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Gallardo-Casas,CA; Guevara-Balcázar,G; Morales-Ramos,E; Tadeo-Jiménez,Y; Gutiérrez-Flores,O; Jiménez-Sánchez,N; Valadez-Omaña,MT; Valenzuela-Vargas,MT; Castillo-Hernández,MC. |
In Mexico, medicinal plants are widely used. The use of Randia aculeata by healers against snakebites has never been scientifically tested in relation to possible effects on blood parameters and muscle tissue damage. Interviews were carried out in Jamapa, Veracuz, Mexico, with local residents to collect information about the traditional use of Randia aculeata. In this locality, seven pieces of fruit from the plant are mixed in a liter of alcohol, and then administered orally against snakebites. By using histological techniques and a murine model, we explored its cytoprotective properties against the effects of Crotalus simus and Bothrops asper venoms. Possible protections provided by the plant against tissue damage to skeletal and cardiac muscles and... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rubiaceae; Antivenoms; Bothrops; Crotalus; Cytoprotection. |
Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992012000300006 |
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