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| Registros recuperados: 25 | |
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| GUIMARÃES,ZULMIRA A.S.; DAMATTA,RENATO A.; GUIMARÃES,RENAN S.; FILGUEIRA,MARCELLO. |
| ABSTRACT With the aim of introducing permanent prostheses with main properties equivalent to cortical human bone, Ti-diamond composites were processed through powder metallurgy. Grade 1 titanium and mixtures of Ti powder with 2%, 5% and 10 wt% diamond were compacted at 100MPa, and then sintered at 1250°C/2hr/10-6mbar. Sintered samples were studied in the point of view of their microstructures, structures, yield strength and elastic modulus. The results showed that the best addition of diamonds was 2 wt%, which led to a uniform porosity, yield strength of 370MPa and elastic modulus of 13.9 GPa. Samples of Ti and Ti-2% diamond were subjected to in vitro cytotoxicity test, using cultures of VERO cells, and it resulted in a biocompatible and nontoxic composite... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Biomaterials; Titanium; Diamond; Sintering; Characterization; Biocompatibility.. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000603111 |
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| LACERDA-SANTOS,ROGÉRIO; LIMA,ANTONIA BÁRBARA L.; PENHA,ELIZANDRA S. DA; SANTOS,ANTONIELSON DOS; CARVALHO,FABÍOLA G.; PITHON,MATHEUS M.; DANTAS,ANTÔNIO FLÁVIO M.. |
| Abstract the focus ofthis study was to testthe hypothesisthatthere would be no difference betweenthe biocompatibility of silicon dioxide nanofilms used as antimicrobial agents. Sixty male Wistar rats were divided into 4 groups (n=15): Group C (Control,Polyethylene), Group AR (Acrylic Resin), Group NP (Acrylic Resin coated with NP-Liquid), Group BG (Acrylic Resin coated with Bacterlon).the animals were sacrificed with 7,15 and 30 days and tissues analyzed as regardsthe events of inflammatory infiltrate, edema, necrosis, granulation tissue, mutinucleated giant cells, fibroblasts and collagen. Kruskal-Wallis and Dunn tests was used (P<0.05). Intense inflammatory infiltrate was shown mainly in Groups BG and AR, with significant difference from Control Group... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Biomaterials; Biocompatibility; Dentistry; Inflammation. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652020000100910 |
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| Vulcani,V.A.S.; Franzo,V.S.; Rabelo,R.E.; Rabbers,A.S.; Assis,B.M.; D'Ávila,M.A.; Antoni,S.M.B.. |
| Electrospinning is a technique that allows the preparation of nanofibers from various materials. Chitosan is a natural and abundant easily obtained polymer, which, in addition to those features, proved to be biocompatible. This work used nanostructured chitosan and polyoxyethylene membranes as subcutaneous implants in Wistar rats to evaluate the biocompatibility of the material. Samples of the material and tissues adjacent to the implant were collected 7, 15, 30, 45 and 60 days post-implantation. Macroscopic integration of the material to the tissues was observed in the samples and slides for histopathological examination that were prepared. It was noticed that the material does not stimulate the formation of adherences to the surrounding tissues and that... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Nanotechnology; Biomaterials; Electrospinning. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352015000401039 |
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| Reis,Emily Correna Carlo; Borges,Andréa Pacheco Batista; Fonseca,Cláudio César; Martinez,Mastoby Miguel Martinez; Eleotério,Renato Barros; Morato,Gláucia Oliveira; Oliveira,Paulo Miranda. |
| In this work, biocompatibility, osteointegration, osteoconductivity, and biodegradation of a hydroxyapatite polyhydroxybutyrate new composite were evaluated. The composite was implanted in rabbits' bone defects and clinical, radiographic, histological, and histomorphometric data of these animals were compared with those of unfilled defects on the days 8th, 45th, and 90th after surgery. No significant differences existed between the groups for the evaluated clinical parameters. Radiographs showed bone-composite direct contact. Bone formed within the defect, interface and inside the composite. Significant differences were found between the bone and connective tissues percentage within the defect at all dates and at the interface on the 45th day, bone tissue... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Biomaterials; Bone; Biocompatibility; Biodegradation; Hydroxyapatite-polyhydroxybutyrate composite. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132010000400010 |
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| Bellini,Márcia Zilioli; Oliva-Neto,Pedro de; Moraes,Ângela Maria. |
| In this study, the effects of the origin of xanthan used, in combination with chitosan, to prepare films for the treatment of skin lesions were evaluated. The characteristics of the films obtained with xanthan commercially available for the food industry sector and xanthan originated from a fermentation process conducted in a pilot plant were compared. Results showed that the source did not strongly interfere in many of the properties of the films, such as the mechanical properties, cytotoxicity to L929 cells, absorption of simulated body fluid and culture medium, stability in water and saline solution. Hence, even though the properties of biopolymers of different sources might vary, the films prepared with two distinct types of xanthan gum could be... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Biomaterials; Biopolymers; Films; Membranes; Properties and characterization; Biomedical applications. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000200289 |
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| Wodewotzky,T.I.; Lima-Neto,J.F.; Pereira-Júnior,O.C.M.; Sudano,M.J.; Lima,S.A.F.; Bersano,P.R.O.; Yoshioka,S.A.; Landim-Alvarenga,F.C.. |
| Support structures for dermal regeneration are composed of biodegradable and bioresorbable polymers, animal skin or tendons, or are bacteria products. The use of such materials is controversial due to their low efficiency. An important area within tissue engineering is the application of multipotent mesenchymal stromal cells (MSCs) to reparative surgery. The combined use of biodegradable membranes with stem cell therapy may lead to promising results for patients undergoing unsuccessful conventional treatments. Thus, the aim of this study was to test the efficacy of using membranes composed of anionic collagen with or without the addition of hyaluronic acid (HA) as a substrate for adhesion and in vitro differentiation of bone marrow-derived canine MSCs. The... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Collagen scaffolds; Biomaterials; Hyaluronic acid; Mesenchymal stromal cells; Tissue engineering; Cell culture. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012001200008 |
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| Rosa,A.R.; Steffens,D.; Santi,B.; Quintiliano,K.; Steffen,N.; Pilger,D.A.; Pranke,P.. |
| The association of bioactive molecules, such as vascular endothelial growth factor (VEGF), with nanofibers facilitates their controlled release, which could contribute to cellular migration and differentiation in tissue regeneration. In this research, the influence of their incorporation on a polylactic-co-glycolic acid (PLGA) scaffold produced by electrospinning on cell adhesion and viability and cytotoxicity was carried out in three groups: 1) PLGA/BSA/VEGF; 2) PLGA/BSA, and 3) PLGA. Morphology, fiber diameter, contact angle, loading efficiency and controlled release of VEGF of the biomaterials, among others, were measured. The nanofibers showed smooth surfaces without beads and with interconnected pores. PLGA/BSA/VEGF showed the smallest water contact... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Emulsion electrospinning; VEGF; Stem cells; PLGA; Biomaterials. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000900601 |
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| Santos Jr.,A.R.; Ferreira,B.M.P.; Duek,E.A.R.; Dolder,H.; Wada,M.L.F.. |
| Vero cells, a cell line established from the kidney of the African green monkey (Cercopithecus aethiops), were cultured in F-10 Ham medium supplemented with 10% fetal calf serum at 37°C on membranes of poly(L-lactic acid) (PLLA), poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV) and their blends in different proportions (100/0, 60/40, 50/50, 40/60, and 0/100). The present study evaluated morphology of cells grown on different polymeric substrates after 24 h of culture by scanning electron microscopy. Cell adhesion was also analyzed after 2 h of inoculation. For cell growth evaluation, the cells were maintained in culture for 48, 120, 240, and 360 h. For cytochemical study, the cells were cultured for 120 or 240 h, fixed, processed for histological analysis,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Poly(L-lactic acid); Poly(hydroxybutyrate- co-hydroxyvalerate); Blends; Biomaterials; Cell culture; Vero cells. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005001100009 |
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| Machado,L.G.; Savi,M.A.. |
| Shape memory alloys (SMA) are materials that have the ability to return to a former shape when subjected to an appropriate thermomechanical procedure. Pseudoelastic and shape memory effects are some of the behaviors presented by these alloys. The unique properties concerning these alloys have encouraged many investigators to look for applications of SMA in different fields of human knowledge. The purpose of this review article is to present a brief discussion of the thermomechanical behavior of SMA and to describe their most promising applications in the biomedical area. These include cardiovascular and orthopedic uses, and surgical instruments. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Shape memory alloys; Biomaterials. |
| Ano: 2003 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000600001 |
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| Nassif, L. Abi; Rioual, S.; Trepos, Rozenn; Fauchon, M.; Farah, W.; Hellio, C.; Abboud, M.; Lescop, B.. |
| Microorganisms have the ability to settle on nearly all man-made surfaces in contact with seawater and subsequently to form biofilm. Biofilms control and removal is necessary in the sectors of maritime transport, energy... In this work, we present the development of new pure calcium, zinc or copper alginate, but also mixed Ca/Cu and Ca/Zn alginate hydrogels. These materials have been evaluated for their potential inhibition of adhesion of two key biofilm-forming microalgae Halamphora coffeaeformis and Cylindrotheca closterium). All the tested materials have presented high adhesion inhibition about 80%). Copper-base materials present a high toxicity against H. coffeaeformis. Pure zinc alginate is also toxic for this strain. However, the addition of calcium... |
| Tipo: Text |
Palavras-chave: Biofilm; Adhesion; Alginate; Zinc; Biomaterials; Microalgae. |
| Ano: 2019 |
URL: https://archimer.ifremer.fr/doc/00605/71671/70168.pdf |
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| Issa,Joao Paulo Mardegan; Petenusci,Sergio Olavo; Siéssere,Selma; Regalo,Simone Cecilio Hallak; Lopes,Ruberval Armando; Di Matteo,Miguel Ángel Sala; Iyomasa,Mamie Mizusaki; Defino,Helton Luiz Aparecido. |
| The aim of this study was to evaluate the calcium dosage of the newly formed bone, in critical bone defects created on the calvarial tissue and filled by different substances, in male Wistar rats. A cylindrical critical bone defect (6x2mm) was created in the posterior portion, left side, on the calvarial bone in nine animals and filled with: animals' coagulum, monoolein gel, poloxamer gel, monoolein gel + 1µg rhBMP-2, monoolein gel + 3µg rhBMP-2, monoolein gel + 7µg rhBMP-2, poloxamer gel + 1µg rhBMP-2, poloxamer gel + 3µg rhBMP-2, poloxamer gel + 7µg rhBMP-2. The results of this study showed a positive correlation between the calcium dosage analysis and the newly formed bone |
| Tipo: Journal article |
Palavras-chave: Bone repair; Biomaterials; RhBMP-2; Carriers; Calcium. |
| Ano: 2007 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000300006 |
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| Beltrán,Victor; Matthijs,Andries; Borie,Eduardo; Fuentes,Ramón; Valdivia-Gandur,Iván; Engelke,Wilfried. |
| The centripetal resorption of maxilla is a continuous process after tooth loss. For treatment of deficient bone sites, autologous bone grafts may be used, as an alternative, biomaterials can be applied which do not require intra- or extraoral donor sites. The present report we describe the use of anorganic bovine bone (ABB) based on three case reports under different modes: Membrane, rigid barrier and connective tissue graft. Clinical results show that under all conditions, sufficient hard tissue was formed to allow implant born rehabilitation in the former insufficient bone sites. Histologic evaluation revealed trabecular bone in an almost mature matrix with resting particles of ABB. Depending on the original site situation, two step rigid occlusive... |
| Tipo: Journal article |
Palavras-chave: Bone regeneration; Maxilla; Dental implant; Bone defect; Biomaterials. |
| Ano: 2013 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000100011 |
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| Beltrán,Víctor; Engelke,Wilfried; Fuentes,Ramón; Decco,Oscar; Prieto,Ruth; Wilckens,Mario; Borie,Eduardo. |
| The centripetal resorption of maxilla is a continuous process after tooth loss. For treatment of deficient bone sites, autologous bone grafts may be used, as an alternative, biomaterials can be applied which do not require intra or extraoral donor sites. The present report describes the use of occlusive barriers and cortical particulate allograft in transverse maxillary defects. This surgical approach was performed in five patients (4 females and 1 male, aged 20 to 37 years). Clinical results show that sufficient hard tissue was formed to allow implant born rehabilitation in the former insufficient bone sites. Histological evaluation revealed small amounts of newly formed bone with a predominance of collagen fibrous tissue and mature bone with very little... |
| Tipo: Journal article |
Palavras-chave: Bone regeneration; Maxilla; Dental implant; Bone defect; Biomaterials. |
| Ano: 2014 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000100057 |
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| Registros recuperados: 25 | |
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