noni juice was compared against its separate constituents of blueberry and grape juice. Folin-Ciocalteu and DPPH methods were used to determine the concentration of total polyphenol content and antioxidant activity, respectively. Commercial noni juice presented higher values of TPC (91.90 mg... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Noni juice/antioxidant activity; Morinda citrifolia L.; Total polyphenols/determination; Antioxidants. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000400006 |
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| Jordao Júnior,Alceu Afonso; Domenici,Fernanda Aparecida; Lataro,Renata Cristina; Portari,Guilherme Vannucchi; Vannucchi,Helio. |
| Changes in the metabolism of methionine can cause hyperhomocysteinemia, inducing a triad of atherosclerosis, hypertension, and increased oxidative stress. The generation of free radicals and oxidative damage to DNA is important in the liver damage caused by ethanol. In this study, the effect of methionine overload associated or otherwise with acute administration of ethanol on homocysteine values, damage to DNA, lipoperoxidation and vitamin E was evaluated. Thirty rats were divided into 3 groups: Group Ethanol 24 hours (EG24), Group Methionine 24 hours (MG24), and Group Methionine and Ethanol 24 hours (MEG24). TBARS, vitamin E, GS and, homocysteine values were determined and the Comet assay was carried out. Increased GSH, vitamin E and homocysteine levels... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Methionine; Homocysteine; Free Radicals; Antioxidants; Ethanol/induced damage. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000400014 |
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| Trang,Do Hoang Thu; Son,Hoang Le; Trung,Phung Van. |
| ABSTRACT Antioxidants from natural sources hold high values regarding their indispensible roles in the development of nutraceuticals, pharmaceuticals and cosmetic products. Oroxylum indicum L. is a common medicinal plant with a wide range of therapeutic properties, including a notable antioxidant potency that was reported, yet has not been subjected to more detailed studies. The present study evaluated the potency of Oroxylum indicum methanol stem bark extract, along with its hexane, ethyl acetate, methanol fractions, three flavones including baicalein, oroxylin A and chrysin using DPPH assay. In terms of IC50 values, the crude extract (65,48 μg/mL) exhibited moderate inhibitory activity which was as half potent as that of its ethyl acetate fraction (32,94... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Oroxylum indicum; Flavones; Methanol/extract; DPPH assay; Antioxidants; Inhibitory Concentration 50; Bignoniaceae.. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000100619 |
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| Cao,Yu; Hao,Chuan-ji; Wang,Chen-jing; Li,Peng-li; Wang,Le-xin; Guan,Hua-shi; Li,Huan-ting. |
| The urine excretion of L-carnitine (LC), acetyl-L-carnitine (ALC) and propionyl-Lcarnitine (PLC) and their relations with the antioxidant activities are presently unknown. Liquid L-carnitine (2.0 g) was administered orally as a single dose in 12 healthy subjects. Urine concentrations of LC, ALC and PLC were detected by HPLC. Superoxide dismutase (SOD), total antioxidative capacity (T-AOC), malondialdehyde (MDA) and nitrogen monoxidum (NO) activities were measured by spectrophotometric methods. The 0~2 h, 2~4 h, 4~8 h, 8~12 h, 12~24 h excretion of LC was 53.13±31.36 µmol, 166.93±76.87 µmol, 219.92±76.30 µmol, 100.48±23.89 µmol, 72.07±25.77 µmol, respectively. The excretion of ALC was 29.70±14.43 µmol, 80.59±32.70 µmol, 109.85±49.21 µmol, 58.65±18.55 µmol,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: L-carnitine/antioxidant activity; Acetyl-L-carnitine/antioxidant activity; Propionyl-Lcarnitine/antioxidant activity; Antioxidants; Urine excretion/analysis. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000100020 |
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| Panda,S.K.; Choudhury,S.. |
| The article presents an overview of the mechanism of chromium stress in plants. Chromium is known to be a toxic metal that can cause severe damage to plants and animals. Chromium-induced oxidative stress involves induction of lipid peroxidation in plants that causes severe damage to cell membranes. Oxidative stress induced by chromium initiates the degradation of photosynthetic pigments causing decline in growth. High chromium concentration can disturb the chloroplast ultrastructure thereby disturbing the photosynthetic process. Like copper and iron, chromium is also a redox metal and its redox behaviour exceeds that of other metals like Co, Fe, Zn, Ni, etc. The redox behaviour can thus be attributed to the direct involvement of chromium in inducing... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antioxidants; Chromium; Fenton reactions; Metallothioneins; Oxidative stress. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-04202005000100008 |
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| Chakraborty,Usha; Pradhan,Bhumika. |
| Five varieties of wheat (Triticum aestivum L.) - KW, UP 2752, PBW 343, SO and LV - were subjected to water stress and sampling was done on the 3rd, 6th and 9th day of stress. RWC decline in KW, UP 2752 and PBW 343 (36.65, 42.34 and 40.75% respectively) was comparatively lesser than in LV and SO (52.93 and 52.67% respectively). In all varieties tested, three antioxidant enzymes (POX, APOX and GR) showed an initial increase. The activity of POX and GR increased with the increase in the duration of stress in KW, UP 2752 and PBW 343, while the activity of APOX declined. However, CAT and SOD showed an initial increase in these varieties, whereas it declined in SO and LV with increase in the period of stress. Accumulation of H2O2 declined during prolonged water... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antioxidants; Carotenoids; Drought; Lipid peroxidation. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-04202012000200005 |
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| Moggia,Claudia; Hernández,Omar; Pereira,Marcia; A. Lobos,Gustavo; Yuri,José Antonio. |
| A study was carried out to determine the effects of two cooling systems and the application of 1-methylcyclopropene (1-MCP, SmartFreshTM) on the incidence of superficial scald in apples (Malus domestica Borkh.) cv. Granny Smith. Fruit were collected from a commercial orchard (Colbún, Maule Region, Chile) during 2004-2005 season. A completely randomized design was used in a 2 x 2 factorial arrangement, using cooling systems (normal and step-wise cooling) and application of 1-MCP (0 and 625 nL L-1 i.a.) as the main factors. Fruit from normal cooling were kept at 0 °C throughout the storage period (180 days). Step-wise cooling consisted of storing the fruit at 10 °C for 10 days; 4 °C for the next 20 days and 0 °C for the remaining 150 days. Every month,... |
| Tipo: Journal article |
Palavras-chave: Conjugated trienes; Antioxidants; -farnesene; 1-methylcyclopropene; Physiological disorder; Ethylene. |
| Ano: 2009 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-58392009000300011 |
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| Campos-Vargas,Reinaldo; Defilippi,Bruno G; Romero Q,Paula; Valdés G,Héctor; Robledo M,Paula; Prieto E,Humberto. |
| Browning development is the most important factor limiting the quality of fresh-cut cherimoya (Annona cherimola Mill.). However, there is little information available about its causes and methods of control. The effectiveness of L-cysteine (0.125, 0.25 and 0.5%) in fresh-cut cherimoya harvested on two occasions (October and November) and stored for 6 and 12 days at 0 °C was studied. In order to understand the biological basis of browning, polyphenol oxidase (PPO) enzyme activity and total phenolic content in fresh-cut pieces were measured. Quality measurements and sensory analysis indicated that 0.5% L-cysteine was somewhat effective in reducing browning development, without affecting other quality attributes. In terms of physiological parameters, PPO... |
| Tipo: Journal article |
Palavras-chave: Antioxidants; Polyphenol oxidase; Phenolics; Sensorial evaluation. |
| Ano: 2008 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-58392008000300001 |
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| Mariangel,Emilia; Reyes-Diaz,Marjorie; Lobos,Walter; Bensch,Emma; Schalchli,Heidi; Ibarra,Pamela. |
| The antioxidant capacity (AC), total anthocyanins (TA) and total phenols (TP) of calafate fruit from four locations in southern Chile (El Blanco, Lonquimay, Mañihuales and Temuco) were determined using both the free radical 2.2-diphenyl-1-picrylhydrazyl (DPPH) method and the linoleic acid oxidation inhibition method as well as the pH-differential and Folin-Ciocalteu methods. Phenolic compounds were also identified using HPLC-DAD (High Performance Liquid Chromatography-Diode-Array Detection). The results showed that TP varied significantly according to the location. Mañihuales was noteworthy, with 34.9 mg of GAE g-1 dried fruit. The measured AC level depended on the methodology used, varying significantly between locations according to the DPPH results.... |
| Tipo: Journal article |
Palavras-chave: Antioxidants; Antioxidant capacity; Berberis; Flavonoids; Phenolic acids; Total phenols. |
| Ano: 2013 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-16202013000100014 |
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| Kobus-Cisowska,Joanna; Szczepaniak,Oskar; Szymanowska-Powałowska,Daria; Piechocka,Justyna; Szulc,Piotr; Dziedziński,Marcin. |
| ABSTRACT: Extraction conditions are an important factor in the process of obtaining bioactive compounds from plant matrix. These compounds differ structurally. Structures of phyto-compounds and their interactions with other food ingredient are not fully known, while these two aspects should play a significant role in extrahents choice and determination of extraction process conditions. Mulberry (Morus alba) is a plant growing in Asia, which fruits are rich in bioactive ingredients and high anti-oxidative potential. In our study we analyzed mulberry fruits extracts differing in the extra hent applied: acetone, methanol, ethanol and water. All tested extracts possessed rich polyphenolic composition and radical scavenging ability. The significant differences... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Morus alba; Antioxidants; Phenolic acids; Flavonoids. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782020000100751 |
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| Registros recuperados: 100 | |
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