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| Registros recuperados: 183 | |
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| Hashmi,Waleed Javed; Ismail,Hammad; Jafri,Laila; Mirza,Bushra. |
| In this study, we investigated the protective effects of Hedera nepalensis crude extract, its fractions and lupeol in alloxan-induced diabetic rats. Lupeol and n-hexane (HNN) fraction significantly reduced the blood glucose level by increasing insulin level in time dependent manner, and also significantly increased amylase and lipase activity in diabetic rats. Elevated levels of alanine transaminases (ALT), aspartate transaminases (AST), thiobarbituric acid reactive substances (TBARS), nitrite, hydrogen peroxide (H2O2), total bilirubin and total protein in blood serum were efficiently restored to normal levels. Suppressed enzymatic activity of catalase (CAT), superoxide dismutase (SOD), reduced glutathione (GSH) and peroxidase (POD) were also restored to... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antioxidant; Amylase; Diabetes mellitus; Insulin; Hedera nepalensis; Lupeol. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100597 |
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| Santos,Graciela Cristina dos; Antunes,Lusânia Maria Greggi; Santos,Antonio Cardozo dos; Bianchi,Maria de Lourdes Pires. |
| According to clinical and pre-clinical studies, oxidative stress and its consequences may be the cause or, at least, a contributing factor, to a large number of neurodegenerative diseases. These diseases include common and debilitating disorders, characterized by progressive and irreversible loss of neurons in specific regions of the brain. The most common neurodegenerative diseases are Parkinson's disease, Huntington's disease, Alzheimer's disease and amyotrophic lateral sclerosis. Coenzyme Q10 (CoQ10) has been extensively studied since its discovery in 1957. It is a component of the electron transportation chain and participates in aerobic cellular respiration, generating energy in the form of adenosine triphosphate (ATP). The property of CoQ10 to act as... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Coenzyme Q10; Antioxidant; Oxidative stress; Neurodegenerative diseases. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000400002 |
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| Shirinzadeh,Hanif; Ghalia,Mohammed; Tascioglu,Alev; Adjali,Ferial Intissar; Gunesacar,Gulsen; Gurer-Orhan,Hande; Suzen,Sibel. |
| Melatonin (MLT) is a strong free radical scavenger that protects the body from the deleterious effects of excess oxidants. Synthesis of MLT analogue compounds with antioxidant potency has recently attracted the interest of researchers. In general, the strategy consists of modifying the groups in the different sites of the indole ring or replacing the indole ring with an analogue. As part of our ongoing research, the antioxidant capacity and cytotoxicity of newly synthesized MLT analogue naphthalene derivatives were evaluated. The radical scavenging activity was tested by a 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. Most of the synthesized compounds showed significant antioxidant activity in comparison to MLT. The structure-activity relationship was... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antioxidant; Cytotoxic; Melatonin; MTT; DPPH. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100550 |
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| Abdallah,Walid Elsayed; Elsayed,Wael Mohamady; Hassan,Rasmia Ali; Nazif,Naglaa Mohammed; Ali,Mohammed Ibrahim; Abdelshafeek,Khaled Abdelhady. |
| Investigation of the lipid constituents of the aerial parts of Phyllanthus atropurpureus resulted in isolation and identification of the fatty acid mixture which consists of eight acids with linolenic acid as major and the unsaponifiable fraction that contain a series of hydrocabons, sterols, in addition to one triterpene (α-amyrin). The acetone insoluble fraction was found to contain two fatty alcohols and three n-hydrocabons in which the n-eicosane is the most abundant (44.16%). The flavonoidal constituents were isolated from ethyl acetate and butanol fractions which were identified as: luteolin-7-O-glucoside, kaempferol 3-O-(p-coumaroylglucoside), kaempferitrin, luteolin and kaempferol. Evaluation of different extracts as acetylcholinesterase inhibitors... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Phyllanthus atropurpureus; Euphorbiaceae; Flavonoids; Acetylcholineesterase inhibitors; Antioxidant. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100575 |
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| Barata-Soares,Anderson D.; Gomez,Maria Luiza P. A.; Mesquita,Carlos Henrique de; Lajolo,Franco M.. |
| Since the first isolation of ascorbic acid (AsA) in 1928, few papers have been published regarding the biosynthesis of AsA in plants, especially in fruits. It took as long as 1998, before Wheeler, Jones and Smirnoff, based on a study with Arabidopsis leaves, proposed what can be considered the main pathway of biosynthesis of AsA, in which L-galactose (L-GAL) is a key precursor. This paper reports the effectiveness of some precursors (cold or radiolabeled) in the biosynthesis of AsA in different plants: green sweet pepper, white-pulp guava, red-pulp guava, papaya and strawberry at two ripening stages (mature green and ripe for papaya and mature green and half red for strawberry) and broccoli. The 'Smirnoff-Wheeler' pathway was functioning and active in all... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ascorbate; Ascorbate biosynthesis pathway; Antioxidant; Precursor infiltration. |
| Ano: 2004 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-04202004000300004 |
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| Burris,Kellie P; Harte,Federico M; Michael Davidson,P; Neal Stewart Jr,C; Zivanovic,Svetlana. |
| Yerba Mate is a popular tea beverage produced and consumed in the South American countries of Argentina, Brazil, Chile, Paraguay, and Uruguay, and is processed from the leaves and stems of Ilex paraguariensis A. St.-Hil., a perennial shrub from the Aquifoliaceae family. Production occurs in six stages: harvesting older leaves and small stems, roasting by direct fire, drying under hot air, milling to specified size, aging to acquire optimal sensory attributes, and final packaging. While grown and consumed for centuries in South America, its popularity is increasing in the United States because of demand by consumers for healthier, more natural foods, its filling a niche for a different type of tea beverage, and for Yerba Mate's potential health benefits -... |
| Tipo: Journal article |
Palavras-chave: Antioxidant; Antimicrobials; Natural products; Yerba mate; Tea. |
| Ano: 2012 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-58392012000200016 |
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| Meriño-Gergichevich,Cristian; Pacheco,Eduardo; Reyes-Díaz,Marjorie. |
| C. Meriño-Gergichevich, E. Pacheco, and M. Reyes-Díaz. 2016. The effect of foliar boron spraying on the fruit features of Brigitta and Legacy highbush blueberry (Vaccinium corymbosum) cultivars. Cien. Inv. Agr. 43(3):452-463. Boron (B) is associated with reproductive and antioxidant metabolism in plants, and in southern Chile, the deficiency of this micronutrient is ameliorated through foliar applications that are a part of agricultural management, thus ensuring the productivity of crops including highbush blueberry (Vaccinium corymbosum L.). However, the appropriate B dosage for this species is unknown, so the aim of this study was to evaluate foliar B application on fruit quality in highbush blueberry in southern Chile. During the 2014-2015 season,... |
| Tipo: Journal article |
Palavras-chave: Antioxidant; DPPH; Fruit quality; Micronutrient; ORAC. |
| Ano: 2016 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-16202016000300011 |
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| Öztürk,Burhan; Altuntas,Ebubekir; Yildiz,Kenan; Ozkan,Yakup; Saracoglu,Onur. |
| Recently, plant growth regulators have been used for various purposes in apples. Methyl jasmonate (MeJA) has significant effects on the physiology, postharvest biology, processing, and chemical composition of apples. In the present study, the effects of MeJAMeJa treatments on the physicochemical quality and bioactive compounds (total antioxidant activity, total phenolics, and total anthocyanins) of 'Fuji' apples were investigated. The following doses of MeJa were used: 0 (control); 1; 120; 2,240; and 4,480 mg L-1. The highest geometric mean diameter, fruit mass, flesh firmness and skin thickness were obtained from the 2,240 mg L-1 MeJA treatment. Fruits harvested from control trees exhibited the highest total soluble solids content (TSSC) and pH, whereas... |
| Tipo: Journal article |
Palavras-chave: Apple; Antioxidant; Color; Firmness; Methyl jasmonate; Phenolics. |
| Ano: 2013 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-16202013000100018 |
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| Riquelme,Javiera; Olaeta,José Antonio; Gálvez,Lena; Undurraga,Pedro; Fuentealba,Claudia; Osses,Andrea; Orellana,Jaime; Gallardo,José; Pedreschi,Romina. |
| Sarcocornia neei is a halophyte that grows on the coast of the Valparaiso Region of Chile. Studies related to its nutritional and functional value under wild and cultivated conditions are not available. Thus, in this study, a nutritional (complete proximal, mineral and dietary fiber analysis) and functional characterization (total phenolics, β-carotene, hydrophilic and lipophilic antioxidant activity (HAA and LAA) and ascorbic acid) were performed for wild and cultivated plants. Wild plants displayed higher amounts of compounds involved in stress defense mechanisms such as total phenolics, proteins, dietary fiber and ash. The mineral analysis revealed that Na+ and Cl- are the main ions accumulated in wild and cultivated Sarcocornia neei that are... |
| Tipo: Journal article |
Palavras-chave: Antioxidant; Dietary fiber; Proximal analysis; Seawater; Sustainability. |
| Ano: 2016 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-16202016000200011 |
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| Araujo,Luciana Oliveira de; Nogueira,Carlos Eduardo Wayne; Pazinato,Fernanda Maria; Frey Junior,Friedrich; Paixão,Silvano Costa; Souza,Letícia da Silva; Curcio,Bruna da Rosa. |
| ABSTRACT: The aim of this study was to evaluate the effects of Allopurinol in foals born from mares with placentitis. Twenty foals were assigned into two groups: Healthy foals (n=10), born from healthy mares and Placentitis foals (n=10), born from mares with placentitis. Five foals from each group were randomly assigned to a treatment or control group. Treatment groups received Allopurinol (40mg kg-1 orally six hours after birth). Blood samples were collected for estimation of hematological variables and serum concentration of calcium, chloride, creatinine, phosphorus, glucose, lactate and magnesium. Placentitis foals presented leukopenia and neutropenia when compared with Healthy foals, at birth. The white blood cell (WBC) count was lower in the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Neonatology; Antioxidant; Therapeutic; Biochemical; Hematology.. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782016000601119 |
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| Kumbasar,Serkan; Cetin,Nihal; Yapca,Omer Erkan; Sener,Ebru; Isaoglu,Unal; Yilmaz,ehmet; Salman,Suleyman; Aksoy,Ayse Nur; Gul,Mehmet Ali; Suleyman,Halis. |
| In this study, xanthine oxidase (XO), malondialdehyde (MDA), myeloperoxidase (MPO) and glutathione (GSH) levels in the ovarian tissues of rats during the development of ischemia and postischemia-induced reperfusion were investigated, and the effect of ATP on ischemia-reperfusion (I/R) damage was biochemically and histopathologically examined. The results of the biochemical analyses demonstrated that ATP significantly reduced the level of XO and MDA and increased the amount of GSH in both ischemia and I/R-applied ovarian tissue at the doses administered. Furthermore, ATP significantly suppressed the increase in MPO activity that occurred following the application of post ischemia reperfusion in the ovarian tissue. The biochemical results obtained in the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Xanthine oxidase metabolism; Ischemia/reperfusion injury; Antioxidant; Rat. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782014000701257 |
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| Batista,Vanessa Sabrina Fagundes; Nunes,Graciele Lorenzoni; Viegas,Gabriela Ilha; Lucas,Bruna Nichelle; Bochi,Vivian Caetano; Emanuelli,Tatiana; Barin,Juliano Smanioto; Menezes,Cristiano Ragagnin de; Rosa,Claudia Severo da. |
| ABSTRACT: This study aimed to extract isoflavones from soybean molasses with different solvents, furthermore, the selected extract, which showed overall desirable characteristics was selected to evaluate the potentials of different encapsulating agents. The encapsulating agents employed for the study included 18% Maltodextrin DE20 (T1), 18% Hi-maize (T2), and a mixture of equal proportions of 9% Maltodextrin DE20 and 9% of Hi-maize (T3). Solvents such as 80% ethanol and methanol, and grain alcohol in varying different concentrations of 50 and 80% were used for the studies. The best solvent for the extraction of phenolics and total isoflavones was 50% cereal alcohol, this extract also presented higher antioxidant activity. Evaluation of the encapsulating... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Spray-drying; Antioxidant; Phenolics; Isoflavones. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782020000300751 |
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| Lima,Denise Simim; Duarte,Nathália Barroso Almeida; Barreto,Débora Luiza Costa; Oliveira,Geane Pereira de; Takahashi,Jacqueline Aparecida; Fabrini,Sabrina Pinheiro; Sande,Denise. |
| ABSTRACT: The waste in the fruit production chain, including the juice and pulp industries, produces large quantities of leftover husks, seeds and bagasse. This volume of waste generates huge environmental and economic impact. The objective of this research was to determine the potential of using residues from passion fruit (Passiflora edulis) and apple (Malus domestica) varieties in the production of functional flours. Passion fruit flour showed greater reduction of DPPH (EC50%: 50.4μg/mL) radicals, showing antioxidant potential, as well as a more efficient inhibition of Staphylococcus aureus (71.3±1.2μg/mL), with a modest; however efficient, inhibition of acetylcholinesterase (10%). All Apple flours were good antioxidants and the fuji apple flour stood... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Acetylcholinesterase; Agroindustrial residues; Antioxidant; Natural preservative. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782018000900754 |
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| Scola,Gustavo; Kappel,Virginia Demarchi; Moreira,José Claudio Fonseca; Dal-Pizzol,Felipe; Salvador,Mirian. |
| There are many studies about the biological activities of Vitis vinifera grape seeds, which are rich in phenolic compounds, known by their several health beneficial effects. However, until now there is no data about biological activities of the seeds of V. labrusca, specie found in South and North America. Every year, the global wine production (around 260 million hL) generates about 19.5 million ton of wastes, which are usually discarded in the environment. The aim of this research was to evaluate the antioxidant and anti-inflammatory activities of aqueous extracts of seeds from wine wastes of Vitis labrusca (cv. 'Bordo' and 'Isabella'). Both extracts showed significant antioxidant and anti-inflammatory activities, which are positively correlated with... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: V. labrusca; Winery wastes; Antioxidant; Anti-inflammatory. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782011000700020 |
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| Registros recuperados: 183 | |
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