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| Registros recuperados: 239 | |
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| VORONOV,E.; APTE,R. N.; SOFER,S.. |
| Envenomation by insects, snakes, scorpions, and spiders involves the activation of the inflammatory system with the release and activation of pro-inflammatory cytokines, chemotactic mediators, cellular infiltration, and other vasoactive mediators. Activation of the inflammatory system and its cascade of events play a major role in the pathogenesis of envenomation, its clinical picture, and outcome. Additional clinical and laboratory studies are required to characterize the exact mechanisms by which the inflammatory system affects the pathophysiology, clinical course, and complications following envenomations. A better understanding of the involvement of the inflammatory cascade in different envenoming syndromes may have future therapeutic benefits. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Systemic inflammatory response; Cytokines; Pro-inflammatory cytokines; Chemotactic mediators; Vasoactive mediators. |
| Ano: 1999 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301999000100002 |
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| MASVINGWE,C.; MAVENYENGWA,M.. |
| Major clinical signs were depression, vomiting, abdominal pain, weakness, recumbency, paddling convulsions terminating in death from 6 to 96 hours after ingestion. Gross pathological findings included ascites with fibrin strands, enlarged, congested and friable livers with accentuation of lobulation on the capsule. Microscopically, acute hepatic congestion and hemorrhage, centrilobular hepatocyte necrosis, with occasional binucleation together with discoid lysis of skeletal and cardiac muscle fibers were remarkable changes. Binucleation of hepatocytes and degenerative changes in active muscles have not been reported before in relation to cocklebur plant toxicosis. These findings suggest that X. strumarium is a potential cause of sudden death in pigs... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Xanthium strumarium toxicosis; Hepatocyte necrosis; Striated muscle fiber and renal tubular degeneration; Zimbabwe. |
| Ano: 1998 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301998000200003 |
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| MURUGESAN,S.; RADHA KRISHNA MURTHY,K.; NORONHA,O. P. D.; SAMUEL,A. M.. |
| Labelling of scorpion (Mesobuthus tamulus concanesis Pocock) venom was successfully achieved with Tc 99m using direct tin reduction procedure. Biodistribution studies were carried out in Wistar rats at different time intervals after i.v. administration of the labelled venom. Scintiimages were obtained after scorpion envenoming using a large field of view gamma camera to ascertain the pharmacological action of venom in the body. Within 5 min of administration, labelled venom was found in the blood (27.7%), muscle (30.11%), bone (13.3%), kidneys (11.5%), liver (10.4%), and other organs. The level of venom in the kidneys was higher than in the liver. The labelled venom was excreted through renal and hepatobiliary pathways. An immunoreactivity study was... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Mesobuthus tamulus concanesis; Tc 99m; Scorpion venom. |
| Ano: 1999 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301999000100003 |
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| LIPPS,B. V.. |
| The pharmacological substances adenosine deaminase (ADA), histamine, and IgE are endogenously present in animals. They are implicated in allergy and asthma and detectable in blood serum. This research reports the presence of ADA, histamine, and IgE at varying levels in almost all major organs of mice. This research further reports that intramuscular injection of sub-lethal dose of Naja kaouthia venom disrupted homeostasis and lowered the levels of ADA, histamine, and IgE in the organs of mice. Adult Balb/C male mice were injected with a half lethal dose of the venom. The mice were sacrificed at 2, 8, and 24 hours post-injection and different organs were collected. Organs were homogenized, centrifuged, and the supernatants were assayed for ADA, histamine,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cobra venom; Balb/C mice organs; Adenosine deaminase; Histamine; IgE; Naja kaouthia. |
| Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79302002000100006 |
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| Registros recuperados: 239 | |
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