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| Registros recuperados: 134 | |
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| Mariotti,Kristiane de Cássia; Schmitt,Gabriela Cristina; Barreto,Fabiano; Fortunato,Rodrigo E.; Singer,Rodrigo B.; Dallegrave,Eliane; Leal,Mirna Bainy; Limberger,Renata Pereira. |
| Gunnera perpensa (Gunneraceae) is an African plant widely used in traditional medicine. This species is known for its activity involving the female reproductive system, such as inducing or increasing labor, treating female infertility, expelling the placenta and/or preventing post-partum hemorrhage. These properties are probably due to (z)-venusol, a majoritary compound, and its action in conjunction with substances in the whole extract and other natural products. In southern Brazil, a native species Gunnera manicata L. that also belongs to Gunneraceae can be found. In spite of the traditional use of G. perpensa, there is no pharmacological and phytochemical information regarding the South American Gunnera species. Therefore, the aim of this study was to... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Gunnera manicata L./pharmacognosy; Gunneraceae/pharmacognosy; Medicinal plants; Uterotrophic assay/experimental study. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000300018 |
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| Cheng,Zhongzhe; Xie,Ming; Zhang,Wenjie; Cheng,Lan; Du,Yang; Wang,Yunjiao; Ying,Xixiang; Kang,Tingguo. |
| The objective of the present study was to develop a simple and selective HPLC method for the simultaneous determination of hesperidin (HP), caffeic acid (CA), ferulic acid (FA) and p-coumaric acid (p-CA) in rat plasma after intravenous administration of Portulaca oleracea L. extract (POE). With the hyperoside as the internal standard, the sample pretreatment procedure involved simple single-step extraction with methanol of 0.2 mL plasma. The mobile phase consisted of methanol-acetonitrile-tetrahydrofuran-0.5% glacial acetic acid (5:3:18:74, v/v/v/v). The calibration curves were linear over the range of 0.1-25 µg mL-1, 0.1-25 µg mL-1, 0.1-25 µg mL-1and 0.015-3 µg mL-1 for HP, CA, FA and p-CA, respectively. The method developed was suitable for the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Portulaca oleracea L./pharmacognosy; High Performance Liquid Chromatography/rat plasma; Vegetal extract/pharmacokinetic study; Medicinal plants. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502012000100018 |
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| Sousa,Sandra Alves de; Pascoa,Henrique; Conceição,Edemilson Cardoso da; Alves,Suzana Ferreira; Diniz,Danielle Guimarães Almeida; Paula,José Realino de; Bara,Maria Teresa Freitas. |
| "Guaraná" (Paullinia cupana) is used as a physical activity enhancer and stimulator due to its methylxanthines and condensed tannins. The aim of this work was to evaluate the dissolution behavior of five herbal medicines in the form of capsules and tablets containing guaraná. Assay and dissolution methods were validated and results obtained allowed simultaneous marker quantification with precision, accuracy, selectivity and robustness. Findings showed that 100% of the herbal medicinal products analyzed did not provide satisfactory results concerning the presence of four markers, 60% had three markers (caffeine, catechin and epicatechin), while 40% had only caffeine at tested dosage forms. In addition, after 30 minutes, only capsule A showed at least 80% of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Herbal medicines/quality control; Herbal medicines/dissolution behavior; Medicinal plants; Guaraná/pharmacognosy; Paullinia cupana/pharmacognosy. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000200008 |
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| Ferreira,Magda Rhayanny Assunção; Santiago,Rosilene Rodrigues; Silva-Rocha,Walicyranison Plínio; Souza,Luanda Barbara Ferreira Canário de; Faria,Maria Graciela Icher; Mello,João Carlos Palazzo de; Langassner,Silvana Maria Zucolotto; Chaves,Guilherme Maranhão; Milan,Eveline Pipolo; Svidzinski,Terezinha Inez Estivalet; Soares,Luiz Alberto Lira. |
| The aim of this study was evaluate the in vitro antifungal activity of crude extracts from Eugenia uniflora, Libidibia ferrea and Psidium guajava. The extracts were obtained by turbo-extraction using water (AQ) or acetone-water (AC-W) (7:3, v/v) as solvents and lyophilized to obtain the crude extracts (CE). The CE were characterized by UV-Vis, TLC and HPLC. The activity of CEs was investigated against clinical isolates of Candida spp. and the Minimum Inhibitory Concentration (MIC), MIC50 and MIC90 were determinated. The analysis by TLC showed that all CEs presented polyphenols (flavonoids and tannins). The CEs from E. uniflora showed higher amount of polyphenols (30.35 ± 2.15%, AC-W) and the HPLC analysis revealed the tannins in all extracts. The CEs of E.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Medicinal plants; Herbal extracts; Polyphenols; Candida isolates; Oral candidiasis. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100608 |
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| Cansian,Fernanda Colombi; Merino,Francis José Zortéa; Dias,Josiane de Fátima Gaspari; Zanin,Sandra Maria Warumby; Miguel,Obdulio Gomes; Miguel,Marilis Dallarmi. |
| Species from the Bignoniaceae Family, including the genus Tynanthus, are very prevalent in the tropical Americas, with specimens found in a large part of the Brazilian territory. These plants are commonly used in traditional medicine for several purposes, and some studies have described their chemical structure, in addition to other reports related to some species from this genus. This review aimed to gather information from published works concerning species of the genus Tynanthus, as well as to detect flaws in research related to these plants, which may have great biological and pharmaceutical importance. Also, this review points out some common chemical characteristics of these species, providing information that may help new researchers to improve... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Tynanthus/pharmacognosy; Tynanthus/phytochemistry; Tynanthus/biological activity; Bignoniaceae/pharmacognosy; Bignoniaceae/phytochemistry; Medicinal plants. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000300515 |
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| Pascoa,Henrique; Diniz,Danielle Guimarães Almeida; Florentino,Iziara Ferreira; Costa,Elson Alves; Bara,Maria Teresa Freitas. |
| This article reports the development of a pharmaceutical product containing vegetable actives from a Brazilian medicinal plant. The possibility of forming a microemulsion using Pterodon emarginatus ("sucupira") oil was evaluated and the anti-inflammatory potential of this microemulsion was also examined. A formulation was developed using P. emarginatus oil, a mixture of ethoxylated Castor Oil (Ultramone(r) R-540/propylene glycol 2:1) (surfactant/cosurfactant) and distilled water at a ratio of 10:15:75, respectively. The microemulsion which was selected was then subjected to the preliminary stability test and analyzed in terms of average diameter of droplets, pH, zeta potential, and polydispersity index, on the 1st, 7th, 15th, and 30th days after... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Pterodon emarginatus; Pterodon emarginatus; Medicinal plants; Microemulsion; Phytomedicine; Pharmaceutical technology. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000100117 |
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| Pereira,Flávia Liparini; Fernandes,José Martins; Leite,João Paulo Viana. |
| Ethnopharmacological studies are important for documenting and protecting cultural and traditional knowledge associated with the medical use of biodiversity. In this paper, we present a survey on medicinal plants used by locals in a community of Nova Viçosa, Viçosa, MG, Brazil, as a strategy to select medicinal plants for a phytotherapy-based local healthcare program. Eleven knowledgeable local informants were chosen by snowball sampling and interviewed about the use of medicinal plants. Plant samples were collected, herborised and then identified using traditional techniques and specialised literature. We sampled 107 medicinal plant species belonging to 86 genera and 39 families, predominantly Asteraceae with 16 species. Costus spicatus (Jacq.) Sw, M.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ethnopharmacology; Medicinal plants; Phytotherapy. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502012000200014 |
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| Paula,Isabela Moreira Baumgratz de; Moraes,Flávia Costa; Souza,Orlando Vieira de; Yamamoto,Célia Hitomi. |
| Rosmarinus officinalis, which belongs to the Lamiaceaefamily, is a species of medicinal flora with therapeutic properties. In order to exploit the benefits of these properties, a mouthwash formulation was developed, with careful selection of raw materials to meet pharmacotechnical requirements. Extracts of the plant were incorporated into a mouthwash, which was shown to have inhibitory action in vitro against the micro-organisms commonly found in periodontics. Controls for assessing the quality of the drugs were carried out, quantifying phenols and flavonoids as chemical markers. Mouthwash solutions were formulated containing 0.1, 5 and 10% ethanol extract of R. officinalis; and 0.05, 5 and 10% of the hexane fraction of R. officinalis. In order to evaluate... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rosmarinus officinalis/pharmacognosy; Rosmarinus officinalis/Anti-microbial activity; Mouthwash; Periodontics/use of mouthwash; Medicinal plants. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000400851 |
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| Bonfanti,Gabriela; Bitencourt,Paula Eliete Rodrigues; Bona,Karine Santos De; Peroza,Luis Ricardo; Cargnelutti,Lariane Oliveira; Borges,Raphaela Maleski; Pigatto,Aline Grohe Schirmer; Fachinetto,Roselei; Boligon,Aline Augusti; Athayde,Margareth Linde; Gonçalves,Thissiane de Lima; Moretto,Maria Beatriz. |
| ABSTRACT Solanum guaraniticum is a medicinal plant traditionally used to treat gastric and liver diseases. However, there is no documented evidence corroborating its safety. The present study evaluated the potential toxicity of S. guaraniticum leaf extract after acute administration in rats. Single doses of the extract (1.250, 2.500, and 5.000 mg/kg) were administered by gavage, and the rats were then monitored for 48 h and/or 14 days. Mortality, acute signs of toxicity, and general activity in the open field test were assessed as well as hematological and biochemical parameters, enzymatic activity (δ-aminolevulinate dehydratase and acetylcholinesterase), and oxidative stress parameters (lipid peroxidation level, non-protein thiol content, tissue catalase... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Solanum guaraniticum/leaf extract/toxicity; Solanum guaraniticum/phytochemistry; Medicinal plants; Solanaceae. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502016000100006 |
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| Baratto,Leopoldo Clemente; Duarte,Márcia do Rocio; Santos,Cid Aimbiré de Moraes. |
| Rauvolfia sellowii Müll. Arg. (Apocynaceae), a Brazilian native tree rich in indole alkaloids, is known as "pau-pra-tudo" and popularly used as hypocholesterolemic, hypoglycemic and antihypertensive. The aim of this work was to study the anatomy of the young stems and stem barks of this medicinal plant, in order to contribute to the identification of the species as a drug. The plant material was fixed and prepared according to standard microtechniques. The young stems have remaining epidermis, but a suberified peridermis is evident. The phellogen is located in the cortical region, forming suber externally. Underneath the phellogen, lies the phelloderm and collenchymatic region. In the cortex, there are numerous laticifers and some fibers. There is an... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rauvolfia sellowii/pharmacognosy; Apocynaceae/pharmacognosy; Medicinal plants; Vegetal anatomy; Internal phloem; Laticiferous ducts; Calcium oxalate crystals. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000300020 |
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| Cardoso,Claudia Andréa Lima; Coelho,Roberta Gomes; Honda,Neli Kika; Pott,Arnildo; Pavan,Fernando Rogério; Leite,Clarice Queico Fujimura. |
| Serjania erecta Radlk.(Sapindaceae) is a medicinal plant traditionally used in Brazil. We assayed the ethanolic extract of leaves and roots against seven microorganisms. The REMA (Resazurin Microtiter Assay) assay was used to measure the biological activity in vitro against Mycobacterium tuberculosis and our results showed moderate activity of the ethanolic extract. On the other hand S. aureus, P. aeruginosa, S. setubal, C. albicans, S. cerevisiae and E. coli revealed that the leaves and roots of S. erecta inhibited the growth of all microorganisms. The ethanolic extracts of leaves and roots showed low values of antioxidant activities. The ethanolic extracts of leaves and roots were analyzed by chromatographic and spectrometric methods. (-)-Epicatechin,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Serjania erecta Radlk/pharmacognosy; Serjania erecta Radlk/ethanolic extract; Serjania erecta Radlk/antioxidant activity; Serjania erecta Radlk/ethanolic extract; Serjania erecta Radlk/antimicrobial activity; Sapindaceae/pharmacognosy; Cipó-cinco-folhas/pharmacognosy; Flavonoids; Medicinal plants. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000400017 |
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| Hansen,Daiane; Haraguchi,Mitsue; Alonso,Antonio. |
| The plant of the genus Pterodon (Fabaceae, Leguminosae), commonly known as 'sucupira' or 'faveira', are disseminated throughout the central region of Brazil and has frequently been used in popular medicine for its anti-rheumatic, analgesic, and anti-inflammatory properties. In recent years, interest in these plants has increased considerably. The biological effects of different phytoextracts and pure metabolites have been investigated in several experimental models in vivo and in vitro. The literature describes flavonoids, triterpene and steroids, while one paper presented studies with proteins isolated from the genus. This review provides an overview of phytochemical and pharmacological research in Pterodon, showing the main chemical compounds studied to... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Sucupira; Pterodon/phytochemistry; Pterodon/pharmacognosy; Diterpenes/biological activity; Isoflavones/biological activity; Medicinal plants. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000400002 |
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| Oliveira Filho,Claudio Costa; Kampke,Edgar Hell; Vargas,Thais Souza; Salustriano,Nathacha Andrade; Scherer,Rodrigo; Fronza,Marcio; Campagnaro,Bianca Prandi. |
| ABSTRACT The objective was to investigate the total saponin and protodioscin concentrations and the cytotoxicity in vitro, of five samples of the plant Tribulus terrestris, commercially available in the metropolitan region of Vitória - Espirito Santo, Brazil, and to compare them with the aqueous extract of the plant. The chromatographic profile and quantification of protodioscin in commercial samples and plant extract were evaluated by LC-MS/MS. The percentage of total saponins were determined by the colorimetric method. Extracts and protodioscin cytotoxicity were analyzed by the MTT assay in three cell lineages: fibroblasts (L929), ovarian cancer (Ovcar3) and murine hepatoma (Hepa1c1c7). All extracts displayed high levels of total saponins (207.2 to 780.3... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Tribulus terrestres/saponin/protodioscin/concentrations; Medicinal plants; Cytotoxicity/in vitro. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000400622 |
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| Prichoa,Franciele Carla; Roman,Silvane Souza; Manfredini,Vanusa. |
| The use of plant species is emerging as an important alternative in the treatment of injuries. Therefore, the extract of Sonchus oleraceus 10% was employed in the repair of skin lesions. A total of 36 male Wistar rats were subjected to a punch injury and divided into three groups: a negative control, receiving no treatment, a positive control, treated with Dersani, and the experimental group treated with the extract. The injury was assessed macroscopically and microscopically. Morphometric data was collected at the 3rd, 5th and 7th postoperative day, and the experimental group showed greater changes in shrinkage of the lesion compared to control groups. On the 3rd postoperative day, the injury in the experimental group showed less necrotic tissue, lower... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Sonchus oleraceus/pharmacognosy; Skin lesions/treatment; Skin lesions/experimental study; Wound healing/experimental study; Medicinal plants. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000300019 |
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| Duarte,Márcia do Rocio; Silva,Ariane Gonçalves. |
| Gymnanthemum amygdalinum (Delile) Sch.Bip. ex Walp. (Asteraceae), better known by its former name Vernonia amygdalina Delile, is a small shrub used in folk medicine as an antipyretic, laxative, antimalarial and anthelmintic. Studies have demonstrated that different vegetal extracts possess antioxidant, antimicrobial and antiparasitic activities. Among the bioactive metabolites, there are sesquiterpene lactones, saponins, polyphenols and flavonoids. This study investigated the leaf and stem microscopic characters of G. amygdalinum, aiming to expand the knowledge on this medicinal species and indicate anatomical structures. Plant material was fixed and sectioned by freehand and using a microtome. The sections were either stained or underwent standard... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Gymnanthemum amygdalinum/pharmacognosy; Gymnanthemum amygdalinum/microscopic characterization; Vernonia amygdalina/pharmacognosy; Vernonia amygdalina/microscopic characterization; Asteraceae/pharmacognosy; Medicinal plants. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000400011 |
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| Ravishankar,Kakaraparthy; Kiranmayi,Garlanka Venkata Naga; Prasad,Yejella Rajendra; Devi,Lankadi. |
| Generally, Plants have immense potential in the wounds management and treatment.In Chinese herbology, Hibiscus plant is a potent herb and have a good medicinal values but not scientifically approached. The present study aims to investigate the wound healing and antimicrobial activity of ethanolic extract of Hibiscus hirtus Linn.(HH). Wound healing activity was carried out by excision, incision and burn wound models. Antimicrobial activity was determined by cup plate method. Healing rate was assessed from the rate of wound contraction, epithelialization rate, tensile strength, hexosamine and hydroxyproline content. From the obtained results, it was indicated that the wound contraction and increased tensile strength of Hibiscus hirtus extract exhibits potent... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hibiscus hirtus/wound healing activity/antimicrobial activity; Medicinal plants. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000400606 |
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| Hafez-Ghoran,Salar; Ebrahimi,Pouneh; Mighani,Hossein; Saeidnia,Soudabeh. |
| abstract Medicinal plants have many traditional claims including the treatment of ailments of infectious origin. In the evaluation of traditional claims, scientific research is extremely important. In this study, five homoisoflavonoids named 3-(4'-hydroxybenzylidene)-5,7-dihydroxy-6-methoxychroman-4-one(Autumnalin),3-(4'-hydroxybenzyl)-5,7-dihydroxy-6-methoxychroman-4-one (3,9-dihydro-autumnalin), 3-(3',4'-dihydroxybenzyl)-5,8-dihydroxy-7-methoxychroman-4-one,3-(3',4'-dihydroxybenzylidene)-5,8-dihydroxy-7-methoxychroman-4-one and 3-(3',4'-dihydroxybenzylidene)-5,7-dihydroxy-6-methoxychroman-4-one, were isolated from the bulbs of the plant Scilla persica HAUSSKN. Their structures were established on the basis of extensive spectroscopic analyses such as NMR,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: ScillapersicaHAUSSKN/phytochemistry; Homoisoflavonoids/isolation; Medicinal plants. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000400949 |
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| Melo,Marcelia Garcez Dória de; Araújo,Adriano Antunes de Souza; Serafini,Mairim Russo; Carvalho,Larissa Feitosa; Bezerra,Marília Santos; Ramos,Cledison Santos; Bonjardim,Leonardo Rigoldi; Albuquerque-Júnior,Ricardo Luiz Cavalcanti; Lima,Julianeli Tolentino; Siqueira,Rosana Souza; Fortes,Vanessa Silveira; Fonseca,Maria José Vieira; Quintans-Júnior,Lucindo José. |
| Atranorin (ATR) is the main compound from the lichen Cladina kalbii Ahti, which grows in the arid regions of northeastern Brazil. This study was conducted to evaluate the anti-inflammatory and toxicological properties of ATR. To evaluate anti-inflammatory properties, paw edema was induced by injecting 0.1 mL of carrageenan into the subplantar region of the right hind paw of rats, and leukocyte migration was induced by injection of 500 µL of carrageenan into the peritoneal cavity of mice. In addition, we determined ATR cytotoxicity in L929 cells by MTT assay and acute (5 g/kg-single dose) and subchronic (50 mg/kg-30 days) toxicity tests in Wistar rats. The results showed that ATR (100 mg/kg and 200 mg/kg) exhibited significant anti-inflammatory activity... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cladina kalbii/pharmacognosy; Atranorin/anti-inflamatory activity; Atranorin/toxicity; Medicinal plants. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000400024 |
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